Wiley-VCH - Biomedical Engineering

Coordination Chemistry in Protein Cages

Ueno, Takafumi / Watanabe, Yoshihito — 20 May 2013 08:18:16 +0200

Written by highly respected pioneers in the field, Coordination Chemistry in Protein Cages addresses the assembly of and reactions inside protein cages, a rapidly developing area of chemistry. Logically organized into four parts (Coordination Chemistry in Native Protein Cages, Coordination Chemistry to Design Artificial Protein Functions, Applications in Biology, and Applications in Nanotechnology), the text addresses a new chemical approach in the synthesis of bioinorganic molecules which has been applied in a wide variety fields, including catalysis, biomedicine, and electronics. [408 Pages, Hardcover]

Read More...

Medical Imaging

Wolbarst, Anthony B. / Capasso, Patrizio / Wyant, Andrew R. — 20 May 2013 08:17:19 +0200

This book is a concise, one-stop resource on medical imaging written for medical professionals, addressing a field of critical importance to them, in the language that they speak. Coauthored by a medical physicist and a clinical imaging physician, the book provides a solid working knowledge of the science and technology of image formation, including coverage of imaging modalities and how they operate, how to use the resulting diagnostic information, the proper applications of imaging, and many clinical case examples. [432 Pages, Hardcover]

Read More...

Stem Cells

Meyers, Robert A. (ed.) — 24 Apr 2013 08:17:12 +0200

A topical volume on stem cell biology of the reputable Encyclopedia of Cell and Molecular Biology and Molecular Medicine combining the updates of the best existing content with more than 80% new articles covering recent developments in stem cell biology. [XL, 1060 Pages, Hardcover]

Read More...

Atlas of Living Cell Cultures

Lindl, Toni / Steubing, Rosemarie — 24 Apr 2013 08:17:10 +0200

The first atlas in many years giving researchers a good visual reference of the status of their cell lines. Given the increasing importance of well defined cellular models in particular in biomedical research this is a sorely needed resource for everyone performing cell culture. [521 Pages, Hardcover]

Read More...

Multiscale Simulations and Mechanics of Biological Materials

Qian, Dong — 15 Apr 2013 08:18:13 +0200

This text offers a unique interdisciplinary approach to multiscale biomaterial modeling aimed at both accessible introductory and advanced levels. It presents a breadth of computational approaches for modeling biological materials across multiple length scales (molecular to whole-tissue scale), including solid and fluid based approaches. Contributors to this volume are some of the most active researchers in multiscale simulations in the world, making this an authoritative reference for academia and industry. [480 Pages, Hardcover]

Read More...

The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging

Merbach, Andre S. / Helm, Lothar / Tóth, Éva — 8 Apr 2013 08:18:32 +0200

Magnetic Resonance Imaging (MRI) is one of the most important tools in clinical diagnostics and biomedical research. This completely revised and extended second edition is presented in color and includes new chapters on targeted, responsive, PARACEST and nanoparticle MRI contrast agents. It covers the basic chemistries, MR physics and most important techniques used by chemists in the characterization of MRI agents from every angle, from synthesis to safety considerations. Essential reading for professionals involved in the development and application of contrast agents in MRI. [512 Pages, Hardcover]

Read More...

Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering

Tiwari / Tiwari, Atul — 20 Mar 2013 08:17:29 +0100

Nanoscopic therapeutic systems incorporate therapeutic agents, molecular targeting and diagnostic imaging capabilities and are emerging as the next generation of multifarious nanomedicine to improve the therapeutic outcome including chemo and translational therapy. This reference work is one of the first to cover Nanotheragnostics which is the new edge of nanomedicine combining both diagnostic and therapeutic elements at nano level. This large multidisciplinary reference work is has four main parts: Biocompatible Nanomaterials; Nanomedicine: Drug Gene and Cell Delivery; Multi-functional Nanocarrier: Diagnosis, Imaging and Treatment; Tissue Engineering/Regenerative Medicine. [576 Pages, Hardcover]

Read More...

