Mayer, R. John / Ciechanover, Aaron J. / Rechsteiner, Martin (eds.) Protein Degradation Vol. 2: The Ubiquitin-Proteasome System Protein Degradation (Volume 2)
1. Edition - December 2005 169.- Euro 2005. XIV, 286 Pages, Hardcover 78 Fig. (25 Colored Fig.), 5 Tab. - Handbook/Reference Book - ISBN-10: 3-527-31130-0 ISBN-13: 978-3-527-31130-9 - Wiley-VCH, Weinheim
Short description The second volume in a new series, this book discusses the mechanism and cellular functions of targeted protein breakdown via the ubiquitin pathway. Required reading for molecular biologists, cell biologists and physiologists with an interest in protein degradation.
From the contents Degrons: signals and sites for ubiquitylation The proteasome portal and regulation of proteolysis PAN and the proteasome Ubiquitin domain proteins MEKK1: dual function as a protein kinase and a ubiquitin protein ligase HECT domain ubiquitin protein ligases UCRP: ubiquitin cross-reactive protein SUMOs and their function in the cell Functions of the ubiquitin-proteasome pathway Molecular Chaperones and the ubiquitin/proteasome system Dissecting intracellular proteolysis using small molecule inhibitors and molecular probes Electron microscopy of compartmentalised proteases Molecular dissection of autophagy in yeast
