Chemistry articles from Wiley-VCH/ChemPubSoc Europe

Opening Up the World of Chemistry

2012-01-02T:+05:00

[Editorial]

ChemistryOpen, January 2, 2012, DOI: 10.1002/open.201100009. Read article.

Determining the Role of the Aromatic Ring of N-Arylmethyl ent-conduramine F-1 in their Interactions with α-Glucosidases by Saturation Transfer Difference NMR Spectroscopy Experiments

2012-01-02T:+05:00

Saturation transfer difference (STD) NMR spectroscopy was used to study the role of aromatic moieties in the inhibition of α-glucosidases by N-arylmethyl ent-conduramine F-1. STD epitope mapping and molecular docking simulations provide new insights into the structure-based design of drugs targeting this enzyme (see figure).

[Communication]
Antonio Hernández Daranas, Sonia Koteich Khatib, Robert Lysek, Pierre Vogel, José A. Gavín
ChemistryOpen, January 2, 2012, DOI: 10.1002/open.201100004. Read article.

Semi-Synthesis and Analysis of Chemically Modified Zif268 Zinc-Finger Domains

2012-01-02T:+05:00

The entire zinc-finger domain of Zif268 was synthesized by a semi-synthetic pathway using the expressed protein ligation approach. Despite several modifications, for example, attachment of a fluorophore and introduction of a metal-chelating amino acid within the sequence of the third zinc finger, circular dichroism spectroscopic measurements confirmed zinc-induced folding and intact DNA binding ability.

[Full Paper]
Friederike Fehr, André Nadler, Florian Brodhun, Ivo Feussner, Ulf Diederichsen
ChemistryOpen, January 2, 2012, DOI: 10.1002/open.201100002. Read article.

Ti/Ni-Based Multimetallic System for the Efficient Allylation of Carbonyl Compounds

2012-02-03T:+05:00

[Short Communication]
Angela Martínez-Peragón, Alba Millán, Araceli G. Campaña, Irene Rodríguez-Márquez, Sandra Resa, Delia Miguel, Luis Alvarez de Cienfuegos, Juan M. Cuerva
Eur. J. Org. Chem., February 3, 2012, DOI: 10.1002/ejoc.201101842. Read article.

Oxidative Homologation of Aldehydes to α-Ketoaldehydes by using Iodoform, o-Iodoxybenzoic Acid, and Dimethyl Sulfoxide

Andrea Zall, Dennis Bensinger, Boris Schmidt — 2012-01-24T:+05:00

[Full Paper]
Andrea Zall, Dennis Bensinger, Boris Schmidt
Eur. J. Org. Chem., January 24, 2012, DOI: 10.1002/ejoc.201101835. Read article.

Replacement of HMPA in Samarium Diiodide Promoted Cyclizations and Reactions of Organolithium Compounds
Dedicated to Professor Dr. Gerhard Erker on the occasion of his 65th birthday

2012-01-25T:+05:00

[Short Communication]
Mathias Berndt, Alexandra Hölemann, André Niermann, Christoph Bentz, Reinhold Zimmer, Hans-Ulrich Reissig
Eur. J. Org. Chem., January 25, 2012, DOI: 10.1002/ejoc.201101830. Read article.

New Linearly and Angularly Fused Quinazolinones: Synthesis through Gold(I)-Catalyzed Cascade Reactions and Anticancer Activities

2012-02-06T:+05:00

[Full Paper]
Nitin T. Patil, Pediredla G. V. V. Lakshmi, Balasubramanian Sridhar, Sujata Patra, Manika Pal Bhadra, Chitta Ranjan Patra
Eur. J. Org. Chem., February 6, 2012, DOI: 10.1002/ejoc.201101822. Read article.

Synthesis of Isoxazole Triflones

Hiroyuki Kawai, Yutaka Sugita, Etsuko Tokunaga, Norio Shibata — 2012-01-25T:+05:00

[Short Communication]
Hiroyuki Kawai, Yutaka Sugita, Etsuko Tokunaga, Norio Shibata
Eur. J. Org. Chem., January 25, 2012, DOI: 10.1002/ejoc.201101814. Read article.

Stereocontrolled Synthesis of the cis-Hydroxydecalin System: Towards Biologically Active 19-nor-Clerodanes

Paul Malek Mirzayans, Rebecca H. Pouwer, Craig M. Williams, Paul V. Bernhardt — 2012-01-26T:+05:00

[Full Paper]
Paul Malek Mirzayans, Rebecca H. Pouwer, Craig M. Williams, Paul V. Bernhardt
Eur. J. Org. Chem., January 26, 2012, DOI: 10.1002/ejoc.201101807. Read article.

Asymmetric Organocatalytic Michael Addition–Cyclization Cascade Reaction of Nitroalkanes with o-Hydroxycinnamaldehydes

Kwang-Su Choi, Sung-Gon Kim — 2012-01-13T:+05:00

[Short Communication]
Kwang-Su Choi, Sung-Gon Kim
Eur. J. Org. Chem., January 13, 2012, DOI: 10.1002/ejoc.201101794. Read article.

Phomopsinones A–D: Four New Pyrenocines from Endophytic Fungus Phomopsis sp.
Biologically Active Secondary Metabolites from Fungi, 51. Part 50: I. N. Siddiqui, A. Zahoor, H. Hussain, I. Ahmed, V. U. Ahmad, D. Padula, S. Draeger, B. Schulz, K. Meier, M. Steiner, T. Kurtan, U. Flörke, G. Pescitelli, K. Krohn, J. Nat. Prod. 2011, 74, 365–373.

2012-02-01T:+05:00

[Full Paper]
Hidayat Hussain, Karsten Krohn, Ishtiaq Ahmed, Siegfried Draeger, Barbara Schulz, Sebastiano Di Pietro, Gennaro Pescitelli
Eur. J. Org. Chem., February 1, 2012, DOI: 10.1002/ejoc.201101788. Read article.

Solvent-Free Tandem Synthesis of 2-Thiazolines and 2-Oxazolines Catalyzed by a Copper Catalyst

2012-02-03T:+05:00

[Full Paper]
Xiangnan Li, Baoyue Zhou, Jin Zhang, Mengyao She, Shujuan An, Haixia Ge, Cong Li, Bing Yin, Jianli Li, Zhen Shi
Eur. J. Org. Chem., February 3, 2012, DOI: 10.1002/ejoc.201101786. Read article.

Practical Synthesis of Unsymmetrical Diarylacetylenes from Propiolic Acid and Two Different Aryl Bromides

Stefano Tartaggia, Ottorino De Lucchi, Lukas J. Gooßen — 2012-01-18T:+05:00

[Full Paper]
Stefano Tartaggia, Ottorino De Lucchi, Lukas J. Gooßen
Eur. J. Org. Chem., January 18, 2012, DOI: 10.1002/ejoc.201101770. Read article.

Asymmetric Michael Addition Reactions between 3-Substituted Benzofuran-2(3H)-ones and 1,1-Bis(phenylsulfonyl)ethylene Catalyzed by Bifunctional Catalysts Containing Tertiary Amine and Thiourea Groups

2012-02-06T:+05:00

[Full Paper]
Xin Li, Yue-Yan Zhang, Xiao-Song Xue, Jia-Lu Jin, Bo-Xuan Tan, Cong Liu, Nan Dong, Jin-Pei Cheng
Eur. J. Org. Chem., February 6, 2012, DOI: 10.1002/ejoc.201101765. Read article.

Bis- and Tris-Alkyne Phosphoramidites for Multiple 5'-Labeling of Oligonucleotides by Click Chemistry

Caroline Ligeour, Albert Meyer, Jean-Jacques Vasseur, François Morvan — 2012-02-06T:+05:00

[Full Paper]
Caroline Ligeour, Albert Meyer, Jean-Jacques Vasseur, François Morvan
Eur. J. Org. Chem., February 6, 2012, DOI: 10.1002/ejoc.201101763. Read article.

Development of a Solid-Phase Approach to the Natural Product Class of Ahp-Containing Cyclodepsipeptides

Sara C. Stolze, Michael Meltzer, Michael Ehrmann, Markus Kaiser — 2012-01-23T:+05:00

[Full Paper]
Sara C. Stolze, Michael Meltzer, Michael Ehrmann, Markus Kaiser
Eur. J. Org. Chem., January 23, 2012, DOI: 10.1002/ejoc.201101757. Read article.

Synthesis of Modified Phenylalanine Peptides by Cross Enyne Metathesis and a Diels–Alder Reaction as Key Steps

2012-02-03T:+05:00

[Full Paper]
Sambasivarao Kotha, Deepti Goyal (née Bansal), Niranjan Thota, Venu Srinivas
Eur. J. Org. Chem., February 3, 2012, DOI: 10.1002/ejoc.201101744. Read article.

Asymmetric Allylboration of Aldehydes with Pinacol Allylboronates Catalyzed by 1,1'-Spirobiindane-7,7'-diol (SPINOL) Based Phosphoric Acids

2012-01-16T:+05:00

[Short Communication]
Chun-Hui Xing, Yuan-Xi Liao, Yimei Zhang, Darya Sabarova, Monica Bassous, Qiao-Sheng Hu
Eur. J. Org. Chem., January 16, 2012, DOI: 10.1002/ejoc.201101739. Read article.

A One-Pot Three-Step Synthesis of Z-Trisubstituted Olefins from Arylalkynes and Their Cyclization into 4-Aryl-2H-chromenes

2012-01-20T:+05:00

[Full Paper]
Evelia Rasolofonjatovo, Bret Tréguier, Olivier Provot, Abdallah Hamze, Jean-Daniel Brion, Mouâd Alami
Eur. J. Org. Chem., January 20, 2012, DOI: 10.1002/ejoc.201101735. Read article.

Asymmetric Benzoylation of meso-Hydrobenzoin Using a Reusable Tripodal Imidazoline–Pyridine–Cu Catalyst

Takayoshi Arai, Ken Sakagami — 2012-01-17T:+05:00

[Short Communication]
Takayoshi Arai, Ken Sakagami
Eur. J. Org. Chem., January 17, 2012, DOI: 10.1002/ejoc.201101722. Read article.

