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From the same Team
The Essential MAK Value Documentations document the effects of occupational toxicants on the bronchial passage and inner organs, impact mechanisms, toxicokinetics and metabolism. This includes concrete data on whether a substance is carcinogenic, germ-cell mutagenic, sensitizing, or toxic to the reproductive system and whether it is resorbed by the skin in toxicologically significant amounts.
Substantiations for the biological exposure values (BAT Values), exposure equivalents for carcinogenic substances (EKA) as well as the biological values (BLW) are to be found in the Essential BAT Value Documentations. They contain characteristic data on metabolism and toxicokinetics while also describing exposure and the critical toxicity of the substances.
Two further volumes, Essential Air Monitoring Methods and Essential Biomonitoring Methods, present important, validated methods of analysis for monitoring concentrations at the work place. The regulations and protocols for evaluating the air quality and for biomonitoring among humans are also suitable for monitoring the environment. They correspond to modern standards of quality assurance and describe all required steps from sampling to the interpretation of results.
A special selection to start with...
The most important documentations and methods from the entire MAK Collection published in 4 essential volumes.
Indispensable for toxicologists, occupational and industrial physicians -- in fact anyone concerned with health protection and the establishment of safety regulations, the Essentials taken from the MAK Collection for Occupational Health and Safety list the most important MAK and BAT values e.g. for passive smoking, ozone and formaldehyde as well as suitable monitoring methods. | | | 
Greim, Helmut (ed.)
Essential MAK Value Documentations
from The MAK-Collection for Occupational Health and Safety
1. Edition - February 2006
129.- €
VIII, 489 Pages, Hardcover
ISBN-10: 3-527-31394-X
ISBN-13: 978-3-527-31394-5
Detailed description
For 17 of the most important occupational toxicants, the documentations for the established MAK values are provided. These include an authoritative review of the available toxicological studies and data. For every substance, toxic effects, mechanisms and modes of action, toxicogenetics and metabolism, effects in man and animals are described. The carcinogenic, germ-cell mutagenic, sensitizing or skin-resorptive effects as well as their toxicity to the reproductive system are evaluated. Basic physico-chemical data are provided as well. The documentations are thus not only essential for the application of MAK values but provide a concise toxicological overview for each substance.
The documentations are authoritative, because they were compiled by the Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area. The Commission is internationally acknowledged for its neutrality and is working strictly according to transparent, scientific criteria. MAK Values set the standards for legal regulations in many countries of the world, e. g. they are the basis for at least 30 % of the threshold limits valid in the European Union and they are also frequently referred to in China.
From the contents
GENERAL ASPECTS
Significance, use and derivation of MAK-Values
Changes of the classification of carcinogenic chemicals
Metal-working fluids, hydraulic fluids and lubricants
Sensitizing Substances
SUBSTANCES
alpha-Amylase
Arsenic, inorganic compounds
Carbon disulfide
Cereal flour dust
Chloroform
1,4-Dioxane
Dust, general threshold limit value
Ethanol
Ethylene glycol monobutyl ether
Ethylene oxide
Formaldehyde
Germ cell mutagens
Hexachlorobenzene
Ozone
Passive Smoking
Styrene
Trichloro ethylene
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Drexler, Hans / Greim, Helmut (eds.)
Essential BAT Value Documentations
from The MAK-Collection for Occupational Health and Safety
1. Edition - February 2006
129.- €
VIII, 357 Pages, Hardcover
ISBN-10: 3-527-31477-6
ISBN-13: 978-3-527-31477-5
Detailed description
For more than 20 of the most important occupational toxicants, the documentations for the established BAT values (Biological Exposure Values) and EKA values (Exposure Equivalents for Carcinogenic Substances) are provided. These include an authoritative review of the available toxicological studies and data. For every substance, metabolism and pharmacokinetics, critical toxicity, exposure and effects, suitable indicators of internal exposure, the evaluation of the BAT value and the correct interpretation of data are described. Basic physico-chemical data are provided as well. The documentations are thus not only essential for the application of BAT and EKA values but provide a concise overview of biological monitoring for each substance.
The documentations are authoritative, because they were compiled by the Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area. The Commission is internationally acknowledged for its neutrality and is working strictly according to transparent, scientific criteria. BAT Values set the standards for legal regulations in many countries of the world, e. g. they are the basis for at least 30 % of the threshold limits valid in the European Union.
