1. Edition - October 2009
162.- Euro
2009. XX, 429 Pages, Hardcover
10 Fig. (10 Colored Fig.)
- Handbook/Reference Book -
ISBN-10: 3-527-31661-2
ISBN-13: 978-3-527-31661-8 - Wiley-VCH, Weinheim






Content

Sample Chapter



Short description
The first overview on the molecular basis of drug resistance is a key resource for anyone working with antibiotics and cancer chemotherapeutics. Also of prime interest for biochemists and biophysicists, due to its systematic characterization of all known transporter classes.

From the contents
PART 1
1 The ABC Transporters: Structural Insights into Drug Transport
2 Biochemistry, Physiology, and Pharmacology of Nucleoside and Nucleobase Transporters
3 Organic Anion Transporting Polypeptides (Oatps/OATPs)
4 CNS Transporters as Drug Targets
PART 2
5 Bacterial Multidrug Transporters: Molecular and Clinical Aspects
6 Pleiotropic drug resistance in yeast and fungal pathogens
PART 3
7 QSAR studies on ABC-transporters: how to deal with polyspecificity
8 Drug Transporter Pharmacophores
PART 4
9 Biological Membranes and Drug Transport
10 Transport at the Blood-Brain Barrier
11 Bile canalicular transporters
12 Interplay of Cytochrome P450 Isoenzymes and ABC-transporter
13 ABC-Transporter: From target to antitarget
PART 3
14 A Systems Biology View of Drug Transporters
15 Drug Transporters in Health and Disease