A Novel Type of Chiral Triangulane-Based Diphosphane Ligands for Transition Metals
See ref.¹

2012-01-31T:+05:00

[Full Paper]
Alexander F. Khlebnikov, Sergei I. Kozhushkov, Dmitry S. Yufit, Heiko Schill, Michael Reggelin, Volker Spohr, Armin de Meijere
Eur. J. Org. Chem., January 31, 2012, DOI: 10.1002/ejoc.201101715. Read article.

Cicindeloine from Stenus cicindeloides – Isolation, Structure Elucidation, and Total Synthesis

2012-02-03T:+05:00

[Full Paper]
Tobias Müller, Matthias Göhl, Inka Lusebrink, Konrad Dettner, Karlheinz Seifert
Eur. J. Org. Chem., February 3, 2012, DOI: 10.1002/ejoc.201101709. Read article.

Synthesis of a Photochromic Fused 2H-Chromene Capable of Generating a Single Coloured Species

2012-02-06T:+05:00

[Full Paper]
Céu M. Sousa, João Pina, João Seixas de Melo, Jerome Berthet, Stephanie Delbaere, Paulo J. Coelho
Eur. J. Org. Chem., February 6, 2012, DOI: 10.1002/ejoc.201101702. Read article.

A Photodynamic Library of Tetrasulfinylcalix[4]arenes: The Sulfinyl Dance

2012-01-11T:+05:00

[Full Paper]
Roberta Cacciapaglia, Stefano Di Stefano, Osvaldo Lanzalunga, Leonardo Maugeri, Marco Mazzonna
Eur. J. Org. Chem., January 11, 2012, DOI: 10.1002/ejoc.201101699. Read article.

Klebsiella pneumoniae (NBRC 3319) Mediated Asymmetric Reduction of α-Substituted β-Oxo Esters and Its Application to the Enantioiselective Synthesis of Small-Ring Carbocycle Derivatives

Rajib Bhuniya, Tridib Mahapatra, Samik Nanda — 2012-01-30T:+05:00

[Full Paper]
Rajib Bhuniya, Tridib Mahapatra, Samik Nanda
Eur. J. Org. Chem., January 30, 2012, DOI: 10.1002/ejoc.201101695. Read article.

The Oxy-Cope Rearrangement of Aldol Products. A Combined Experimental and Theoretical Study

Christian F. Weise, Stefan Immel, Frank Richter, Christoph Schneider — 2012-01-27T:+05:00

[Full Paper]
Christian F. Weise, Stefan Immel, Frank Richter, Christoph Schneider
Eur. J. Org. Chem., January 27, 2012, DOI: 10.1002/ejoc.201101690. Read article.

Stereoselective Olefination and Regiospecific Vicinal Difunctionalization of Imines with α-(Benzothiazol-2-ylsulfonyl) Carbonyl Compounds

You-Dong Shao, Xue-Song Wu, Shi-Kai Tian — 2012-01-26T:+05:00

[Full Paper]
You-Dong Shao, Xue-Song Wu, Shi-Kai Tian
Eur. J. Org. Chem., January 26, 2012, DOI: 10.1002/ejoc.201101684. Read article.

Total Synthesis of (+)-Aspicilin by an Alkyne-Based Approach and Its Biological Evaluation

Chada Raji Reddy, Nagavaram Narsimha Rao, Pombala Sujitha, Chityal Ganesh Kumar — 2012-02-03T:+05:00

[Full Paper]
Chada Raji Reddy, Nagavaram Narsimha Rao, Pombala Sujitha, Chityal Ganesh Kumar
Eur. J. Org. Chem., February 3, 2012, DOI: 10.1002/ejoc.201101673. Read article.

Palladium-Catalyzed Tandem Reactions of β-(2-Bromophenyl)-α,β-Unsaturated Carbonyl Compounds with 2-Hydroxyphenylboronic Acid: A New Route to Benzo[c]chromenes

Qihua Zhu, Xuyan Wang, Yungen Xu — 2012-01-16T:+05:00

[Short Communication]
Qihua Zhu, Xuyan Wang, Yungen Xu
Eur. J. Org. Chem., January 16, 2012, DOI: 10.1002/ejoc.201101670. Read article.

Synthesis of 6-Substituted 2(1H)-Pyridon-3-yl C-2'-Deoxyribonucleosides

2012-02-03T:+05:00

[Full Paper]
Hubert Chapuis, Tomáš Kubelka, Nicolas Joubert, Radek Pohl, Michal Hocek
Eur. J. Org. Chem., February 3, 2012, DOI: 10.1002/ejoc.201101662. Read article.

An Efficient Route to Quinolines and Other Compounds by Iron-Catalysed Cross-Dehydrogenative Coupling Reactions of Glycine Derivatives

Peng Liu, Zhiming Wang, Jue Lin, Xianming Hu — 2012-01-30T:+05:00

[Full Paper]
Peng Liu, Zhiming Wang, Jue Lin, Xianming Hu
Eur. J. Org. Chem., January 30, 2012, DOI: 10.1002/ejoc.201101656. Read article.

Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids to Indolylnitroalkenes

Junwei Xing, Guihua Chen, Peng Cao, Jian Liao — 2012-01-04T:+05:00

[Full Paper]
Junwei Xing, Guihua Chen, Peng Cao, Jian Liao
Eur. J. Org. Chem., January 4, 2012, DOI: 10.1002/ejoc.201101648. Read article.

Preparation of New 1,4-Diazocanes as Scaffolds for Combinatorial Chemistry

Miriam Penning, Jens Christoffers — 2012-02-03T:+05:00

[Full Paper]
Miriam Penning, Jens Christoffers
Eur. J. Org. Chem., February 3, 2012, DOI: 10.1002/ejoc.201101645. Read article.

Controlling the Macroscopic Chirality of Organic Materials Based on 1,3,5-Trialkynylbenzenes
Dedicated to Dr. Helmut Sonnenschein on the occasion of his 60th birthday

2012-01-26T:+05:00

[Full Paper]
Gunther Hennrich, Belén Nieto-Ortega, Berta Gómez-Lor, Entique Gutierrez, Laura de Vega, Emma Cavero, Francisco J. Ramírez, Juan T. López Navarrete, Juan Casado
Eur. J. Org. Chem., January 26, 2012, DOI: 10.1002/ejoc.201101636. Read article.

Effects of Silyl Substituents on the Palladium-Catalyzed Asymmetric Synthesis of Axially Chiral (Allenylmethyl)silanes and Their S_E2' Chirality Transfer Reactions

Masamichi Ogasawara, Yonghui Ge, Atsushi Okada, Tamotsu Takahashi — 2012-01-30T:+05:00

[Full Paper]
Masamichi Ogasawara, Yonghui Ge, Atsushi Okada, Tamotsu Takahashi
Eur. J. Org. Chem., January 30, 2012, DOI: 10.1002/ejoc.201101634. Read article.

Selective Saccharide Recognition Using Modular Diboronic Acid Fluorescent Sensors

2012-01-05T:+05:00

[Full Paper]
Zhitao Xing, Hui-Chen Wang, Yixiang Cheng, Chengjian Zhu, Tony D. James, Jianzhang Zhao
Eur. J. Org. Chem., January 5, 2012, DOI: 10.1002/ejoc.201101633. Read article.

Promiscuous Behavior of Rhizomucor miehei Lipase in the Synthesis of N-Substituted β-Amino Esters

Leandro N. Monsalve, Florencia Gillanders, Alicia Baldessari — 2011-12-27T:+05:00

[Full Paper]
Leandro N. Monsalve, Florencia Gillanders, Alicia Baldessari
Eur. J. Org. Chem., December 27, 2011, DOI: 10.1002/ejoc.201101624. Read article.

A BODIPY-Based Highly Selective Fluorescent Chemosensor for Hg²⁺ Ions and Its Application in Living Cell Imaging

Mani Vedamalai, Shu-Pao Wu — 2012-01-04T:+05:00

[Full Paper]
Mani Vedamalai, Shu-Pao Wu
Eur. J. Org. Chem., January 4, 2012, DOI: 10.1002/ejoc.201101623. Read article.

Dendritic Architectures with Positively Charged Cores and Negatively Charged Shells

Torsten Schunk, Andreas Hirsch — 2011-12-21T:+05:00

[Full Paper]
Torsten Schunk, Andreas Hirsch
Eur. J. Org. Chem., December 21, 2011, DOI: 10.1002/ejoc.201101619. Read article.

1,2,4-Oxadiazole 4-Oxides as Nitrones in 1,3-Dipolar Cycloaddition Reactions to Vinyl Ethers

2012-01-20T:+05:00

[Full Paper]
Paolo Quadrelli, Fabio Lunghi, Bruna Bovio, William Gautschi, Pierluigi Caramella
Eur. J. Org. Chem., January 20, 2012, DOI: 10.1002/ejoc.201101615. Read article.

Synthetic Studies of Sesquiterpenes with the Dunniane Skeleton

2012-01-12T:+05:00

[Full Paper]
Sònia Parés, Ramon Alibés, Marta Figueredo, Josep Font, Teodor Parella
Eur. J. Org. Chem., January 12, 2012, DOI: 10.1002/ejoc.201101614. Read article.

Biosynthesis and Total Synthesis Studies on the Jadomycin Family of Natural Products

Ehesan U. Sharif, George A. O'Doherty — 2012-01-13T:+05:00

[Microreview]
Ehesan U. Sharif, George A. O'Doherty
Eur. J. Org. Chem., January 13, 2012, DOI: 10.1002/ejoc.201101609. Read article.

A Carbohydrate-Based Synthesis of the C13–C22 Fragment of Amphidinolide X

Mukund K. Gurjar, Gorakh S. Yellol, Debendra K. Mohapatra — 2012-02-06T:+05:00

[Full Paper]
Mukund K. Gurjar, Gorakh S. Yellol, Debendra K. Mohapatra
Eur. J. Org. Chem., February 6, 2012, DOI: 10.1002/ejoc.201101605. Read article.

The First Stereoselective Total Synthesis of Putaminoxin E and Its Epimer and Evaluation of Their Biological Properties
Synthetic Studies on Natural Products, 53; Part 52: D. B. Shinde, B. S. Kanth, M. Srilatha, B. Das, Synthesis 2011, in press.

2011-12-09T:+05:00

[Full Paper]
Chithaluri Sudhakar, Parigi Raghavendar Reddy, Chityal Ganesh Kumar, Pombala Sujitha, Biswanath Das
Eur. J. Org. Chem., December 9, 2011, DOI: 10.1002/ejoc.201101601. Read article.