Integrated Pharmaceutics

Al-Achi, Antoine / Gupta, Mali Ram / Stagner, William Craig — 18 Mar 2013 08:17:16 +0100

Focusing on the application of physical pharmacy, drug design, and drug regulations as they relate to produce effective dosage forms for drug delivery, Integrated Pharmaceutics provides a comprehensive picture of pharmaceutical product design, describing the science and art behind the concepts of dosage form development. Combining physical pharmacy, product design, and regulatory affairs issues in a single book, the authors address topics governing drug regulations of United States, European, and Japanese agencies and detail new regulatory guidelines, including quality by design, design space analysis, and blend sample uniformity. [1016 Pages, Hardcover]

Read More...

Control of Biological and Drug-Delivery Systems for Chemical, Biomedical, and Pharmaceutical Engineering

Simon, Laurent — 4 Feb 2013 08:17:28 +0100

This book combines knowledge of process dynamics and basic control theory to analyze a range of bioprocesses and drug-release devices. The book addresses issues and solves problems that dominate both fields (i.e., biological sciences and release devices.) Many of the textbooks written on this topic usually focus on specific topics (e.g., systems biology, control of fermentation processes), as a result, undergraduate chemical engineering students are not exposed to a range of diversified problems in biological sciences. This book builds on the new focus of providing problems in the biological area. In addition, unified theories and step-by-step problem solving procedures are provided. A unique feature of the book is the application of control theory to analyze controlled-release devices. An expected outcome of the proposed perspective is an enrichment of fundamental concepts and the development of an application-oriented environment. For example pharmaceutical companies, specializing in the production of therapeutics using biological processes, are the first beneficiaries. A qualified labor force, with competencies in process analysis, design and control will assure that the target quantity and quality of the end-products are met and in line with federal and state regulations. [384 Pages, Hardcover]

Read More...

Electronic Health Record

30 Jan 2013 08:17:39 +0100

Discover How Electronic Health Records Are Built to Drive the Next Generation of Healthcare Delivery The increased role of IT in the healthcare sector has led to the coining of a new phrase health informatics, which deals with the use of IT for better healthcare services. Health informatics applications often involve maintaining the health records of individuals, in digital form, which is referred to as an Electronic Health Record (EHR). Building and implementing an EHR infrastructure requires an understanding of healthcare standards, coding systems, and frameworks. This book provides an overview of different health informatics resources and artifacts that underlie the design and development of interoperable healthcare systems and applications. Electronic Health Record: Standards, Coding Systems, Frameworks, and Infrastructures compiles, for the first time, study and analysis results that EHR professionals previously had to gather from multiple sources. It benefits readers by giving them an understanding of what roles a particular healthcare standard, code, or framework plays in EHR design and overall IT-enabled healthcare services along with the issues involved. This book on Electronic Health Record: * Offers the most comprehensive coverage of available EHR Standards including ISO, European Union Standards, and national initiatives by Sweden, the Netherlands, Canada, Australia, and many others * Provides assessment of existing standards * Includes a glossary of frequently used terms in the area of EHR * Contains numerous diagrams and illustrations to facilitate comprehension * Discusses security and reliability of data [376 Pages, Hardcover]

Read More...

Imaging gaseous detectors and their applications

Nappi, Eugenio / Peskov, Vladimir — 17 Jan 2013 08:17:43 +0100

Describing advanced detectors and their visualization and investigation techniques, this book presents the major applications in nuclear and high-energy physics, astrophysics, medicine and radiation measurements. [XXXII, 324 Pages, Hardcover]

Read More...

