Short description Cross-over trials are experiments in which subjects, whether patients or healthy volunteers, are each given a number of treatments with the object being to study the differences between these treatments. They are used extensively in clinical research, particularly in the early phases of drug development. Cross-over Trials in Clinical Research, Second Edition has been fully updated to include the latest methodology used in the design and analysis of cross-over trials.
From the contents Preface to the Second Edition.
Preface to the First Edition.
1. Introduction.
2. Some Basic Considerations Concerning Estimation in Clinical Trials.
3. The AB/BA Design with Normal Data.
4. Other Outcomes and the AB/BA Design.
5. Normal Data from Designs with Three or More Treatments.
6. Other Outcomes from Designs with Three or More Treatments.
7. Some Special Designs.
8. Graphical and Tabular Presentation of Cross-over Trials.