Synthesis, Structure and Conformation of Terphenylene-Derived Oxacalixaromatics
Dedicated to Professor Wen-Qi Chen on the occasion of his 80th birthday

2012-01-17T:+05:00

[Full Paper]
Wen-Jing Hu, Xiao-Li Zhao, Ming-Liang Ma, Fang Guo, Xian-Qiang Mi, Biao Jiang, Ke Wen
Eur. J. Org. Chem., January 17, 2012, DOI: 10.1002/ejoc.201101599. Read article.

Regioselective Photochemical C–OMe Bond Formation Initiated by One-Electron Transfer and N–OMe Bond Fragmentation in Electron Donor–Acceptor Systems
Dedicated to the memory of Rafael Suau

Daniel Collado, Ezequiel Perez-Inestrosa — 2012-02-03T:+05:00

[Full Paper]
Daniel Collado, Ezequiel Perez-Inestrosa
Eur. J. Org. Chem., February 3, 2012, DOI: 10.1002/ejoc.201101595. Read article.

Complex-Induced Proximity Effect in the Regioselective Lithiation of Pyridine Derivatives

Jaspreet S. Dhau, Amritpal Singh, Yoganjaneyulu Kasetti, P. V. Bharatam — 2012-02-03T:+05:00

[Full Paper]
Jaspreet S. Dhau, Amritpal Singh, Yoganjaneyulu Kasetti, P. V. Bharatam
Eur. J. Org. Chem., February 3, 2012, DOI: 10.1002/ejoc.201101592. Read article.

Assignment of Absolute Configuration of Bis-γ-pyrone Polypropionates from Marine Pulmonate Molluscs

2012-01-18T:+05:00

[Short Communication]
Jian-Rong Wang, Marianna Carbone, Margherita Gavagnin, Attila Mándi, Sándor Antus, Li-Gong Yao, Guido Cimino, Tibor Kurtán, Yue-Wei Guo
Eur. J. Org. Chem., January 18, 2012, DOI: 10.1002/ejoc.201101587. Read article.

Design of New Tetrazine–Triphenylamine Bichromophores – Fluorescent Switching by Chemical Oxidation

2012-01-09T:+05:00

[Full Paper]
Cassandre Quinton, Valérie Alain-Rizzo, Cécile Dumas-Verdes, Gilles Clavier, Fabien Miomandre, Pierre Audebert
Eur. J. Org. Chem., January 9, 2012, DOI: 10.1002/ejoc.201101584. Read article.

Synthesis and Study of Oxadisilole-Fused Benzisoxazoles or Naphthisoxazoles

Xuyan Ma, Yali Chen, Yajuan Zhang, Di Xu, Weiguo Cao, Jie Chen — 2012-01-16T:+05:00

[Full Paper]
Xuyan Ma, Yali Chen, Yajuan Zhang, Di Xu, Weiguo Cao, Jie Chen
Eur. J. Org. Chem., January 16, 2012, DOI: 10.1002/ejoc.201101583. Read article.

Synthesis and Evaluation of Lipophilic BTBP Ligands for An/Ln Separation in Nuclear Waste Treatment: The Effect of Alkyl Substitution on Extraction Properties and Implications for Ligand Design

2012-01-12T:+05:00

[Full Paper]
Frank W. Lewis, Laurence M. Harwood, Michael J. Hudson, Petr Distler, Jan John, Karel Stamberg, Ana Núñez, Hitos Galán, Amparo G. Espartero
Eur. J. Org. Chem., January 12, 2012, DOI: 10.1002/ejoc.201101576. Read article.

Biosynthesis of Defensive Coccinellidae Alkaloids: Incorporation of Fatty Acids in Adaline, Coccinelline, and Harmonine

Eveline Haulotte, Pascal Laurent, and Jean-Claude Braekman — 2012-01-04T:+05:00

[Full Paper]
Eveline Haulotte, Pascal Laurent, and Jean-Claude Braekman
Eur. J. Org. Chem., January 4, 2012, DOI: 10.1002/ejoc.201101563. Read article.

An Ammonia-Triggered Stereocontrolled Conversion of a γ-Lactone to the Central Tetrahydropyran of Pederin, Psymberin, and Onnamides D–F
Dedicated to Professor Philip Kocienski, FRS

2012-01-11T:+05:00

[Full Paper]
William J. Buffham, Nigel A. Swain, Sarah L. Kostiuk, Théo P. Gonçalves, David C. Harrowven
Eur. J. Org. Chem., January 11, 2012, DOI: 10.1002/ejoc.201101543. Read article.

N¹-Functionalized Indole-Phosphane Oxazoline (IndPHOX) Ligands in Asymmetric Allylic Substitution Reactions

Yu Wang, Matti J. P. Vaismaa, Kari Rissanen, Robert Franzén — 2012-01-25T:+05:00

[Full Paper]
Yu Wang, Matti J. P. Vaismaa, Kari Rissanen, Robert Franzén
Eur. J. Org. Chem., January 25, 2012, DOI: 10.1002/ejoc.201101540. Read article.

Stereoselective Dihydroxylation Reaction of Alkenyl β-D-Hexopyranosides: A Methodology for the Synthesis of Glycosylglycerol Derivatives and 1-O-Acyl-3-O-β-D-glycosyl-sn-glycerol Analogues

2011-12-29T:+05:00

[Full Paper]
José M. Vega-Pérez, Carlos Palo-Nieto, Ignacio Periñán, Margarita Vega-Holm, José M. Calderón-Montaño, Miguel López-Lázaro, Fernando Iglesias-Guerra
Eur. J. Org. Chem., December 29, 2011, DOI: 10.1002/ejoc.201101539. Read article.

The New Age of Electrophilic Perfluoroalkylation Reactions
Dedicated to the memory of Professor Lev Yagupolskii

Yohan Macé, Emmanuel Magnier — 2012-01-11T:+05:00

[Microreview]
Yohan Macé, Emmanuel Magnier
Eur. J. Org. Chem., January 11, 2012, DOI: 10.1002/ejoc.201101535. Read article.

Highly Enantioselective Synthesis of Spiro[cyclohexanone-oxindoles] and Spiro[cyclohexanone-pyrazolones] by Asymmetric Cascade [5+1] Double Michael Reactions

2012-01-04T:+05:00

[Full Paper]
Bin Wu, Jian Chen, Mei-Qiu Li, Jin-Xin Zhang, Xiao-Ping Xu, Shun-Jun Ji, Xing-Wang Wang
Eur. J. Org. Chem., January 4, 2012, DOI: 10.1002/ejoc.201101529. Read article.

Recent Advances in the Total Synthesis of Chlorosulfolipids

Christian Nilewski, Erick M. Carreira — 2012-01-19T:+05:00

[Microreview]
Christian Nilewski, Erick M. Carreira
Eur. J. Org. Chem., January 19, 2012, DOI: 10.1002/ejoc.201101525. Read article.

Synthesis of Difluoromethyl-Containing α-Acyloxycarboxamide Derivatives through a Passerini Reaction and Desulfonylation

Jingjing Wu, Wenwen Zhao, Song Cao — 2012-01-23T:+05:00

[Full Paper]
Jingjing Wu, Wenwen Zhao, Song Cao
Eur. J. Org. Chem., January 23, 2012, DOI: 10.1002/ejoc.201101518. Read article.

Enantioselective Organocatalytic α-Alkylation of Ketones by S_N1-Type Reaction of Alcohols

Maria Trifonidou, Christoforos G. Kokotos — 2012-01-20T:+05:00

[Full Paper]
Maria Trifonidou, Christoforos G. Kokotos
Eur. J. Org. Chem., January 20, 2012, DOI: 10.1002/ejoc.201101509. Read article.

An Efficient Multigram Synthesis of Alkannin and Shikonin

2012-01-11T:+05:00

[Full Paper]
Rubing Wang, Shanshan Zhou, Hudagula Jiang, Xiaogang Zheng, Wen Zhou, Shaoshun Li
Eur. J. Org. Chem., January 11, 2012, DOI: 10.1002/ejoc.201101505. Read article.

Rapid Room-Temperature ¹¹C-Methylation of Arylamines with [¹¹C]Methyl Iodide Promoted by Solid Inorganic-Bases in DMF

Lisheng Cai, Rong Xu, Xuelei Guo, Victor W. Pike — 2012-01-09T:+05:00

[Full Paper]
Lisheng Cai, Rong Xu, Xuelei Guo, Victor W. Pike
Eur. J. Org. Chem., January 9, 2012, DOI: 10.1002/ejoc.201101499. Read article.

Trapping and Analysing Wheland–Meisenheimer σ Complexes, Usually Labile and Escaping Intermediates

Luciano Forlani, Carla Boga, Andrea Mazzanti, Nicola Zanna — 2011-12-23T:+05:00

[Full Paper]
Luciano Forlani, Carla Boga, Andrea Mazzanti, Nicola Zanna
Eur. J. Org. Chem., December 23, 2011, DOI: 10.1002/ejoc.201101498. Read article.

Glaser Coupling of 4-Ethynyl[2.2]paracyclophane: The Formation of Two Diastereomers
Cyclophanes, 68. Part 67: H. Hopf, H. Hinrichs, L. Ernst, P. G. Jones, V. Boekelheide, Isr. J. Chem., in press.

Henning Hopf, Ina Dix, Vitaly Raev, Ludger Ernst — 2012-01-26T:+05:00

[Full Paper]
Henning Hopf, Ina Dix, Vitaly Raev, Ludger Ernst
Eur. J. Org. Chem., January 26, 2012, DOI: 10.1002/ejoc.201101495. Read article.

Efficient Synthesis of Arylated Flavones by Site-Selective Suzuki–Miyaura Cross-Coupling Reactions of the Bis(triflate) of 5,7- and 7,8-Dihydroxyflavone

2012-01-30T:+05:00

[Full Paper]
Nadi Eleya, Imran Malik, Sebastian Reimann, Kai Wittler, Martin Hein, Tamás Patonay, Alexander Villinger, Ralf Ludwig, Peter Langer
Eur. J. Org. Chem., January 30, 2012, DOI: 10.1002/ejoc.201101491. Read article.