Nano and Cell Mechanics

Espinosa, Horacio D. / Bao, Gang — 14 Jan 2013 08:19:50 +0100

Highlights current trends in nano and cell mechanics with contributions from leading experts Nano and Cell Mechanics presents current trends in nano and cell mechanics in chapters contributed by distinguished and prominent investigators in the area of mechanics. It provides a review of mechanics applied to the broader fields of materials, electronic devices, energy and medicine. Nano and Cell Mechanics: * Is a comprehensive and detailed reference for the applied mechanics community, consisting of contributions from leaders in the field. * Presents current trends in the emerging areas of nano and cell mechanics. * Covers 'hot' topics of protein mechanics and hydrophobic surfaces. * Addresses the state-of art modelling and experimental characterization. Nano and Cell Mechanics is the primary point of reference for researchers and practising engineers and a text for advanced students. [506 Pages, Hardcover]

Read More...

Computational Fluid-Structure Interaction

Bazilevs, Yuri / Takizawa, Kenji / Tezduyar, Tayfun E. — 14 Jan 2013 08:18:40 +0100

Computational fluid-structure interaction (CFSI) is a rapidly expanding area of research, owing to its numerous applications, from vascular blood flow to the dynamics of wind turbines. The first book to present the state of the art of CFSI research, this complete, self-contained reference takes the reader from the fundamentals of computational fluid and solid mechanics all the way to cutting-edge research. Written by leading experts in the field, the book uses the modern language of computational mechanics and a unique approach that combines advanced theory and applications. [404 Pages, Hardcover]

Read More...

Body Area Communications

Wang, Jianqing / Wang, Qiong — 7 Jan 2013 08:18:13 +0100

Providing an introduction to the fundamentals of body area communications, this book covers the key topics of channel modeling, modulation and demodulation, and performance evaluation A systematic introduction to body area networks (BAN), this book focuses on three major parts: channel modeling, modulation/demodulation communications performance, and electromagnetic compatibility considerations. The content is logically structured to lead readers from an introductory level through to in-depth and more advanced topics. * Provides a concise introduction to this emerging topic based on classroom-tested materials * Details the latest IEEE 802.15.6 standard activities * Moves from very basic physics, to useful mathematic models, and then to practical considerations * Covers not only EM physics and communications, but also biological applications * Topics approached include: link budget, bit error rate performance, RAKE and diversity reception; SAR analysis for human safety evaluation; and modeling of electromagnetic interference to implanted cardiac pacemakers * Provides Matlab and Fortran programs for download from the Companion Website [288 Pages, Hardcover]

Read More...

Medical Devices

Culjat, Martin / Singh, Rahul / Lee, Hua — 12 Dec 2012 08:17:26 +0100

Bioengineering has become one of the most exciting majors in engineering programs everywhere. Medical Devices is a textbook for an introductory seminar course on the biomedical devices field. The book covers devices and systems in diagnostic, surgical, and implant procedures, prepared by the much-respected faculty members at the UCLA School of Medicine. The chapters are written and organized in the form of independent modules, such that lectures can be configured with a high degree of flexibility from year to year. It is designed for students in freshman year seminars/introductory biomedical engineering courses. [456 Pages, Hardcover]

Read More...

Bioinspiration and Biomimicry in Chemistry

Swiegers, Gerhard (ed.) — 10 Dec 2012 08:19:45 +0100

This book reviews and summarizes the many and varied forms of bioinspiration and biomimicry that are found in chemistry, from the crude to the highly sophisticated, from the near-biological to the totally industrial and abiological. It critically evaluates our true understanding of biological processes and systems by considering our ability to replicate them in non-biological settings. Research chemists will find critical and holistic evaluation of chemical processes in nature. [508 Pages, Hardcover]

Read More...

Tactile Sensing and Display

Dargahi, Javad / Sokhanvar, Saeed / Najarian, Siamak / Arbatani, Siamak — 3 Dec 2012 08:19:14 +0100

This reference comprehensively covers the key technologies for the development of tactile perception in minimally invasive surgery (MIS), including teletaction, tactic display, and intelligent tactile sensing. The coverage describes the mechanisms, methods, and sensors that measure and display kinaesthetic and tactile data between a surgical tool and tissue. Written by authors at the cutting-edge of research into the area of tactile perception in minimally invasive surgery, this resource illuminates a key topic for academic researchers, graduate students, and professionals working in the area. [282 Pages, Hardcover]

Read More...

