1. Edition - April 2008
129.- Euro
2008. 500 Pages, Hardcover
- Textbook -
ISBN-10: 0-470-75883-X
ISBN-13: 978-0-470-75883-0 - John Wiley & Sons






Sample Chapter

Short description
This workbook accompanies Organic Synthesis: Strategy and Control, the bestselling advanced organic chemistry textbook. The workbook provides a complete course for advanced organic chemistry students and includes a graded set of problems, solutions, and discussions to illustrate and develop the themes of each of the chapters in the textbook.

From the contents
Section A: Introduction: Selectivity

1. Planning Organic Syntheses: Tactics, Strategy and Control

2. Chemoselectivity

3. Regioselectivity: Controlled Aldol Reactions

4. Stereoselectivity: Stereoselective Aldol Reactions

5. Alternative Strategies for Enone Synthesis

6. Choosing a Strategy: The Synthesis of Cyclopentenones

Section B: Making Carbon-Carbon Bonds

7. The Ortho Strategy for Aromatic Compounds

8. s-Complexes of Metals

9. Controlling the Michael Reaction

10. Specific Enol Equivalents

11. Extended Enolates

12. Allyl Anions

13. Homoenolates

14. Acyl Anion Equivalents

Section C: Carbon-Carbon Double Bonds

15. Synthesis of Double Bonds of Defined Stereochemistry

16. Vinyl Anions

17. Electrophilic Attack on Alkenes

18. Vinyl Cations

19. Allyl Alcohols: Allyl Cation Equivalents (and More)

Section D: Stereochemistry

20. Control of Stereochemistry -- Introduction

21. Diastereoselectivity

22. Resolution

23. The Chiral Pool: Asymmetric Synthesis with Natural Products as Starting Materials

24. Asymmetric Induction I: Reagent-Based Strategy

25. Asymmetric Induction II: Asymmetric Catalysis: Formation of C-O and C-N Bonds

26. Asymmetric Induction III: Asymmetric Catalysis: Formation of C-H and C-C Bonds

27. Asymmetric Induction IV: Substrate-Based Strategy

28. Kinetic Resolution

29. Enzymes: Biological Methods in Asymmetric Synthesis

30. New Chiral Centres from Old: Enantiomerically Pure Compounds & Sophisticated Syntheses

31. Strategy of Asymmetric Synthesis

Section E: Functional Group Strategy

32. Functionalisation of Pyridine

33. Oxidation of Aromatic Rings and of Enol(ate)s

34. Functionality and Pericyclic Reactions: Nitrogen Heterocycles by Cycloadditions and Sigmatropic Rearrangements

35. Synthesis and Chemistry of Azoles and other Heterocycles with Two or more Heteroatoms

36. Tandem Organic Reactions