Nonenzymatic Acylative Kinetic Resolution of Racemic Amines and Related Compounds

Victor P. Krasnov, Dmitry A. Gruzdev, Galina L. Levit — 2011-12-16T:+05:00

[Microreview]
Victor P. Krasnov, Dmitry A. Gruzdev, Galina L. Levit
Eur. J. Org. Chem., December 16, 2011, DOI: 10.1002/ejoc.201101489. Read article.

Tetrakis(tetrathiafulvalene–tetrathiacrown ether)porphyrazine Triads: Synthesis, Photophysical, and Electrochemical Properties

Ruibin Hou, Bao Li, Keli Zhong, Hongda Li, Long-Yi Jin, Bingzhu Yin — 2012-01-09T:+05:00

[Full Paper]
Ruibin Hou, Bao Li, Keli Zhong, Hongda Li, Long-Yi Jin, Bingzhu Yin
Eur. J. Org. Chem., January 9, 2012, DOI: 10.1002/ejoc.201101484. Read article.

Polynuclear Copper(I) Complexes with Chelating Bis- and Tris-N-Heterocyclic Carbene Ligands: Catalytic Activity in Nitrene and Carbene Transfer Reactions

2012-01-18T:+05:00

[Full Paper]
Cristina Tubaro, Andrea Biffis, Riccardo Gava, Elena Scattolin, Andrea Volpe, Marino Basato, M. Mar Díaz-Requejo, Pedro J. Perez
Eur. J. Org. Chem., January 18, 2012, DOI: 10.1002/ejoc.201101480. Read article.

Towards the Total Synthesis of Mycaperoxide B: Probing Biosynthetic Rationale

Eduarda M. P. Silva, Richard J. Pye, Geoffrey D. Brown, Laurence M. Harwood — 2011-12-27T:+05:00

[Full Paper]
Eduarda M. P. Silva, Richard J. Pye, Geoffrey D. Brown, Laurence M. Harwood
Eur. J. Org. Chem., December 27, 2011, DOI: 10.1002/ejoc.201101477. Read article.

N-Acylpyrroles: More Than Amides

Anna M. Goldys, Christopher S. P. McErlean — 2011-12-20T:+05:00

[Microreview]
Anna M. Goldys, Christopher S. P. McErlean
Eur. J. Org. Chem., December 20, 2011, DOI: 10.1002/ejoc.201101470. Read article.

Sulfur–Nitrogen and Carbon–Nitrogen Bond Formation by Intermolecular Imination and Amidation without Catalyst

2012-01-26T:+05:00

[Full Paper]
Wen Bo Ma, Sheng Nan Li, Zhong Hua Zhou, Heng Shui Shen, Xue Li, Qiu Sun, Ling He, Ying Xue
Eur. J. Org. Chem., January 26, 2012, DOI: 10.1002/ejoc.201101463. Read article.

Studies on the Diastereoselective Intramolecular Pauson–Khand Reaction on Regioisomeric Chiral Perhydrobenzoxazines Derived from (–)-8-Aminomenthol

2011-12-27T:+05:00

[Full Paper]
Alicia Maestro, Rafael Pedrosa, Alfonso Pérez-Encabo, Juan J. Pérez-Rueda
Eur. J. Org. Chem., December 27, 2011, DOI: 10.1002/ejoc.201101462. Read article.

Copper-Catalyzed Cascade Reaction of 4-Iodopyrazole Derivatives with Amidines for the Synthesis of Pyrazolo[4,3-d]pyrimidine Derivatives
CDRI Communication Number 8161

Maloy Nayak, Neeraj Rastogi, Sanjay Batra — 2012-01-10T:+05:00

[Full Paper]
Maloy Nayak, Neeraj Rastogi, Sanjay Batra
Eur. J. Org. Chem., January 10, 2012, DOI: 10.1002/ejoc.201101454. Read article.

Synthesis, Spectroscopic and Thermal Characterization of Azido-1,2,4-triazoles: A Class of Heteroarenes with a High Nitrogen Content

2011-12-29T:+05:00

[Full Paper]
Paolo Cardillo, Marco Dellavedova, Lucia Gigante, Angelo Lunghi, Christian Pasturenzi, Elisabetta Salatelli, Paolo Zanirato
Eur. J. Org. Chem., December 29, 2011, DOI: 10.1002/ejoc.201101450. Read article.

A Synthetic Overview of Radiolabeled Compounds for β-Amyloid Targeting

Goreti Ribeiro Morais, António Paulo, Isabel Santos — 2011-12-28T:+05:00

[Microreview]
Goreti Ribeiro Morais, António Paulo, Isabel Santos
Eur. J. Org. Chem., December 28, 2011, DOI: 10.1002/ejoc.201101449. Read article.

New Anthracene Derivatives – Structure Elucidation and Antimicrobial Activity

2012-01-10T:+05:00

[Full Paper]
Abdessamad Debbab, Amal H. Aly, Ruangelie Edrada-Ebel, Victor Wray, Alexander Pretsch, Gennaro Pescitelli, Tibor Kurtan, Peter Proksch
Eur. J. Org. Chem., January 10, 2012, DOI: 10.1002/ejoc.201101442. Read article.

Site-Directed Spin Labelling of Nucleic Acids

Sandip A. Shelke, Snorri Th. Sigurdsson — 2012-01-13T:+05:00

[Microreview]
Sandip A. Shelke, Snorri Th. Sigurdsson
Eur. J. Org. Chem., January 13, 2012, DOI: 10.1002/ejoc.201101434. Read article.

Segment Solid-Phase Total Synthesis of the Anthelmintic Cyclooctadepsipeptides PF1022A and Emodepside

2012-01-24T:+05:00

[Full Paper]
Jürgen Scherkenbeck, Sebastian Lüttenberg, Monika Ludwig, Karin Brücher, Andreas Kotthaus
Eur. J. Org. Chem., January 24, 2012, DOI: 10.1002/ejoc.201101421. Read article.

Concave Annelated Terpyridines
Concave Reagents, 61; Part 60: D. Stoltenberg, S. Lüthje, O. Winkelmann, C. Näther, U. Lüning, Eur. J. Org. Chem. 2011, 5845–5859.

Ulrich Lüning, Timo Liebig — 2012-01-11T:+05:00

[Full Paper]
Ulrich Lüning, Timo Liebig
Eur. J. Org. Chem., January 11, 2012, DOI: 10.1002/ejoc.201101356. Read article.

Silicone-Supported Cinchona Alkaloid Derivatives as Insoluble Organocatalysts in the Enantioselective Dimerization of Ketenes

Damiano Cancogni, Alessandro Mandoli, Ravindra P. Jumde, Dario Pini — 2012-01-25T:+05:00

[Full Paper]
Damiano Cancogni, Alessandro Mandoli, Ravindra P. Jumde, Dario Pini
Eur. J. Org. Chem., January 25, 2012, DOI: 10.1002/ejoc.201101320. Read article.

Facial Selectivity in the Diels–Alder Reactions of 2,2-Disubstituted Cyclopent-4-ene-1,3-dione Derivatives and a Computational Examination of the Facial Selectivity of the Diels–Alder Reactions of Structurally Related Dienes and Dienophiles

2011-12-28T:+05:00

[Full Paper]
Pei-Ying Liu, Yong-Jin Wu, Cory C. Pye, Paul D. Thornton, Raymond A. Poirier, D. Jean Burnell
Eur. J. Org. Chem., December 28, 2011, DOI: 10.1002/ejoc.201101301. Read article.

P–C Cross-Coupling Onto Enamides: Versatile Synthesis of α-Enamido Phosphane Derivatives

2012-01-13T:+05:00

[Short Communication]
Monika Cieslikiewicz, Alexis Bouet, Sylvain Jugé, Martial Toffano, Jérôme Bayardon, Caroline West, Krzystof Lewinski, Isabelle Gillaizeau
Eur. J. Org. Chem., January 13, 2012, DOI: 10.1002/ejoc.201101293. Read article.

Protecting Group Free Formal Total Synthesis of the Antitubercular Agent Erogorgiaene

Jhillu S. Yadav, Bodakuntla Thirupathaiah,, Ahmad Al Khazim Al Ghamdi — 2011-11-03T:+05:00

[Full Paper]
Jhillu S. Yadav, Bodakuntla Thirupathaiah,, Ahmad Al Khazim Al Ghamdi
Eur. J. Org. Chem., November 3, 2011, DOI: 10.1002/ejoc.201101269. Read article.

Cu-Catalyzed Enantioselective 1,4-Additions of Aryl-Grignard Reagents to Cyclohexenone in the Presence of TADDOL-Derived Phosphane-Phosphite Ligands
Dedicated to Professor Mohammed A. Omary

2011-12-23T:+05:00

[Full Paper]
Qaseem Naeemi, Mehmet Dindaroğlu, Darius P. Kranz, Janna Velder, Hans-Günther Schmalz
Eur. J. Org. Chem., December 23, 2011, DOI: 10.1002/ejoc.201101258. Read article.

Anthracene-Labeled 1,2,3-Triazole-Linked Bispyridinium Amide for Selective Sensing of H₂PO₄^– by Fluorescence and Gel Formation

Kumaresh Ghosh, Avik Ranjan Sarkar, Asoke P. Chattopadhyay — 2012-01-16T:+05:00

[Full Paper]
Kumaresh Ghosh, Avik Ranjan Sarkar, Asoke P. Chattopadhyay
Eur. J. Org. Chem., January 16, 2012, DOI: 10.1002/ejoc.201101240. Read article.

Phenanthroline- and Terpyridine-Substituted Tetralactam Macrocycles: A Facile Route to Rigid Di- and Trivalent Receptors and Interlocked Molecules

Egor V. Dzyuba, Bilge Baytekin, Dominik Sattler, Christoph A. Schalley — 2011-12-28T:+05:00

[Full Paper]
Egor V. Dzyuba, Bilge Baytekin, Dominik Sattler, Christoph A. Schalley
Eur. J. Org. Chem., December 28, 2011, DOI: 10.1002/ejoc.201101231. Read article.

New Directions in Ketene Chemistry: The Land of Opportunity

Annette D. Allen, Thomas T. Tidwell — 2011-11-11T:+05:00

[Microreview]
Annette D. Allen, Thomas T. Tidwell
Eur. J. Org. Chem., November 11, 2011, DOI: 10.1002/ejoc.201101230. Read article.