Biomedical Materials and Diagnostic Devices

Tiwari / Ramalingam, Murugan / Kobayashi, Hisashi / Turner, Anthony P. F. (eds.) — 1 Nov 2012 08:17:52 +0100

The functional materials with the most promising outlook have the ability to precisely adjust the biological phenomenon in a controlled mode. Engineering of advanced bio- materials has found striking applications in used for biomedical and diagnostic device applications, such as cell separation, stem-cell, drug delivery, hyperthermia, automated DNA extraction, gene targeting, resonance imaging, biosensors, tissue engineering and organ regeneration. [640 Pages, Hardcover]

Read More...

Forensic Biomechanics

Kieser, Jules / Taylor, Michael / Carr, Debra — 29 Oct 2012 08:19:42 +0100

Biomechanics is the application of mechanical principles to living organisms, and it is one of the most exciting and fastest growing research areas. In forensic science, it is biomechanics that explains trauma to the body at a crime scene or the fracture of fibers and textiles, and helps interpret blood spatter. Forensic Biomechanics is a comprehensive overview of the role of biomechanics in forensics. Well-illustrated with real-life case studies, and using a multidisciplinary approach, this unique book is an invaluable reference for practicing forensic scientists, lawyers, and researchers. [176 Pages, Hardcover]

Read More...

Hybrid Control and Motion Planning of Dynamical Legged Locomotion

Sadati, Nasser / Dumont, Guy A. / Hamed, Kaveh Akabri / Gruver, William A. — 29 Oct 2012 08:18:57 +0100

This book provides a comprehensive presentation of issues and challenges faced by researchers and practicing engineers in motion planning and hybrid control of dynamical legged locomotion. The major features range from offline and online motion planning algorithms to generate desired feasible periodic walking and running motions and tow-level control schemes, including within-stride feedback laws, continuous time update laws and event-based update laws, to asymptotically stabilize the generated desired periodic orbits. This book describes the current state of the art and future directions across all domains of dynamical legged locomotion so that readers can extend proposed motion planning algorithms and control methodologies to other types of planar and 3D legged robots. [272 Pages, Hardcover]

Read More...

Biomimetic Approaches for Biomaterials Development

Mano, Joao F. (ed.) — 25 Oct 2012 08:17:12 +0200

This fruitful collaboration between materials science, biology and biomedicine for the advancement of biomaterials collects the most promising solutions provided by nature for the field of biomedicine, showing how to achieve the desired functionality by using biomimetics. [XXXII, 574 Pages, Hardcover]

Read More...

Introductory Bioelectronics

Pethig, Ronald R. / Smith, Stewart — 15 Oct 2012 08:18:51 +0200

With its interdisciplinary approach to basic theory, practical examples, and clinical applications, this is the only book available on the topic that is suitable for students. Emphasizing the fundamentals of biochemical, biophysical, electrical, and physiological concepts relevant to bioelectronics, it delivers the necessary biological knowledge from an electrical engineer's perspective. It also contains new developments in bioelectronics and biosensors, such as microfluidic devices and nanotechnology. Each chapter contains a problem section that readers can use for self-assessment, and model answers and references are given at the end of the book. [462 Pages, Hardcover]

Read More...

Integrated Biomaterials for Biomedical Technology

Ramalingam, Murugan / Tiwari / Ramakrishna, Seeram / Kobayashi, Hisatoshi (eds.) — 20 Aug 2012 08:18:15 +0200

This cutting edge book provides all the important aspects dealing with the basic science involved in materials in biomedical technology, especially structure and properties, techniques and technological innovations in material processing and characterizations, as well as the applications. The volume consists of 12 chapters written by acknowledged experts of the biomaterials field and covers a wide range of topics and applications. [440 Pages, Hardcover]

Read More...

