|  | Lednicer, Daniel
The Organic Chemistry of Drug Synthesis, Volume 7
Organic Chemistry Series of Drug Synthesis (Volume 7)
 November 2007
132.- Euro
2007. 272 Pages, Hardcover
ISBN 978-0-470-10750-8 - John Wiley & Sons
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| Detailed description
The classic reference on the synthesis of medicinal agents --now completely updated
The seventh volume in the definitive series that provides a quick yet thorough overview of the synthetic routes used to access specific classesof therapeutic agents, this volume covers approximately 220 new non-proprietary drug entities introduced since the publication of Volume 6.Many of these compounds represent novel structural types firstidentified by sophisticated new cell-based assays. Specifically, a significant number of new antineoplastic and antiviral agents are covered.
As in the previous volumes, materials are organized by chemical class and syntheses originate with available starting materials. Organized to make the information accessible, this resource covers disease state, rationale for method of drug therapy, and the biological activities of each compound and preparation. The Organic Chemistry of Drug Synthesis, Volume 7 is a hands-on reference for medicinal and organic chemists, and a great resource for graduate and advanced undergraduate students in organic and medicinal chemistry.
From the contents
Preface.
1 OPEN-CHAIN COMPOUNDS.
1. Human Immunodeficiency Virus.
2. Human Rhinovirus.
2 ALICYCLIC COMPOUNDS.
1. Monocyclic Compounds.
2. Polycyclic Compounds: Steroids.
3. Polycyclic Compounds.
3 MONOCYCLIC AROMATIC COMPOUNDS
1. Arylcarbonyl Derivatives.
2. Biphenyls.
3. Compounds Related to Aniline.
4. Compounds Related to Arylsulfonic Acids.
5. Diarylmethanes.
6. Miscellaneous Monocyclic Aromatic Compounds.
4 CARBOCYCLIC COMPOUNDS FUSED TO A BENZENE RING.
1. Indenes.
2. Naphthalenes.
3. Tetrahydronaphthalenes.
4. Other benzofused carbocyclic compounds.
5 FIVE-MEMBERED HETEROCYCLES.
1. Compounds with One Heteroatom.
2. Compounds with Two Heteroatoms.
6 SIX-MEMBERED HETEROCYCLES.
1. Compounds with One Heteroatom.
2. Compounds with Two Heteroatoms.
7 FIVE-MEMBERED HETEROCYCLES FUSED TO ONE BENZENE RING.
1. Compounds with One Heteroatom.
2. Five-Membered Rings with Two Heterocyclic Atoms.
8 SIX-MEMBERED HETEROCYCLES FUSED TO ONE BENZENE RING.
1. Compounds with One Heteroatom.
2. Compounds with Two Heteroatoms.
9 BICYCLIC FUSED HETEROCYCLES.
1. Compounds with Five-Membered Rings Fused to Six-Membered Rings.
2. Compounds with Two Fused Six-Membered Rings.
3. Miscellaneous Compounds with Two Fused Heterocyclic Rings: Beta Lactams.
10 POLYCYCLIC FUSED HETEROCYCLES.
1. Compounds with Three Fused Rings.
2. Compounds with Four Fused Rings.
3. Compounds with Five or More Fused Rings: Camptothecins.
References.
Subject Index.
Cross Index of Biological Activity.
Cumulative Index.
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