Regioselective Photochemical Rearrangement of N-Mesyloxylactams

Simon Pichette, Samuel Aubert-Nicol, Jean Lessard, Claude Spino — 2012-01-09T:+05:00

[Full Paper]
Simon Pichette, Samuel Aubert-Nicol, Jean Lessard, Claude Spino
Eur. J. Org. Chem., January 9, 2012, DOI: 10.1002/ejoc.201101222. Read article.

Synthesis of the Indolic Pentacyclic Core of Manadomanzamine A Following Biogenetically Based Strategies
Dedicated to the memory of François Tillequin

2012-01-04T:+05:00

[Full Paper]
Lok-Hang Yan, Philippe Nuhant, Isabelle Sinigaglia, Yann Fromentin, Christian Marazano, Bernard Delpech, Erwan Poupon
Eur. J. Org. Chem., January 4, 2012, DOI: 10.1002/ejoc.201101133. Read article.

Activation of Gas-Phase Uranyl Diacetone Alcohol Coordination Complexes by Spectator Ligand Addition

Daniel Rios, John K. Gibson — 2012-02-03T:+05:00

[Full Paper]
Daniel Rios, John K. Gibson
Eur. J. Inorg. Chem., February 3, 2012, DOI: 10.1002/ejic.201200024. Read article.

Bidentate and Tetradentate β-Aminovinyl Trifluoromethylated Ketones and Their Copper(II) Complexes: Synthesis, Characterization and Redox Chemistry

Nicolas Chopin, Maurice Médebielle, Guillaume Pilet — 2012-01-27T:+05:00

[Full Paper]
Nicolas Chopin, Maurice Médebielle, Guillaume Pilet
Eur. J. Inorg. Chem., January 27, 2012, DOI: 10.1002/ejic.201101385. Read article.

Structure–Relaxivity Relationships among Targeted MR Contrast Agents

Peter Caravan, Zhaoda Zhang — 2012-02-03T:+05:00

[Microreview]
Peter Caravan, Zhaoda Zhang
Eur. J. Inorg. Chem., February 3, 2012, DOI: 10.1002/ejic.201101364. Read article.

Diene Dissolution of the Heavier Alkaline Earth Metals

2012-01-13T:+05:00

[Full Paper]
Olaf Michel, Hiroshi Kaneko, Hayato Tsurugi, Koji Yamamoto, Karl W. Törnroos, Reiner Anwander, Kazushi Mashima
Eur. J. Inorg. Chem., January 13, 2012, DOI: 10.1002/ejic.201101342. Read article.

Synthesis, Reactivity and Ring-Opening Polymerization of a Tin-Bridged ansa-Cycloheptatrienyl-Cyclopentadienyl Titanium Sandwich Complex

Alain C. Tagne Kuate, Constantin G. Daniliuc, Peter G. Jones, Matthias Tamm — 2012-01-27T:+05:00

[Full Paper]
Alain C. Tagne Kuate, Constantin G. Daniliuc, Peter G. Jones, Matthias Tamm
Eur. J. Inorg. Chem., January 27, 2012, DOI: 10.1002/ejic.201101339. Read article.

Room-Temperature Sol–Gel Synthesis of Sodium Hexaniobate in an Immiscible Hexane–Water System and Its Conversion into NaNbO₃

Masahiro Tanaka, Shinobu Fujihara — 2012-02-06T:+05:00

[Full Paper]
Masahiro Tanaka, Shinobu Fujihara
Eur. J. Inorg. Chem., February 6, 2012, DOI: 10.1002/ejic.201101329. Read article.

Isolation of a New C_s-Symmetrized Mo₃(μ₃-S)(μ-S)(μ-S₂)₂ Structural Type Through Complementary Association with a Cubane-Type Mo₃NiS₄ Cluster

Rita Hernandez-Molina, Javier Gonzalez-Platas, Cristian Vicent — 2012-02-06T:+05:00

[Full Paper]
Rita Hernandez-Molina, Javier Gonzalez-Platas, Cristian Vicent
Eur. J. Inorg. Chem., February 6, 2012, DOI: 10.1002/ejic.201101326. Read article.

Structure–Photoluminescence Quenching Relationships of Iridium(III)–Tris(phenylpyridine) Complexes

2012-01-11T:+05:00

[Full Paper]
Albert Ruggi, Matteo Mauro, Federico Polo, David N. Reinhoudt, Luisa De Cola, Aldrik H. Velders
Eur. J. Inorg. Chem., January 11, 2012, DOI: 10.1002/ejic.201101315. Read article.

Gd-Aminoethyl-DO3A Complexes: A Novel Class of pH-Sensitive MRI Contrast Agents

Giovanni B. Giovenzana, Roberto Negri, Gabriele A. Rolla, Lorenzo Tei — 2012-01-23T:+05:00

[Short Communication]
Giovanni B. Giovenzana, Roberto Negri, Gabriele A. Rolla, Lorenzo Tei
Eur. J. Inorg. Chem., January 23, 2012, DOI: 10.1002/ejic.201101296. Read article.

Influence of gem-Dimethyl Substitution on the Stability, Kinetics and Relaxometric Properties of PDTA Complexes

2012-02-07T:+05:00

[Full Paper]
Attila Forgács, Giovanni B. Giovenzana, Mauro Botta, Ernő Brücher, Imre Tóth, Zsolt Baranyai
Eur. J. Inorg. Chem., February 7, 2012, DOI: 10.1002/ejic.201101294. Read article.

Single-Strand Molecular Wheels and Coordination Polymers in Copper(II) Benzoate Chemistry by the Employment of α-Benzoin Oxime and Azides: Synthesis, Structures, and Magnetic Characterization

2012-01-10T:+05:00

[Full Paper]
Theocharis C. Stamatatos, Gina Vlahopoulou, Catherine P. Raptopoulou, Vassilis Psycharis, Albert Escuer, George Christou, Spyros P. Perlepes
Eur. J. Inorg. Chem., January 10, 2012, DOI: 10.1002/ejic.201101292. Read article.

Chemical Exchange Saturation Transfer Is Unaffected by Modest Changes in Pressure

Benjamin C. Webber, Christiane E. Carney, Mark Woods — 2012-01-09T:+05:00

[Short Communication]
Benjamin C. Webber, Christiane E. Carney, Mark Woods
Eur. J. Inorg. Chem., January 9, 2012, DOI: 10.1002/ejic.201101291. Read article.

Ca₂NiSn₂ – A Polymorphic Intermetallic Phase: Atomic and Electronic Structure as well as a Topological Description of the Phase Transition by a Sigmatropic-Type Rearrangement of Ni and Sn Atoms

Lisa Siggelkow, Viktor Hlukhyy, Thomas F. Fässler — 2012-01-12T:+05:00

[Full Paper]
Lisa Siggelkow, Viktor Hlukhyy, Thomas F. Fässler
Eur. J. Inorg. Chem., January 12, 2012, DOI: 10.1002/ejic.201101277. Read article.

Molecular Structure of a Hydridoniobocene Complex [Nb(η⁵-C₅H₄SiMe₃)₂(H)₃] and Its Use as Catalyst for the Ring-Opening Polymerization of Cyclic Esters

2012-02-03T:+05:00

[Full Paper]
Carlos Alonso-Moreno, Antonio Antiñolo, Joaquín C. García-Martínez, Santiago García-Yuste, Isabel López-Solera, Antonio Otero, Juan C. Pérez-Flores, Maria T. Tercero-Morales
Eur. J. Inorg. Chem., February 3, 2012, DOI: 10.1002/ejic.201101263. Read article.

Amide and Urea Ferrocene-Containing Macrocycles Capable of the Electrochemical Sensing of Anions

Nicholas H. Evans, Christopher J. Serpell, Kirsten E. Christensen, Paul D. Beer — 2012-01-17T:+05:00

[Full Paper]
Nicholas H. Evans, Christopher J. Serpell, Kirsten E. Christensen, Paul D. Beer
Eur. J. Inorg. Chem., January 17, 2012, DOI: 10.1002/ejic.201101257. Read article.

Silver Melonates and Coordination Modes of the Multidentate [C₆N₇(NCN)₃]^3– Anion

Corinna Clauss, Uwe Böhme, Anke Schwarzer, Edwin Kroke — 2012-01-13T:+05:00

[Full Paper]
Corinna Clauss, Uwe Böhme, Anke Schwarzer, Edwin Kroke
Eur. J. Inorg. Chem., January 13, 2012, DOI: 10.1002/ejic.201101254. Read article.

Application of Nickel Complexes Modified by Tridentate O,N,O'-Ligands as Precatalysts in Nickel-Catalyzed C(sp²)–C(sp³) Bond Formations

2012-02-07T:+05:00

[Full Paper]
Chika I. Someya, Shigeyoshi Inoue, Sebastian Krackl, Elisabeth Irran, Stephan Enthaler
Eur. J. Inorg. Chem., February 7, 2012, DOI: 10.1002/ejic.201101253. Read article.

Coordinating Properties of Pyrone and Pyridinone Derivatives, Tropolone and Catechol toward the VO²⁺ Ion: An Experimental and Computational Approach

2012-02-03T:+05:00

[Full Paper]
Daniele Sanna, Péter Buglyó, Linda Bíró, Giovanni Micera, Eugenio Garribba
Eur. J. Inorg. Chem., February 3, 2012, DOI: 10.1002/ejic.201101249. Read article.

2D Magnetic Frames Obtained by the Microwave-Assisted Chemistry Approach

Oana Pascu, Martí Gich, Gervasi Herranz, Anna Roig — 2012-01-09T:+05:00

[Short Communication]
Oana Pascu, Martí Gich, Gervasi Herranz, Anna Roig
Eur. J. Inorg. Chem., January 9, 2012, DOI: 10.1002/ejic.201101244. Read article.

Derivatives of Photosensitive CORM-S1 – CO Complexes of Iron and Ruthenium with the (OC)₂M(S–C–C–NH₂)₂ Fragment

2012-01-31T:+05:00

[Full Paper]
Vaneza P. Lorett Velásquez, Taghreed M. A. Jazzazi, Astrid Malassa, Helmar Görls, Guido Gessner, Stefan H. Heinemann, Matthias Westerhausen
Eur. J. Inorg. Chem., January 31, 2012, DOI: 10.1002/ejic.201101230. Read article.