Glass Ceramic Technology

Holand, Wolfram / Beall, George H. — 27 Jul 2012 08:17:22 +0200

Glass-ceramic materials share many properties with both glass and more traditional crystalline ceramics. This new edition examines the various types of glass-ceramic materials, the methods of their development, and their countless applications. With expanded sections on biomaterials and highly bioactive products (i.e., Bioglass and related glass ceramics), as well as the newest mechanisms for the development of dental ceramics and theories on the development of nano-scaled glass-ceramics, here is a must-have guide for ceramic and materials engineers, managers, and designers in the ceramic and glass industry. [440 Pages, Hardcover]

Read More...

The Elements of Continuum Biomechanics

Epstein, Marcelo — 23 Jul 2012 08:18:21 +0200

An appealing and engaging introduction to Continuum Mechanics in Biosciences This book presents the elements of Continuum Mechanics to people interested in applications to biological systems. It is divided into two parts, the first of which introduces the basic concepts within a strictly one-dimensional spatial context. This policy has been adopted so as to allow the newcomer to Continuum Mechanics to appreciate how the theory can be applied to important issues in Biomechanics from the very beginning. These include mechanical and thermodynamical balance, materials with fading memory and chemically reacting mixtures. In the second part of the book, the fully fledged three-dimensional theory is presented and applied to hyperelasticity of soft tissue, and to theories of remodeling, aging and growth. The book closes with a chapter devoted to Finite Element analysis. These and other topics are illustrated with case studies motivated by biomedical applications, such as vibration of air in the air canal, hyperthermia treatment of tumours, striated muscle memory, biphasic model of cartilage and adaptive elasticity of bone. The book offers a challenging and appealing introduction to Continuum Mechanics for students and researchers of biomechanics, and other engineering and scientific disciplines. Key features: * Explains continuum mechanics using examples from biomechanics for a uniquely accessible introduction to the topic * Moves from foundation topics, such as kinematics and balance laws, to more advanced areas such as theories of growth and the finite element method.. * Transition from a one-dimensional approach to the general theory gives the book broad coverage, providing a clear introduction for beginners new to the topic, as well as an excellent foundation for those considering moving to more advanced application [392 Pages, Hardcover]

Read More...

Dendrimer-Based Drug Delivery Systems

Cheng, Yiyun (ed.) — 23 Jul 2012 08:17:15 +0200

This book focuses on the formulation and delivery of dendrimers. It offers both a comprehensive introduction and reference to practical applications. The coverage encompasses dendritic drug delivery systems ranging from dendrimers chemistry to cellular uptake of dendritic nanoparticles. With the specific application of dendrimers in drug and biologic delivery, the text highlights their versatility in solving development issues in a wide class of drugs. Discussing all the unique opportunities, issues, and challenges involved in exploiting dendrimers for improving drug delivery, this book helps pharmaceutical and related scientists understand and work with this drug carrier. [534 Pages, Hardcover]

Read More...

Synthetic Biology

Schmidt, Markus (ed.) — 19 Jul 2012 08:17:25 +0200

The first text to cover all aspects of the field including ethical issues. An indispensable companion for students and decision makers. [XXVI, 240 Pages, Hardcover]

Read More...

Bio-Glasses

Jones, Julian / Clare, Alexis — 9 Jul 2012 08:17:38 +0200

The first book dedicated to glasses and their variants that can be used as biomaterials to repair diseased and damaged tissues, this book covers all types of glasses: traditional glasses, bioactive glasses, sol-gel glasses, phosphate glasses, glass-ceramics, composites and hybrids. With discussion on how they are made, their properties, and the reasons for their use, the authors also cover their applications in dentistry, bone regeneration and tissue engineering, and cancer treatment. Its solid guidance describes the steps needed to take a new material from concept to FDA approval. [254 Pages, Hardcover]

Read More...

