|  | Shioiri, Takayuki / Izawa, Kunisuke / Konoike, Toshiro (eds.)
Pharmaceutical Process Chemistry
 1. Edition October 2010
152.- Euro
2010. XXIV, 502 Pages, Hardcover
354 Fig., 48 Tab.
- Monograph -
ISBN 978-3-527-32650-1 - Wiley-VCH, Weinheim
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Content
Sample Chapter
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| Short description
Application-oriented and well structured, this monograph provides the essential knowledge on the basic chemistry needed for future development and key industrial techniques, as well as morphology, engineering and regulatory compliances.
From the contents
PART 1: INTRODUCTORY REMARKS
From Milligrams to Tons: The Importance of Synthesis & Process Research in the Development of New Drugs
PART 2: FUTURE APPLICATIONS
Design of Dynamic Salt Catalysts Based on Acid-Base Combination Chemistry
Asymmetric Oxidation with Hydrogen Peroxide, an Effective and Versatile Oxidant
New Methods for the Functionalization of Aromatic Compounds
Streamlining Synthesis via C-H Oxidation
Byproduct-Free C-C Bond Formation via Catalytic Hydrogenation and Transfer Hydrogenation
Enzymo-Metallic Dynamic Kinetic Resolution as a New Tool for Chiral Synthesis
Some Progress of Organic Synthesis of Pharmaceuticals in China
PART 3: USEFUL SYNTHTIC TECHNOLOGIES
Boron Reagents in Process Chemistry: Excellent Tools for Selective Reductions
Commercialization of a Sodium Hydride Mediated Arylation Process
An Entirely New Methodology for Synthesizing Perfluorinated Compounds
Application of Whole-Cell Biocatalysts in the Manufacture of Fine Chemicals
PART 4: CONSTRUCTION OF EFFICIENT PRACTICAL PROCESSES
Synthetic Studies on the Halichondrin B Analog, Eribulin Mesylate
Process Development of An Anthracycline Anticancer Drug
Process Development of HIV Integrase Inhibitor S-1360
An Efficient Synthesis of the PKC Inhibitor JTT-010
Practical Process Development of KRP-103 for Treatment of Urinary Incontinence
Development of a Novel Synthetic Method for RNA Oligomers
PART 5: USEFUL ENGINEERING TECHNOLOGIES
Process Research with Explosive Reactions
Novel Resolution Technologies Controlled by Effectively Designed Molecular Recognition Mechanism
Development on New Drug and Crystal Polymorph
Measurements and Mechanism of Drying of Active Pharmaceutical Ingredients
Matching Chemistry with Chemical Engineering for Optimum Design and Performance of Pharmaceutical Processing
Design Space for Drug Substance - the Approach used for Vandetanib
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