Fe^III Spin-Crossover Complexes with Photoisomerizable Ligands: Experimental and Theoretical Studies on the Ligand-Driven Light-Induced Spin Change Effect

2012-01-27T:+05:00

[Full Paper]
Alexander Bannwarth, Sven Olaf Schmidt, Gerhard Peters, Frank D. Sönnichsen, Wulf Thimm, Rainer Herges, Felix Tuczek
Eur. J. Inorg. Chem., January 27, 2012, DOI: 10.1002/ejic.201101227. Read article.

Synthesis of Oligomeric Zinc Complexes with Bicyclic and Acyclic Guanidinate Ligands
Dedicated to Prof. Dr. mult. Alois Haas on the occasion of his 80th birthday

2012-02-03T:+05:00

[Full Paper]
Christiane Neuhäuser, Matthias Reinmuth, Elisabeth Kaifer, Hans-Jörg Himmel
Eur. J. Inorg. Chem., February 3, 2012, DOI: 10.1002/ejic.201101223. Read article.

Functional Heterometallic Layered Hybrid Magnets by Double Ion-Exchange

2012-01-12T:+05:00

[Full Paper]
Emilie Delahaye, Séraphin Eyele-Mezui, Mayoro Diop, Cédric Leuvrey, Dominique Foix, Danielle Gonbeau, Pierre Rabu, Guillaume Rogez
Eur. J. Inorg. Chem., January 12, 2012, DOI: 10.1002/ejic.201101220. Read article.

A Cyano-Bridged Vanadium–Niobium Bimetal Assembly Exhibiting a High Curie Temperature of 210 K

Kenta Imoto, Miho Takemura, Hiroko Tokoro, Shin-ichi Ohkoshi — 2011-12-19T:+05:00

[Short Communication]
Kenta Imoto, Miho Takemura, Hiroko Tokoro, Shin-ichi Ohkoshi
Eur. J. Inorg. Chem., December 19, 2011, DOI: 10.1002/ejic.201101219. Read article.

Di-, Tetra-, Penta- and Polynuclear Zinc Complexes Supported by a Flexible Tetradentate Schiff Base Ligand

David J. D. Wilson, Christine M. Beavers, Anne F. Richards — 2012-01-24T:+05:00

[Full Paper]
David J. D. Wilson, Christine M. Beavers, Anne F. Richards
Eur. J. Inorg. Chem., January 24, 2012, DOI: 10.1002/ejic.201101202. Read article.

Expected and Unconventional Ag⁺ Binding Modes in Heteronuclear Pt,Ag Coordination Polymers Derived from trans-[Pt(methylamine)₂(pyrazole)₂]²⁺

Pilar Brandi-Blanco, Pablo J. Sanz Miguel, Bernhard Lippert — 2012-01-30T:+05:00

[Full Paper]
Pilar Brandi-Blanco, Pablo J. Sanz Miguel, Bernhard Lippert
Eur. J. Inorg. Chem., January 30, 2012, DOI: 10.1002/ejic.201101197. Read article.

Ferrocenyl Maleimides – Synthesis, (Spectro-)Electrochemistry, and Solvatochromism

2012-01-31T:+05:00

[Full Paper]
Alexander Hildebrandt, Steve W. Lehrich, Dieter Schaarschmidt, Romy Jaeschke, Katja Schreiter, Stefan Spange, Heinrich Lang
Eur. J. Inorg. Chem., January 31, 2012, DOI: 10.1002/ejic.201101191. Read article.

[V₁₅Ge₆O₄₂S₆(H₂O)]^12–, a Thiogermanatopolyoxovanadate Cluster Featuring the Spin Topology of the Molecular Magnet [V₁₅As₆O₄₂(H₂O)]^6–

Jing Wang, Christian Näther, Paul Kögerler, Wolfgang Bensch — 2012-02-03T:+05:00

[Full Paper]
Jing Wang, Christian Näther, Paul Kögerler, Wolfgang Bensch
Eur. J. Inorg. Chem., February 3, 2012, DOI: 10.1002/ejic.201101187. Read article.

A Facile Approach for Transferring PbS Colloidal Photonic Structures into Alkanol Solutions and Composite Solid Films

Chunguang Li, Tianyu Bai, Tao Li, Feifei Li, Wenjun Dong, Zhan Shi, Shouhua Feng — 2012-02-03T:+05:00

[Full Paper]
Chunguang Li, Tianyu Bai, Tao Li, Feifei Li, Wenjun Dong, Zhan Shi, Shouhua Feng
Eur. J. Inorg. Chem., February 3, 2012, DOI: 10.1002/ejic.201101183. Read article.

Structural Conformation and Optical and Electrochemical Properties of Imidazolyl-Substituted Naphthalenediimide and Its Hg^II, Cd^II, and Cu^II Halide Complexes

2012-01-26T:+05:00

[Full Paper]
Jia-Jian Jiang, Cheng Yan, Mei Pan, Zi Wang, Hai-Ying Deng, Jian-Rong He, Qing-Yuan Yang, Lei Fu, Xian-Fang Xu, Cheng-Yong Su
Eur. J. Inorg. Chem., January 26, 2012, DOI: 10.1002/ejic.201101181. Read article.

The Nature of Spin Crossover and Coordination Core Distortion in a Family of Binuclear Iron(II) Complexes with Bipyridyl-Like Bridging Ligands

Galina S. Matouzenko, Erwann Jeanneau, Alexander Yu. Verat, Yannick de Gaetano — 2012-01-23T:+05:00

[Full Paper]
Galina S. Matouzenko, Erwann Jeanneau, Alexander Yu. Verat, Yannick de Gaetano
Eur. J. Inorg. Chem., January 23, 2012, DOI: 10.1002/ejic.201101178. Read article.

The Development of Iron(II) Complexes as ParaCEST MRI Contrast Agents

Sarina J. Dorazio, Janet R. Morrow — 2012-01-13T:+05:00

[Microreview]
Sarina J. Dorazio, Janet R. Morrow
Eur. J. Inorg. Chem., January 13, 2012, DOI: 10.1002/ejic.201101169. Read article.

Conjugation to Biocompatible Dendrimers Increases Lanthanide T₂ Relaxivity of Hydroxypyridinone Complexes for Magnetic Resonance Imaging

2012-02-06T:+05:00

[Full Paper]
Piper J. Klemm, William C. Floyd III, Christopher M. Andolina, Jean M. J. Fréchet, Kenneth N. Raymond
Eur. J. Inorg. Chem., February 6, 2012, DOI: 10.1002/ejic.201101167. Read article.

The Solution Structure and Dynamics of MRI Probes Based on Lanthanide(III) DOTA as Investigated by DFT and NMR Spectroscopy

Carlos Platas-Iglesias — 2011-12-21T:+05:00

[Microreview]
Carlos Platas-Iglesias
Eur. J. Inorg. Chem., December 21, 2011, DOI: 10.1002/ejic.201101164. Read article.

New Bisaqua Picolinate-Based Gadolinium Complexes as MRI Contrast Agents with Substantial High-Field Relaxivities

2012-01-13T:+05:00

[Full Paper]
Aline M. Nonat, Christelle Gateau, Pascal H. Fries, Lothar Helm, Marinella Mazzanti
Eur. J. Inorg. Chem., January 13, 2012, DOI: 10.1002/ejic.201101162. Read article.

PTA-Stabilized Ruthenium and Platinum Nanoparticles: Characterization and Investigation in Aqueous Biphasic Hydrogenation Catalysis

2012-02-06T:+05:00

[Full Paper]
Pierre-Jean Debouttière, Yannick Coppel, Audrey Denicourt-Nowicki, Alain Roucoux, Bruno Chaudret, Karine Philippot
Eur. J. Inorg. Chem., February 6, 2012, DOI: 10.1002/ejic.201101159. Read article.

Catalytic Hydrocarbon Functionalization with Gold Complexes Containing N-Heterocyclic Carbene Ligands with Pendant Donor Groups

2012-01-09T:+05:00

[Full Paper]
Manuela Delgado-Rebollo, Alvaro Beltrán, Auxiliadora Prieto, M. Mar Díaz-Requejo, Antonio M. Echavarren, Pedro J. Pérez
Eur. J. Inorg. Chem., January 9, 2012, DOI: 10.1002/ejic.201101158. Read article.

Hexaphosphine: A Multifaceted Ligand for Transition Metal Coordination
Dedicated to Professor Philippe Meunier on the occasion of his 65th birthday

2011-12-15T:+05:00

[Short Communication]
Radomyr V. Smaliy, Matthieu Beaupérin, Arnaud Mielle, Philippe Richard, Hélène Cattey, Aleksandr N. Kostyuk, Jean-Cyrille Hierso
Eur. J. Inorg. Chem., December 15, 2011, DOI: 10.1002/ejic.201101142. Read article.

Blood-Pool and Targeting MRI Contrast Agents: From Gd-Chelates to Gd-Nanoparticles

Gang Ho Lee, Yongmin Chang, Tae-Jeong Kim — 2012-01-04T:+05:00

[Microreview]
Gang Ho Lee, Yongmin Chang, Tae-Jeong Kim
Eur. J. Inorg. Chem., January 4, 2012, DOI: 10.1002/ejic.201101137. Read article.

Synthesis and Characterization of Surface-Functionalized Layered Titanate Nanosheets Using Lamellar Self-Assembly as a Template

2012-02-06T:+05:00

[Full Paper]
Keizo Nakagawa, Kazuki Yamaguchi, Keiji Yamada, Ken-Ichiro Sotowa, Shigeru Sugiyama, Motonari Adachi
Eur. J. Inorg. Chem., February 6, 2012, DOI: 10.1002/ejic.201101136. Read article.

Pompon-Like MnF₂ Nanostructures from a Single-Source Precursor through Atmospheric Pressure Chemical Vapor Deposition

2012-02-06T:+05:00

[Short Communication]
Graziella Malandrino, Roberta G. Toro, Maria R. Catalano, Maria E. Fragalà, Patrizia Rossi, Paola Paoli
Eur. J. Inorg. Chem., February 6, 2012, DOI: 10.1002/ejic.201101121. Read article.