Glycobiology of the Immune Response

Rabinovich, Gabriel / Cobb, Brian / van Kooyk, Yvette — 3 Jul 2012 08:18:20 +0200

Carbohydrates are ubiquitous, essential molecules, as important as nucleic acids and proteins yet less well understood. Mounting data demonstrate that microbial and mammalian glycans and their protein-binding partners (lectins) play central roles in all innate and adaptive immune responses. Indeed, programmed remodeling of host glycans can modulate infection, autoimmunity, and cancer, while microbial glycoconjugates can serve as canonical innate receptor agonists that induce B cell and T cell activation. Glycobiology of the Immune Response explores the integration of state-of-the-art glycobiology and immunology to raise awareness of the multifaceted roles of glycans and lectins in the immune system NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.1111/(ISSN)1749-6632. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member. [252 Pages, Softcover]

Read More...

Handbook of Biophotonics

Popp, Jürgen / Tuchin, Valery V. / Chiou, Arthur / Heinemann, Stefan H. (eds.) — 14 Jun 2012 08:17:55 +0200

Adopting an application-related approach, these three volumes provide both the physics basics as well as the biological and medical background. This handbook collects interdisciplinary contributions, serving as a unique base of common knowledge and mutual understanding. [2350 Pages, Hardcover]

Read More...

Chemical Sensors and Biosensors

Lalauze, Rene — 13 Jun 2012 08:18:31 +0200

Interaction studies between chemical and biological species, in a gaseous or liquid state, and mineral or biological materials acting as sensitive elements, take a large place in this book. Electrical, electrochemical, piezoelectric and optical transducers taking place in detection mechanisms are also presented through developments and performances point of view. Micro reactors, nanotechnologies and flexible substrates, are taken in consideration in relation with neural networks. [Hardcover]

Read More...

Biomedical Imaging

Salzer, Reiner — 13 Jun 2012 08:17:39 +0200

This book presents and describes imaging technologies that can be used to study chemical processes and structural interactions in dynamic systems, principally in biomedical systems. The imaging technologies, largely biomedical imaging technologies such as MRT, Fluorescence mapping, raman mapping, nanoESCA, and CARS microscopy, have been selected according to their application range and to the chemical information content of their data. These technologies allow for the analysis and evaluation of delicate biological samples, which must not be disturbed during the profess. Ultimately, this may mean fewer animal lab tests and clinical trials. [448 Pages, Hardcover]

Read More...

Microcirculation Imaging

Leahy, Martin J. (ed.) — 7 Jun 2012 08:17:13 +0200

Adopting a multidisciplinary approach with input from physicists, researchers and medical professionals, this is the first handbook to give technical details while outlining the respective strengths and weaknesses of each imaging technique. [XVIII, 393 Pages, Hardcover]

Read More...

Polysaccharide Building Blocks

Habibi, Youssef / Lucia, Lucian — 30 Apr 2012 08:17:41 +0200

This text provides an archival reference for the evolving field of biomaterials and their applications in society, focusing on their composition, properties, characterization, chemistry and applications in bioenergy, chemicals, and novel materials and biomaterials. It has broad appeal due to the recently heightened awareness around bioenergy and biomass as potential replacements for petroleum feedstocks. The book is divided into three parts: cellulose-based biomaterials, chitin and chitosan biomaterials, and hemicelluloses and other polysaccharides. In the quest for a green economy, this book will inspire scientists towards novel sources for chemicals, materials, and energy. [430 Pages, Hardcover]

Read More...

