|  | Sippl, Wolfgang / Jung, Manfred (eds.)
Epigenetic Targets in Drug Discovery
Methods and Principles in Medicinal Chemistry (Volume 42)
Edited by Mannhold, Raimund / Kubinyi, Hugo / Folkers, Gerd
 1. Edition - June 2009
139.- Euro
2009. XVI, 298 Pages, Hardcover
105 Fig. (15 Colored Fig.), 5 Tab.
- Handbook/Reference Book -
ISBN-10: 3-527-32355-4
ISBN-13: 978-3-527-32355-5 - Wiley-VCH, Weinheim
Content
Sample Chapter
Index
Detailed description
Fueled by the expertise of a team of international specialist authors, this first reference on the booming topic covers everything a drug researcher needs to know about targeting epigenetic mechanisms of disease.
The first part of the book surveys current methodologies for finding and validating drug candidates that act via epigenetic mechanisms. The second part systematically surveys known and suspected drug targets within the epigenetic machinery, including the discovery and development of vorinostat, the first marketed epigenetic drug.
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