Synthesis and Structure of Silver Amino-Arenesulfonates

Madleen Busse, Philip C. Andrews, Peter C. Junk — 2012-01-31T:+05:00

[Full Paper]
Madleen Busse, Philip C. Andrews, Peter C. Junk
Eur. J. Inorg. Chem., January 31, 2012, DOI: 10.1002/ejic.201101119. Read article.

Silica Nanoparticles for Bimodal MRI–Optical Imaging by Grafting Gd³⁺ and Eu³⁺/Tb³⁺ Complexes

2012-01-19T:+05:00

[Full Paper]
Sonia L. C. Pinho, Henrique Faneca, Carlos F. G. C. Geraldes, João Rocha, Luís D. Carlos, Marie-Hélène Delville
Eur. J. Inorg. Chem., January 19, 2012, DOI: 10.1002/ejic.201101110. Read article.

Syntheses and Structural Study of Novel Tetranuclear Bis(phenoxido)-Bridged Cu^II Metal–Organic Macrocycles

Antti Riisiö, Mikko M. Hänninen, Reijo Sillanpää — 2012-01-27T:+05:00

[Full Paper]
Antti Riisiö, Mikko M. Hänninen, Reijo Sillanpää
Eur. J. Inorg. Chem., January 27, 2012, DOI: 10.1002/ejic.201101103. Read article.

Synthesis, Structural Characterization, and Catalytic Performance of a Vanadium-Based Metal–Organic Framework (COMOC-3)

2011-12-16T:+05:00

[Full Paper]
Ying-Ya Liu, Karen Leus, Maciej Grzywa, David Weinberger, Katrien Strubbe, Henk Vrielinck, Rik Van Deun, Dirk Volkmer, Veronique Van Speybroeck, Pascal Van Der Voort
Eur. J. Inorg. Chem., December 16, 2011, DOI: 10.1002/ejic.201101099. Read article.

New Octahedral, Head–Tail Iron(II) Complexes with Spin Crossover Properties

Stephan Schlamp, Peter Thoma, Birgit Weber — 2011-12-08T:+05:00

[Full Paper]
Stephan Schlamp, Peter Thoma, Birgit Weber
Eur. J. Inorg. Chem., December 8, 2011, DOI: 10.1002/ejic.201101096. Read article.

Peculiarities of Vibrational Spectra and Electronic Structure of the Five-Membered Metallacyclocumulenes of the Group 4 Metals

2012-01-25T:+05:00

[Full Paper]
Rinat R. Aysin, Larissa A. Leites, Vladimir V. Burlakov, Vladimir B. Shur, Torsten Beweries, Uwe Rosenthal
Eur. J. Inorg. Chem., January 25, 2012, DOI: 10.1002/ejic.201101088. Read article.

K_β Detected High-Resolution XANES of Fe^II and Fe^III Models of the 2-His-1-Carboxylate Motif: Analysis of the Carboxylate Binding Mode

2012-01-30T:+05:00

[Full Paper]
Ana Mijovilovich, Hisashi Hayashi, Naomi Kawamura, Hitoshi Osawa, Pieter C. A. Bruijnincx, Robertus J. M. Klein Gebbink, Frank M. F. de Groot, Bert M. Weckhuysen
Eur. J. Inorg. Chem., January 30, 2012, DOI: 10.1002/ejic.201101075. Read article.

Rhodium (Thiophosphinoyl)(trimethylsilyl)methanide and Bis(thiophosphinoyl)methanide Complexes: S~S vs. C~S Coordination
Dedicated to the memory of our friend and colleague Pascal Le Floch

2012-01-27T:+05:00

[Full Paper]
Hadrien Heuclin, Sophie Carenco, Xavier-Frédéric Le Goff, Nicolas Mézailles
Eur. J. Inorg. Chem., January 27, 2012, DOI: 10.1002/ejic.201101073. Read article.

Crystal-Phase- and Morphology-Controlled Synthesis of Fe₂O₃ Nanomaterials

2012-01-26T:+05:00

[Full Paper]
Xiaoling Mou, Yong Li, Bingsen Zhang, Lide Yao, Xuejiao Wei, Dang Sheng Su, Wenjie Shen
Eur. J. Inorg. Chem., January 26, 2012, DOI: 10.1002/ejic.201101066. Read article.

Synthesis of Mesoporous Zirconium Organophosphonate Solid-Acid Catalysts

Xiu-Zhen Lin, Zhong-Yong Yuan — 2011-12-06T:+05:00

[Short Communication]
Xiu-Zhen Lin, Zhong-Yong Yuan
Eur. J. Inorg. Chem., December 6, 2011, DOI: 10.1002/ejic.201101064. Read article.

One-Dimensional 3d–3d–4f Trimetallic Assemblies Consisting of Cu^II₂Ln^III Trinuclear Complexes and Hexacyanometallate

2012-02-03T:+05:00

[Full Paper]
Takuya Shiga, Akio Mishima, Kunihisa Sugimoto, Hisashi Okawa, Hiroki Oshio, Masaaki Ohba
Eur. J. Inorg. Chem., February 3, 2012, DOI: 10.1002/ejic.201101060. Read article.

Synthesis and Characterization of Gold Nanostars as Filler of Tunneling Conductive Polymer Composites

2012-01-31T:+05:00

[Short Communication]
Stefano Stassi, Valentina Cauda, Giancarlo Canavese, Diego Manfredi, Candido Fabrizio Pirri
Eur. J. Inorg. Chem., January 31, 2012, DOI: 10.1002/ejic.201101058. Read article.

Thiolato-Bridged Arene–Ruthenium Complexes: Synthesis, Molecular Structure, Reactivity, and Anticancer Activity of the Dinuclear Complexes [(arene)₂Ru₂(SR)₂Cl₂]
Dedicated to Dr. Hubert Le Bozec on the occasion of his 60th birthday

2011-12-16T:+05:00

[Full Paper]
Anne-Flore Ibao, Michaël Gras, Bruno Therrien, Georg Süss-Fink, Olivier Zava, Paul J. Dyson
Eur. J. Inorg. Chem., December 16, 2011, DOI: 10.1002/ejic.201101057. Read article.

MOFs for Use in Adsorption Heat Pump Processes

Stefan K. Henninger, Felix Jeremias, Harry Kummer, Christoph Janiak — 2011-12-13T:+05:00

[Microreview]
Stefan K. Henninger, Felix Jeremias, Harry Kummer, Christoph Janiak
Eur. J. Inorg. Chem., December 13, 2011, DOI: 10.1002/ejic.201101056. Read article.

Synthesis and Characterization of New Pentacoordinate Iron-Based Aryloxide Complexes

Yvens Chérémond, Aurélien Crochet, Katharina M. Fromm — 2012-01-24T:+05:00

[Full Paper]
Yvens Chérémond, Aurélien Crochet, Katharina M. Fromm
Eur. J. Inorg. Chem., January 24, 2012, DOI: 10.1002/ejic.201101054. Read article.

The Question of cis versus trans Configuration in Octahedral Metal Diketonates: An In-Depth Investigation on Diorganobis(4-acyl-5-pyrazolonato)tin(IV) Complexes

2012-01-17T:+05:00

[Full Paper]
Francesco Caruso, Eric J. Chan, John V. Hanna, Fabio Marchetti, Claudio Pettinari, Corrado Di Nicola, Riccardo Pettinari, Adriano Pizzabiocca, Gregory J. Rees, David Quigley, Miriam Rossi, Brian W. Skelton, Alexandre N. Sobolev, Allan H. White
Eur. J. Inorg. Chem., January 17, 2012, DOI: 10.1002/ejic.201101050. Read article.

Synthesis of Stable Ruthenium Olefin Metathesis Catalysts with Mixed Anionic Ligands

Rafał Gawin, Karol Grela — 2012-01-31T:+05:00

[Full Paper]
Rafał Gawin, Karol Grela
Eur. J. Inorg. Chem., January 31, 2012, DOI: 10.1002/ejic.201101048. Read article.

Spin-Crossover Behaviors Based on Intermolecular Interactions for Cobalt(II) Complexes with Long Alkyl Chains

2012-01-09T:+05:00

[Full Paper]
Yasuka Komatsu, Kazuya Kato, Yuuki Yamamoto, Hidenobu Kamihata, Young Hoon Lee, Akira Fuyuhiro, Satoshi Kawata, Shinya Hayami
Eur. J. Inorg. Chem., January 9, 2012, DOI: 10.1002/ejic.201101040. Read article.

Hierarchical Hydroxyapatite Microspheres Composed of Nanorods and Their Competitive Sorption Behavior for Heavy Metal Ions

Ronghai Zhu, Xiaoyong Lai, Jonathan E. Halpert, Ranbo Yu, Dan Wang — 2012-01-27T:+05:00

[Short Communication]
Ronghai Zhu, Xiaoyong Lai, Jonathan E. Halpert, Ranbo Yu, Dan Wang
Eur. J. Inorg. Chem., January 27, 2012, DOI: 10.1002/ejic.201101038. Read article.

Nickel-Catalyzed Cross-Coupling with Pincer Ligands

Zhong-Xia Wang, Ning Liu — 2012-01-16T:+05:00

[Microreview]
Zhong-Xia Wang, Ning Liu
Eur. J. Inorg. Chem., January 16, 2012, DOI: 10.1002/ejic.201101036. Read article.

A Systematic Study of Electrochemical and Spectral Properties for the Electronic Interactions in Porphyrin–Triphenylamine Conjugates

2012-01-30T:+05:00

[Full Paper]
Chih-Yen Huang, Chao-Yen Hsu, Luo-Yi Yang, Chia-Jung Lee, Te-Fang Yang, Chia-Chan Hsu, Chung-Hsiu Ke, Yuhlong Oliver Su
Eur. J. Inorg. Chem., January 30, 2012, DOI: 10.1002/ejic.201101033. Read article.

Ruthenium(III) Cyclometalates Obtained by Site-Specific Orthometallation and Their Reactivity with Nitric Oxide: Photoinduced Release and Estimation of NO Liberated from the Ruthenium Nitrosyl Complexes

Kaushik Ghosh, Sushil Kumar, Rajan Kumar, Udai P. Singh — 2012-01-23T:+05:00

[Full Paper]
Kaushik Ghosh, Sushil Kumar, Rajan Kumar, Udai P. Singh
Eur. J. Inorg. Chem., January 23, 2012, DOI: 10.1002/ejic.201101026. Read article.

