|  | Guder, Walter G. / Narayanan, Sheshadri / Wisser, Hermann / Zawta, Bernd
Diagnostic Samples: From the Patient to the Laboratory
The Impact of Preanalytical Variables on the Quality of Laboratory Results
 4., aktualisierte Auflage - August 2009
67,90 Euro
2009. X, 114 Seiten, Hardcover
84 Abb. (84 Farbabb.), 32 Tab.
- Praktikerbuch -
ISBN 978-3-527-32307-4 - Wiley-VCH, Weinheim
Preis inkl. Mehrwertsteuer zzgl. Versandkosten.
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Ein internationales Autorenteam informiert Sie in diesem Band über verschiedenste Aspekte der Entnahme, des Transports, der Lagerung und der Präparation labormedizinischer Proben. Biologische und analytische Einflüsse und Wechselwirkungen werden ebenso diskutiert wir ein breites Spektrum von Variablen (Alter, Geschlecht, Rasse und Ernähungsgewohnheiten des Patienten, Schwangerschaft, Konsum von Drogen oder Stimulantien). Außerdem finden Sie Angaben zu nationalen und internationalen Standards aller Prozeduren, zur Probenidentifizierung, Sicherheit und Qualitätssicherung. Mit einem umfangreichen Tabellenanhang sowie einem Glossar!
Aus dem Inhalt
Dream and reality - An introductory case - The importance of the preanalytical phase
BIOLOGICAL INFLUENCES
Something unavoidable - Influences of age, gender, race and pregnancy
Changing habits - Influences that can vary (diet, starvation, exercise, altitude)
May I take coffee, smoke or drink before blood sampling? - Stimulants and addictive drugs as biological influence factors
What if I take herbs? - Effects of herbs on laboratory results
COLLECTION OF SPECIMEN
When to test? - Timing of sampling
Sampling during infusion therapy? - Sequence of diagnostic and therapeutic procedures
Sampling in the supine or upright position? - Effects of posture and tourniquet
What site for sampling blood? - Phlebotomy, arterial puncture and sampling from catheters
Blood from the skin - Capillary sampling
Did the lab mix up my sample? - Techniques of sample identification
A precious sample - Cerebrospinal fluid (CSF)
A sample that is nearly always available - Urine and saliva as diagnostic probes
Plasma or serum? - Differences to be considered
Take a lavender tube! - Additives and colour codes
TRANSPORT AND STORAGE
Fax me a sample - Effects of time and temperature during transport
Samples in transit - Legal standardization for mailing samples
How to keep a sample "fresh" - Storage of samples in the laboratory
PREPARATION OF SAMPLES FOR ANALYSIS
What has to be done on specimen arrival? - Specimen processing, centrifugation, distribution
Continuous or batchwise? - Preanalytical workflow and robotics
Safety aspects during the preanalytical phase - Disposal of specimens, needles, tubes and chemicals
SPECIAL ASPECTS WITH EACH ANALYTE
What is needed before blood transfusion? - Special aspects in immuno-haematology
Why a separate tube for the coagulation test? - Special aspects in haemostaseology
Blood cells are sensitive! - Special aspects in haematological analysis
Everything from a drop of blood? - Special aspects in clinical chemistry
Special tubes for hormones and proteomics? - Preanalytical factors in immunoassays
Blood cells can provide important information - Special aspects in cellular analysis
How to handle genes - Special aspects in molecular biology
When gases evaporate - Special aspects for blood gases and ionized calcium
The right time for drugs? - Special aspects in therapeutic drug monitoring (TDM)
Bacteria, fungi, parasites and viruses - Special aspects in microbiology
ENDOGENOUS AND EXOGENOUS INTERFERENCES
Can turbid samples be used? - Effects of lipaemia
A difficult case - Pitfalls with endogenous antibodies
The serum sample looks reddish - Effects of haemolysis
Does the laboratory have to know all my drugs? - Mechanisms and treatment of drug interference
Everything under control? - Quality assurance in the preanalytical phase
References
Glossary
Index
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