1. Edition - March 2009
142.- Euro
2009. XXI, 362 Pages, Hardcover
11 Fig. (8 Colored Fig.), 16 Tab. 
- Handbook/Reference Book -
ISBN-10: 3-527-32084-9
ISBN-13: 978-3-527-32084-4 - Wiley-VCH, Weinheim






Content

Sample Chapter

Index



Short description
This very first comprehensive resource on the topic covers basic knowledge, identification technologies as well as examples of successful clinical application. A must-have for biologists and oncologists in science, clinics and industry.

From the contents
TUMOUR-ASSOCIATED ANTIGENS (TAAS): SUBCLASSES OF TAAS
T cell Antigens in Cancer (A. Paschen)
Human Tumour Antigens, Immunosurveillance, and Cancer Vaccines (O.J. Finn)
METHODS TO DETECT TAAS
Humoral Antigens in Cancer: Serological Identification Methods, Part I: SEREX (M. Pfreundschuh)
Humoral Antigens in Cancer: Serological Identification Methods, Part II: Proteomex and AMIDA (B. Seliger, O. Gires)
cDNA and Microarray-Based Technologies (F. Marincola, Ena Wang)
Detection and Identification of TAA by SELDI-TOF (F. von Eggeling, C. Melle)
TAAS AND THEIR USEFULNESS
Minor Histocompatibility Antigens and TAAs for Pediatric Cancers (U. Behrends, J. Mautner)
TAAs and their Regulation/Epigenetics (M. Maio)
Cancer-Testis Antigens (CT-antigens) (J.S. Cebon)
Animal Models for TAAs (P. McLaughlin)
Epithelial Cell Adhesion Molecule EpCAM in cancer (CD326) (P.A Baeuerle, G. Riethmüller)
Carcinoembryonic Antigen CEA (W. Zimmermann, R. Kammerer)
Her2/neu and Herceptin (B. Seliger)
Epstein-Barr Virus (EBV) Tumour-Associated Antigens (C. Mancao, W. Hammerschmidt)
Human Papilloma Virus (HPV) Tumour-Associated Antigens (A. Kaufmann)
Circulating TAAs: Biomarkers for Ovarian Cancer Diagnosis (E. Seregni, E. Bombardieri)
CLINICAL APPLICATIONS OF TAAS
Cancer Vaccines (A. Dalgleish)
Peptide Vaccination (D.P. Fairlie)
DNA Vaccination: Human Papilloma Virus (T.C. Wu)
Adoptive T cell transfer (A. Moosmann, A. Krackhardt)