1. Edition - February 2006
319.- Euro
2006. XXXII, 742 Pages, 2 Volumes, Hardcover
132 Fig. (33 Colored Fig.), 19 Tab. 
- Handbook/Reference Book -
ISBN-10: 3-527-31088-6
ISBN-13: 978-3-527-31088-3 - Wiley-VCH, Weinheim






Sample Chapter



Short description
Covering information dealing with the latest blood-brain interface research, this first handbook to combine the various structural and functional features involved in the regulation of brain perfusion and neuronal function highlights pharmacological and biomedical applications.


From the contents
Introductory Preface: The blood-brain interfaces: An integrated concept (R. Dermietzel, D. Spray, M. Nedergaard)
ONTOGENY OF THE BLOOD-BRAIN-BARRIER
Development of the Blood-Brain Interface (B. Engelhardt)
Brain Angiogenesis and Barrier Genesis (K.-W. Kim)
Microvascular Influences on Progenitor Cell Mobilization and Fate in the Adult Brain (S. Goldman)
THE CELLS OF THE BLOOD-BRAIN INTERFACE: REVISITED
The endothelial frontier (H. Wolburg)
Pericytes and their contribution to the blood-brain-barrier (M. Ramsauer)
Brain Macrophages: Enigmas and Conundrums (G.I. Hatton)
The microglial component (I. Bechmann)
The bipolar astrocyte (J. Abbott)
Responsive astrocytic endfeet: the role of AQP4 in BBB development and functioning (A. Frigeri
HORMONAL AND ENZYMATIC CONTROL OF BRAIN VESSELS
The Role of Fibroblast Growth Factor 2 in Establishment and Maintenance
of the Blood-brain Barrier (B. Reuss)
Cytokine interaction with the blood-brain-barrier (W. Pan)
Insulin and the blood-brain barrier (W.A. Banks)
Glucocorticoid Hormones and Estrogens: Their Interaction with the Endothelial Cells of the Blood-Brain Barrier (J.-B. Dietrich)
Metalloproteases and the brain microvasculature (D. Krause)
CULTURING THE BLOOD BRAIN BARRIER
Culturing the blood-brain-barrier (R. Cecchelli)
Induction of blood-brain barrier properties in cultured endothelial cells (H.-J. Galla)
Artificial blood brain barriers (D. Janigro)
In silico prediction models for blood-brain barrier permeation (G. Ecker)
DRUG DELIVERY TO THE BRAIN
The Blood-Brain Barrier: Roles of the Multidrug Resistance Transporter P-Glycoproteon (R. Beliveau)
Targeting of neuropharmaceuticals by chemical delivery (N. Bodor)
Drug Delivery to the Brain by Internalizing Receptors at the Blood-Brain Barrier (A.G. de Boer)
VASCULAR PERFUSION
Blood-Brain Transfer and Metabolism of Oxygen (A. Gjedde)
Functional Brain Imaging (G. Dienel)
DISEASE-RELATED RESPONSE
Inflammatory response of the blood-brain interface (P. Faustmann)
Stroke and the Blood-Brain Interface (M.J. Cipolla)
Diabetes and the consequences for the blood-brain barrier (A.D. Mooradian)
Human parasitic disease in the context of the blood-brain-barrier - Effects, interactions, and transgression (D.A. Milner)
The healthy and diseased retina-blood interfaces (T. Chan-Ling)