1. Edition - November 2002
329.- Euro
2002. 862 Pages, Hardcover
ISBN-10: 0-471-49560-3
ISBN-13: 978-0-471-49560-4 - John Wiley & Sons








Short description
This comprehensive reference provides an up-to-date introduction to the key issues relating to the production and application of radiopharmaceuticals. The book covers a wide range of radiochemistry and clinical applications including the production of various radionuclides, positron emission tomography (PET) and drug development. Discussions on the uses of radiopharmaceuticals in the diagnosis and therapy of cancer and other diseases are also included.

From the contents
Foreword.

Production of Radionuclides in Accelerators (Schlyer).

Accelerators available for Isotope Production (Ruth).

Reactor Production of Radionuclides (Mausner and Mirzadeh).

Chemistry of Nitrogen-13 and Oxygen-15 (Clark and Aigbirhio).

Aspects of the Synthesis of 11C-Labelled Compounds (Antoni et al).

Chemistry of Fluorine-18 Radiopharmaceuticals (Snyder and Kilbourn).

Production and Application of Synthetic Precursors Labeled with Carbon-11 and Fluorine-18 (Ferrieri).

Automation for the Synthesis and Application of PET Radiopharmaceuticals (Alexoff).

Design and Synthesis of 2-Deoxy-2-[18F]Fluoro-D-Glucose (18FDG) (Fowler and Ido).

Technetium Radiopharmaceuticals (Mahmood and Jones).

Chemistry of Gallium and Indium Radiopharmaceuticals (Weiner and Thakur).

Chemistry of Copper Radionuclides and Radiopharmaceutical Products (Anderson et al).

Chemistry applied to Iodine Radionuclides (Finn).

Radiobromine for Imaging and Therapy (Rowland et al).

Development of Radiolabeled Probes to monitor Gene Therapy (Shiue and Eck).

Mechanisms of Target Specific Uptake using Examples of Muscarinic Receptor Binding Radiotracers (Eckelman).

Strategies for quantifying PET Imaging Data from Tracer Studies of Brain Receptors and Enzymes (Logan).

Radiopharmaceuticals for studying the Heart (Hwang and Bergmann).

PET Imaging Studies in Drug Abuse Research (Fowler et al).

Research and Clinical Application of Neuroreceptor Imaging (Wagner and Szabo).

Dynamic Neurotransmitter Interactions measured with PET (Schiffer and Dewey).

Tumor Imaging (Hustinx and Alavi).

Radiolabeled Peptides for Tumor Imaging (Knight).

Radiolabeled Anitbodies for Tumor Imaging and Therapy (Zalutsky and Lewis).

Receptor Imaging of Tumors (Non-peptide) (Katzenellenbogen).

Pulmonary Function Imaging with PET Radiopharmaceuticals (Elsinga and Vaalburg).

Considerations in the Selection of Radionuclides for Cancer Therapy (Kassis and Adelstein).

Radiopharmaceuticals for the Study of Liver and Renal Function (Vera et al).