|  | Kratz, Felix / Senter, Peter / Steinhagen, Henning (eds.)
Drug Delivery in Oncology
From Basic Research to Cancer Therapy
 1. Edition October 2011
449.- Euro
2011. 1690 Pages, 3 Volumes, Hardcover
600 Fig. (120 Colored Fig.), 50 Tab.
- Handbook/Reference Book -
ISBN 978-3-527-32823-9 - Wiley-VCH, Weinheim
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Sample Chapter
Index
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| Short description
The most comprehensive reference on the new generation of smart anticancer compounds discusses targeted delivery systems from antibodies to nanoparticles and controlled-release polymers. Essential reading for researchers and professionals in medical oncology and cancer biology.
From the contents
Volume 1:
PRINCIPLES OF TUMOR TARGETING
Limits of Conventional Cancer Chemotherapy
Pathophysiological and Vascular Characteristics of Tumors in Relation to Drug Delivery
Enhanced Permeability and Retention Effect in Relation to Tumor Targeting
Pharmacokinetics of Immunoglobulin G and Serum Albumin: Impact of the Neonatal Fc Receptor on Drug Design
Development of Cancer-Targeting Ligands and Ligand-Drug Conjugates
Antibody-Directed Enzyme Prodrug Therapy (ADEPT) - Basic Principles and its Practice So Far
TUMOR IMAGING
Imaging Techniques in Drug Development and Clinical Practice
Magnetic Nanoparticles in Magnetic Resonance Imaging and Drug Delivery
Preclinical and Clinical Tumor Imaging with SPECT/CT and PET/CT
Volume 2:
MACROMOLECULAR DRUG DELIVERY SYSTEMS
Antibody-Based Systems
Empowered Antibodies for Cancer Therapy
Mapping Accessible Vascular Targeting to Penetrate Organs and Solid Tumors
Considerations of Linker Technologies
Antibody-Maytansinoid Conjugates: From the Bench to the Clinic
Calicheamicin Antibody-Drug Conjugates and Beyond
Antibodies for the Delivery of Radionuclides
Bispecific Antibodies and Immune Therapy Targeting
POLYMER-BASED SYSTEMS
Design of Polymer-Drug Conjugates
Dendritic Polymers in Oncology: Facts, Features, and Applications
Site-Specific Prodrug Activation and the Concept of Self-Immolation
Ligand-Assisted Vascular Targeting of Polymer Therapeutics
Drug Conjugates with Poly(Ethylene)Glycole
Thermo-Responsive Polymers
Polysaccharide-Based Drug Conjugates for Tumor Targeting
Serum Proteins as Drug Carriers of Anticancer Agents
Future Trends, Challenges, and Opportunities with Polymer-Based Combination Therapy in Cancer
Clinical Experience with Drug-Polymer Conjugates
NANO- AND MICROPARTICULATE DRUG DELIVERY SYSTEMS - LIPID-BASED SYSTEMS
Overview on Nanocarriers as Delivery Systems
Development of PEGylated Liposomes
Immunoliposomes
Responsive Liposomes (for Solid Tumor Therapy)
Nanoscale Delivery Systems for Combination Chemotherapy
NANO- AND MICROPARTICULATE DRUG DELIVERY SYSTEMS - POLYMER-BASED SYSTEMS
Micellar Strcutures as Drug Delivery Systems
Tailor-Made Hydrogels for Tumor Delivery
pH-Triggered Micelles for Tumor Delivery
Albumin-Drug Nanoparticles
Carbon Nanotubes
Volume 3:
LIGAND-BASED DRUG DELIVERY SYSTEMS
Cell-Penetrating Peptides in Cancer Targeting
Targeting to Peptide Receptors
Aptamer Conjugates: Emerging Delivery Platforms for Targeted Cancer Therapy
Design and Synthesis of Drug Conjugates of Vitamins and Growth Factors
Drug Conjugates with Polyunsaturated Fatty Acids
SPECIAL TOPICS
RNA Drug Delivery Approaches
Local Gene Delivery for Therapy of Solid Tumors
Viral Vectors for RNA Interference Applications in Cancer Research and Therapy
Design of Targeted Protein Toxins
Drug Targeting to the Central Nervous System
Liver Tumor Targeting
Photodynamic Therapy: Photosensitizers Targeting and Delivery
Tumor-Targeting Strategies with Anticancer Platinum Complexes
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