Boyd, Robert K. / Basic, Cecilia / Bethem, Robert A. Trace Quantitative Analysis by Mass Spectrometry
1. Edition - April 2008 89.90 Euro 2008. 748 Pages, Hardcover - Practical Approach Book - ISBN-10: 0-470-05771-8 ISBN-13: 978-0-470-05771-1 - John Wiley & Sons
Short description Quantitative Chemical Analysis by Mass Spectrometry provides a serious introduction to the subject of mass spectrometry, providing the reader with the tools and information to be well prepared to perform such demanding work in a real-life laboratory. This essential tool bridges several subjects and many disciplines including pharmaceutical, environmental and biomedical analysis that are utilizing mass spectrometry.
From the contents Preface.
Acknowledgements.
1 Measurement, Dimensions and Units.
2 Tools of the Trade I. The Classical Tools.
3 Tools of the Trade II. Theory of Chromatography.
Appendix 3.1 Derivation of the Plate Theory Equation for Chromatographic Elution.
Appendix 3.2 Transformation of the Plate Theory Elution Equation from Poisson to Gaussian Form.
Appendix 3.3 A Brief Introduction to Snyder's Theory of Gradient Elution.
List of Symbols Used in Chapter 3.
4 Tools of the Trade III. Separation Practicalities.
Appendix 4.1 Responses of Chromatographic Detectors: Concentration vs Mass-Flux Dependence.
5 Tools of the Trade IV. Interfaces and Ion Sources for Chromatography-Mass Spectrometry.
6 Tools of the Trade V. Mass Analyzers for Quantitation: Separation of Ions by m/z Values.
Appendix 6.1 Interaction of Electric and Magnetic Fields with Charged Particles.
Appendix 6.2 Leak Detection.
Appendix 6.3 List of Symbols Used in Chapter 6.
7 Tools of the Trade VI. Ion Detection and Data Processing.
8 Tools of the Trade VII: Statistics of Calibration, Measurement and Sampling.
Appendix 8.1 A Brief Statistics Glossary.
Appendix 8.2 Symbols Used in Discussion of Calibration Methods.
9 Method Development and Fitness for Purpose.
10 Method Validation and Sample Analysis in a Controlled Laboratory Environment.
