Pratt's Essential Biochemistry, Global Edition
4. Auflage März 2018
728 Seiten, Softcover
Wiley & Sons Ltd
ISBN:
978-1-119-45112-9
John Wiley & Sons
Pratt's Essential Biochemistry, Global Edition aims to provide a solid foundation in biochemistry, presenting complete, up-to-date information while focusing on the practical aspects of biochemistry as it applies to human health, nutrition and disease. It presents a broad, but not overwhelming coverage of basic biochemical concepts that focus on the chemistry behind biology, structure-function relationships, transformation of energy and how genetic information is stored and made accessible. It relates these concepts to practical knowledge as well as providing many problem-solving opportunities to enhance skills.
PREFACE xi
Unit 1 Introduction
1 The Chemical Basis of Life 1
2 Aqueous Chemistry 24
Unit 2 Biomolecules: Structure and Functions
3 Flow of Genetic Information 52
4 Structure of Proteins 85
5 Functions of Proteins 119
6 How Enzymes Work 154
7 Enzyme Kinetics and Inhibition 183
8 Lipids and Biological Membranes 215
9 Transport Through Membrane 235
10 Biochemical Signaling 260
11 Carbohydrates 283
Unit 3 Metabolism
12 Metabolism and Bioenergetics 301
13 Glucose Metabolism 329
14 The Citric Acid Cycle 362
15 Oxidative Phosphorylation 385
16 Photosynthesis 411
17 Lipid Metabolism 432
18 Nitrogen Metabolism 464
19 Mammalian Fuel Metabolism: Regulation 497
Unit 4 Gene Replication and Expression
20 DNA Replication and Repair 519
21 Transcription and RNA 551
22 Synthesis of Proteins 580
GLOSSARY G-1
ODD-NUMBERED SOLUTIONS S-1
INDEX I-1
Unit 1 Introduction
1 The Chemical Basis of Life 1
2 Aqueous Chemistry 24
Unit 2 Biomolecules: Structure and Functions
3 Flow of Genetic Information 52
4 Structure of Proteins 85
5 Functions of Proteins 119
6 How Enzymes Work 154
7 Enzyme Kinetics and Inhibition 183
8 Lipids and Biological Membranes 215
9 Transport Through Membrane 235
10 Biochemical Signaling 260
11 Carbohydrates 283
Unit 3 Metabolism
12 Metabolism and Bioenergetics 301
13 Glucose Metabolism 329
14 The Citric Acid Cycle 362
15 Oxidative Phosphorylation 385
16 Photosynthesis 411
17 Lipid Metabolism 432
18 Nitrogen Metabolism 464
19 Mammalian Fuel Metabolism: Regulation 497
Unit 4 Gene Replication and Expression
20 DNA Replication and Repair 519
21 Transcription and RNA 551
22 Synthesis of Proteins 580
GLOSSARY G-1
ODD-NUMBERED SOLUTIONS S-1
INDEX I-1
Charlott Pratt received her Ph.D. in biochemistry from Duke University. She did post-doctoral research at the University of North Carolina at Chapel Hill and has contributed to numerous primary research articles and reviews. She is presently in the Department of Chemistry at Seattle Pacific University. She is co-author with Donald Voet and Judith Voet of Fundamentals of Biochemistry, also published by Wiley.
Kathleen Cornely received her Ph.D. in biochemistry from Cornell University. She has published numerous research articles and is presently Professor in the Department of Chemistry and Biochemistry at Providence College. She is a member of the Educational and Professional Development Committee of the American Society for Biochemistry and Molecular Biology and is on the editorial borad for the journal, Biochemistry and Molecular Biology Education.
Kathleen Cornely received her Ph.D. in biochemistry from Cornell University. She has published numerous research articles and is presently Professor in the Department of Chemistry and Biochemistry at Providence College. She is a member of the Educational and Professional Development Committee of the American Society for Biochemistry and Molecular Biology and is on the editorial borad for the journal, Biochemistry and Molecular Biology Education.
