Neuroprotective Natural Products
Clinical Aspects and Mode of Action
1. Edition April 2017
XXVI, 346 Pages, Hardcover
55 Pictures (9 Colored Figures)
Monograph
Short Description
The ideal companion for anyone actively researching means to prevent neurological disorders: Learn about origin, chemistry and mode of action of natural products that protect from Alzheimer's, Huntington's or Parkinson's disease.
Focusing on the molecular mechanisms of powerful naturally occurring agents and their implication for drug discovery, this timely book presents an overview of the most recent research advances in the field of bioactive natural products and natural drug formulations to combat today's destructive diseases.
To this extent, the authors discuss the most severe neurological disorders in our modern civilization, such as Alzheimer's, Parkinson's and Huntington's disease, as well as ischemic brain stroke and depression. The emerging diversity of active compounds is covered in detail, including flavonoids, cannabinoids and oleanolic acid, while experts in the field explain the chemistry, mode of action and clinical aspects of novel neuroprotective natural products. In each case, the benefits of treatments using natural products are addressed from the perspective of modern as well as traditional medicine.
With its multidisciplinary viewpoint, this is the ideal companion for medicinal and natural products chemists as well as neuroscientists, biochemists, pharmacologists, neurobiologists, and phytotherapists.
Neuroprotective agents: An overview on the general modes of action
Beneficial upshots of naturally occurring antioxidant compounds against neurological disorders
Natural neuroprotectives for the management of Parkinson's Disease
Neuroprotective effect of Ayurvedic preparations and natural products on Parkinson's disease
Lipid peroxidation and mitochondrial dysfunction in Alzheimer's and Parkinson's diseases: Role of natural products as cytoprotective agents
Anti-Alzheimer's agents from sea
Natural products against Huntington's disease: Implications of neurotoxic animal models and trangenics in preclinical studies
Possible role of neuroprotectants and natural products in epilepsy: Clinical aspects and mode of action
Neuroprotective effects of flavonoids in epilepsy
The role of noncompetitive antagonists of the N-methyl-D-aspartate (NMDA) receptors in treatment-resistant depression
Safety and efficacy of Ashwagandha (Withania somnifera)
Cannabinoids: A group of promising neuroprotective agents