From the contents
GENERAL ASPECTS
Concept of BAT-values
Concept of BLW-values
Concept of EKA
SUBSTANCES
Acetone
Alkali chromates
Aniline
Arsenic and inorganic arsenic compounds
Arsenic trioxide
Benzene
Butanone (2-Butanone)
Cobalt
Cresol (ortho)
Cyclohexane
Diaminodiphenyl methane
Dimethyl sulfate
Ethylene glycol monobutyl ether
Ethylene oxide
Hydrogen fluoride
Lead and its inorganic compounds (inhalable fraction) except lead arsenate and lead chromate
Methanol
Nickel and nickel compounds
Propanol (2-Propanol)
Styrene
Tetrachloro ethylene
Vinyl chloride
Xylene (all isomers)
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Parlar, Harun / Greim, Helmut (eds.)
Essential Air Monitoring Methods
from The MAK-Collection for Occupational Health and Safety
1. Edition - February 2006
125.- €
VIII, 418 Pages, Hardcover
ISBN-10: 3-527-31476-8
ISBN-13: 978-3-527-31476-8
Detailed description
For 16 of the most important occupational toxicants, detailed, ready-to-use protocols for air monitoring methods are provided. All methods are reliable, reproducible, in accordance with quality assurance standards and cover all required steps from sampling to the interpretation of results. This includes data on precision, accuracy, and detection limit, calibration procedures as well as potential sources of systematic errors. Advantages and Disadvantages of each method are clearly outlined.
The documented methods are authoritative, because they were compiled by the Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area. The Commission is internationally acknowledged for its neutrality and is working strictly according to transparent, scientific criteria.
From the contents
GENERAL ASPECTS
Passive Sampling
Quality control
Sampling and determining aerosols and their chemical components
Solvent Mixtures
SUBSTANCES
Aldehydes
Bitumen (vapour and aerosol)
Cadmium
Diesel engine emission
Ethylene glycol derivatives
Ethylene oxide
Formaldehyde
Metal-working fluids
N-Nitrosamines
PAH
Silica, crystalline (Quartz)
Styrene
Sulfuric acid
Tetrachloro ethylene (tetrachloroethene)
Trichloro ethylene
Volatile inorganic acids
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Angerer, Jürgen / Greim, Helmut (eds.)
Essential Biomonitoring Methods
from The MAK-Collection for Occupational Health and Safety
1. Edition - February 2006
132.- €
VIII, 450 Pages, Hardcover
ISBN-10: 3-527-31478-4
ISBN-13: 978-3-527-31478-2
Detailed description
For more than 30 of the most important occupational toxicants, detailed, ready-to-use protocols for human biomonitoring methods are provided. All methods are reliable, reproducible, in accordance with 'Good Laboratory Practice' standards and cover all required steps from sampling to the interpretation of results. This includes data on precision, accuracy, and detection limit, calibration procedures as well as potential sources of systematic errors.
The documented methods are authoritative, because they were compiled by the Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area. The Commission is internationally acknowledged for its neutrality and is working strictly according to transparent, scientific criteria.
From the contents
GENERAL ASPECTS
Preliminary remarks
Gas chromatographic methods for the determination of organic substances in biological materials
SUBSTANCES
Acrylonitrile
Alcohols and Ketones
Antimony
Aromatic carboxylic acids
Arsenic in urine
Benzene
Benzene and alkylbenzenes
Beryllium in urine - standard addition procedure
Bitumen (vapour and aerosol)
Butoxy acetic acid
Cadmium
Carbon disulfide
Chloroform
Cobalt
Cotinine in urine
Cyanoethylvalin N-2-Cyanoethylvalin, N-2-hydroxyethylvalin, N-2-methylvalin (Acrylnitril, Ethylen, Ethylenoxid, methylating agents)
Dimethyl sulfate
Ethanol
Ethylbenzene
Ethylene glycol monobutyl ether (Ethylene glycol derivatives)
Ethylene oxide
Halogenated hydrocarbons in blood (Tetrachloro ethylene)
Hexane metabolites in urine
Lead
t,t-Muconic acid, S-Phenyl mercapturic acid
Organochlorine compounds in whole blood and plasma
PAH metabolites in urine
Styrene
Tetrachloro ethylene (tetrachloroethene)
Thioxothiazolidine (2-Thioxothiazolidine-4-carboxylic acid)
Trichloro acetic acid in urine
Trichloro ethylene
Xylene (all isomers)
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