Short description Meta-analysis is one of the main statistical methods used in clinical trials. Previous accounts of meta-analysis have given the impression that the topic is a series of separate techniques. This book provides a unified approach, developing the subject from mathematical theory through to practical discussions of implementation.
From the contents Introduction
Protocol development
Estimating the treatment difference in an individual trial
Combining estimates of a treatment difference across trials
Meta-analysis using individual patient data
Dealing with heterogeneity
Presentation and interpretation of results
Selection bias
Dealing with non-standard datasets
Inclusion of trials with different study designs
A Bayesian approach to meta-analysis
Sequential methods for meta-analysis
Appendix Methods of estimation and hypothesis testing