Biomimetic, Bioresponsive, and Bioactive Materials

Santin, Matteo / Phillips, Gary J. (eds.) — 20 Apr 2012 08:17:11 +0200

The accessible introduction to biomaterials and their applications in tissue replacement, medical devices, and more Molecular and cell biology is being increasingly integrated into the search for high-performance biomaterials and biomedical devices, transforming a formerly engineering- and materials science-based field into a truly interdisciplinary area of investigation. Biomimetic, Bioresponsive, and Bioactive Materials presents a comprehensive introduction to biomaterials, discussing how they are selected, designed, and modified for integration with living tissue and how they can be utilized in the development of medical devices, orthopedics, and other related areas. Examining the physico chemical properties of widely used biomaterials and their uses in different clinical fields, the book explores applications including soft and hard tissue replacement; biointeractive metals, polymers, and ceramics; and in vitro, in vivo, and ex vivo biocompatibility tests and clinical trials. The book critically assesses the clinical level of research in the field, not only presenting proven research, but also positing new avenues of exploration. Biomimetic, Bioresponsive, and Bioactive Materials contains everything needed to get a firm grasp on materials science, fast. Written in an accessible style and including practice questions that test comprehension of the material covered in each chapter, the book is an invaluable tool for students as well as professionals new to the field. [248 Pages, Hardcover]

Read More...

Integrated Biomaterials in Tissue Engineering

18 Apr 2012 08:17:37 +0200

Integrated Biomaterials in Tissue Engineering features all aspects from fundamental principles to current technological advances in biomaterials at the macro/micro/nano/molecular scales suitable for tissue engineering and regenerative medicine. The book is unique as it provides all important aspects dealing with the basic science involved in structure and properties, techniques and technological innovations in material processing and characterizations, and applications of biomaterials in tissue engineering and regenerative medicine. [328 Pages, Hardcover]

Read More...

Replacing Animal Models

Davies, Jamie — 16 Apr 2012 08:17:59 +0200

Over the last decade, in vitro models have become more sophisticated and are at a stage where they can provide an effective alternative to in vivo experiments. Replacing Animal Models provides scientists and technicians with a practical, integrated guide to developing culture-based alternatives to in vivo experiments. The book is neither political nor polemical: it is technical, illustrating by example how alternatives can be developed and used and providing useful advice on developing others. After looking at the reasons for and potential benefits of alternatives to animal experiments, the book covers a range of methods and examples emphasising the design considerations that went into each system. The chapters also include 'case studies' that illustrate the ways in which culture models can be used to answer a range of important biological questions of direct relevance to human development, physiology, disease and healing. The thesis of this book is not that all animal experimentation can be replaced, now or in the near future, by equally effective or superior alternatives. Rather, the premise is that there is substantial opportunity, here and now, to do some common types of experiment better in vitro than in vivo, and that doing so will result in both scientific and ethical gains. [214 Pages, Hardcover]

Read More...

Handbook of Biophotonics

Popp, Jürgen / Tuchin, Valery V. / Chiou, Arthur / Heinemann, Stefan H. (eds.) — 5 Apr 2012 08:17:28 +0200

Intelligent Surfaces in Biotechnology

Textor, Marcus / Grandin, H. Michelle — 26 Mar 2012 08:17:26 +0200

This resource gives a comprehensive overview of surface modifications for applications in biotechnology using intelligent coatings. The coverage includes chemical properties, characterization methods, coating techniques, state-of-the-art examples, and an outlook on the promising future of this technology. It enables the interested materials scientist, chemist, or engineer to gain a comprehensive overview of the field, highlighting applications, with each chapter written by an expert in that particular area. Applications covered include tissue engineering, biotribology, drug targeting and delivery, wound healing, biosensors, nanopatterning, and bioinspired design of new smart materials and surfaces. [400 Pages, Hardcover]

Read More...

Analysis of Aggregates and Particles in Protein Pharmaceuticals

Mahler, Hanns-Christian / Jiskoot, Wim (eds.) — 26 Mar 2012 08:17:22 +0200

This book provides a comprehensive overview of methods used to quantify and characterize aggregates and particles. Analytical methods covered in the book include separation, light scattering, microscopy, and spectroscopy. Coverage begins with an introduction to aggregates and particles, followed by analytical methods related to soluble and insoluble aggregates based on emerging techniques. Subsequent chapters include spectroscopic techniques, UV/VIS, fluorescence, infrared and Ramen spectroscopy, and microscopic methods. Finally, the book discusses protein purification and formulation development. Featuring case studies illustrating methods and challenges, this book provides a necessary reference for protein pharmaceuticals. [464 Pages, Hardcover]

Read More...