Synthesis of β-Hydroxy and β-Amino Ketones from Allylic Alcohols Catalyzed by Ru(η⁵-C₅Ph₅)(CO)₂Cl

2011-12-29T:+05:00

[Full Paper]
Agnieszka Bartoszewicz, Martina M. Jeżowska, Kévin Laymand, Juri Möbus, Belén Martín-Matute
Eur. J. Inorg. Chem., December 29, 2011, DOI: 10.1002/ejic.201101014. Read article.

Kinetic and Mechanistic Studies on the Reactions of the Reduced Vitamin B₁₂ Complex Cob(I)alamin with Nitrite and Nitrate
Dedicated to the memory of Dr. Edwin S. Gould

Noah T. Plymale, Rohan S. Dassanayake, Hanaa A. Hassanin, Nicola E. Brasch — 2011-12-14T:+05:00

[Full Paper]
Noah T. Plymale, Rohan S. Dassanayake, Hanaa A. Hassanin, Nicola E. Brasch
Eur. J. Inorg. Chem., December 14, 2011, DOI: 10.1002/ejic.201100992. Read article.

Cyclopentadienyl-, Indenyl- and Fluorenyl-Functionalized N-Heterocyclic Carbene Metal Complexes: Synthesis and Catalytic Applications

Beatriz Royo, Eduardo Peris — 2011-11-30T:+05:00

[Microreview]
Beatriz Royo, Eduardo Peris
Eur. J. Inorg. Chem., November 30, 2011, DOI: 10.1002/ejic.201100990. Read article.

Graphitic Carbon Nanocapsules: Scaled Preparation, Formation Mechanism, and Use as an Excellent Support for Methanol Electro-oxidation

Lei Wang, Chungui Tian, Hongxing Zhang, Honggang Fu — 2012-01-18T:+05:00

[Full Paper]
Lei Wang, Chungui Tian, Hongxing Zhang, Honggang Fu
Eur. J. Inorg. Chem., January 18, 2012, DOI: 10.1002/ejic.201100988. Read article.

Synthesis and Reactivity of Ester-Functionalized 5-Membered Rh^I-κ²-C,O-Chelates and Their Relevance in Rh(cod)-Mediated Carbene Polymerization

Markus Finger, Martin Lutz, Joost N. H. Reek, Bas de Bruin — 2011-12-23T:+05:00

[Full Paper]
Markus Finger, Martin Lutz, Joost N. H. Reek, Bas de Bruin
Eur. J. Inorg. Chem., December 23, 2011, DOI: 10.1002/ejic.201100981. Read article.

Cationic Group 4 Metallocene–(o-Phosphanylaryl)oxido Complexes: Synthetic Routes to Transition-Metal Frustrated Lewis Pairs

Andy M. Chapman, Mairi F. Haddow, Duncan F. Wass — 2011-12-09T:+05:00

[Full Paper]
Andy M. Chapman, Mairi F. Haddow, Duncan F. Wass
Eur. J. Inorg. Chem., December 9, 2011, DOI: 10.1002/ejic.201100968. Read article.

Unexpected Outcomes of the Oxidation of (Pentafluorophenyl)triphenylphosphanegold(I)

Manuel Hofer, Cristina Nevado — 2011-11-28T:+05:00

[Short Communication]
Manuel Hofer, Cristina Nevado
Eur. J. Inorg. Chem., November 28, 2011, DOI: 10.1002/ejic.201100956. Read article.

An NMR Study of the Oxidative Degradation of Cp*Ir Catalysts for Water Oxidation: Evidence for a Preliminary Attack on the Quaternary Carbon Atom of the –C–CH₃ Moiety

2011-11-30T:+05:00

[Full Paper]
Cristiano Zuccaccia, Gianfranco Bellachioma, Sandra Bolaño, Luca Rocchigiani, Arianna Savini, Alceo Macchioni
Eur. J. Inorg. Chem., November 30, 2011, DOI: 10.1002/ejic.201100954. Read article.

Influence of Morphology and Texture of CeO₂ on YBa₂Cu₃O₇ (YBCO) Growth and BaCeO₃ Formation in Solution-Derived Synthesis

2012-02-03T:+05:00

[Full Paper]
Nigel Van de Velde, Tom Bruggeman, Lander Stove, Glenn Pollefeyt, Oliver Brunkahl, Isabel Van Driessche
Eur. J. Inorg. Chem., February 3, 2012, DOI: 10.1002/ejic.201100951. Read article.

New Structural Features in Tetranuclear Iron Carbonyl Thiocarbonyls: Exotriangular Iron Atoms and Six-Electron-Donoating Thiocarbonyl Groups Bridging Four Iron Atoms

Zhong Zhang, Qian-shu Li, R. Bruce King, Henry F. Schaefer, III — 2012-01-17T:+05:00

[Full Paper]
Zhong Zhang, Qian-shu Li, R. Bruce King, Henry F. Schaefer, III
Eur. J. Inorg. Chem., January 17, 2012, DOI: 10.1002/ejic.201100942. Read article.

Chelating C4-Bound Imidazolylidene Complexes through Oxidative Addition of Imidazolium Salts to Palladium(0)

2011-11-10T:+05:00

[Full Paper]
Anneke Krüger, Evelyne Kluser, Helge Müller-Bunz, Antonia Neels, Martin Albrecht
Eur. J. Inorg. Chem., November 10, 2011, DOI: 10.1002/ejic.201100940. Read article.

Fabrication of a 3D Hierarchical Flower-Like MgO Microsphere and Its Application as Heterogeneous Catalyst

2012-01-16T:+05:00

[Full Paper]
Yang Qu, Wei Zhou, Zhiyu Ren, Kai Pan, Chungui Tian, Yang Liu, Shanshan Feng, Youzhen Dong, Honggang Fu
Eur. J. Inorg. Chem., January 16, 2012, DOI: 10.1002/ejic.201100936. Read article.

The Nature of the Barrier to Phosphane Dissociation from Grubbs Olefin Metathesis Catalysts

Yury Minenkov, Giovanni Occhipinti, Wouter Heyndrickx, Vidar R. Jensen — 2011-12-21T:+05:00

[Full Paper]
Yury Minenkov, Giovanni Occhipinti, Wouter Heyndrickx, Vidar R. Jensen
Eur. J. Inorg. Chem., December 21, 2011, DOI: 10.1002/ejic.201100932. Read article.

Ruthenium Acetate Complexes as Versatile Probes of Metal–Ligand Interactions: Insight into the Ligand Effects of Vinylidene, Carbene, Carbonyl, Nitrosyl and Isocyanide

2011-12-21T:+05:00

[Full Paper]
Christine E. Welby, Thomas O. Eschemann, Christopher A. Unsworth, Elizabeth J. Smith, Robert J. Thatcher, Adrian C. Whitwood, Jason M. Lynam
Eur. J. Inorg. Chem., December 21, 2011, DOI: 10.1002/ejic.201100931. Read article.

Dinuclear and Mononuclear Chromium Acetylide Complexes
Dedicated to Professor Gerhard Erker on the occasion of his 65th birthday

2011-12-02T:+05:00

[Full Paper]
Carolina Egler-Lucas, Olivier Blacque, Koushik Venkatesan, Alberto López-Hernández, Heinz Berke
Eur. J. Inorg. Chem., December 2, 2011, DOI: 10.1002/ejic.201100929. Read article.

Arene Exchange in the Ruthenium–Naphthalene Complex [CpRu(C₁₀H₈)]⁺

2011-11-23T:+05:00

[Full Paper]
Dmitry S. Perekalin, Eduard E. Karslyan, Pavel V. Petrovskii, Alexandra O. Borissova, Konstantin A. Lyssenko, Alexander R. Kudinov
Eur. J. Inorg. Chem., November 23, 2011, DOI: 10.1002/ejic.201100928. Read article.

Unique Type of BF₂-Capped Tetraoxobenzene π-Complexes of “Cp*M”: Novel Organometallic Backbones for the Self-Assembly of Porous Networks

2011-10-24T:+05:00

[Short Communication]
Jamal Moussa, Aurélie Damas, Lise-Marie Chamoreau, Marie Noelle Rager, Hani Amouri
Eur. J. Inorg. Chem., October 24, 2011, DOI: 10.1002/ejic.201100927. Read article.

Synthesis of Ir[μ²-(N-N)]M (M = Ir and Ru) Homo- and Heterobimetallic Complexes through a Condensation Reaction of N-Amino and Formyl Groups Bound to Mononuclear (ηⁿ-C_nMe_n)M Units (n = 5 for M = Ir; n = 6 for M = Ru)

Keisuke Nakao, Gyeongshin Choi, Yuki Konishi, Hayato Tsurugi, Kazushi Mashima — 2011-12-07T:+05:00

[Full Paper]
Keisuke Nakao, Gyeongshin Choi, Yuki Konishi, Hayato Tsurugi, Kazushi Mashima
Eur. J. Inorg. Chem., December 7, 2011, DOI: 10.1002/ejic.201100925. Read article.

Synthesis and Characterization of Dioxidodiphenylrhenium(VII) Propionate

2011-10-25T:+05:00

[Short Communication]
Stefan Huber, Mirza Cokoja, Markus Drees, Wolfgang A. Herrmann, Fritz E. Kühn
Eur. J. Inorg. Chem., October 25, 2011, DOI: 10.1002/ejic.201100919. Read article.

Synthesis, Structure and Reactivity of Iridium Hydrido Fluorido Complexes

Paul Kläring, Ann-Katrin Jungton, Thomas Braun, Carsten Müller — 2011-12-21T:+05:00

[Full Paper]
Paul Kläring, Ann-Katrin Jungton, Thomas Braun, Carsten Müller
Eur. J. Inorg. Chem., December 21, 2011, DOI: 10.1002/ejic.201100917. Read article.

Straightforward Synthesis of Dipyrido-Annelated NHC-Palladium(II) Complexes by Oxidative Addition
Dedicated to Robert Weiss on the occasion of his 70th birthday

2012-01-17T:+05:00

[Full Paper]
Verena Gierz, Alexander Seyboldt, Cäcilia Maichle-Mössmer, Roland Fröhlich, Frank Rominger, Doris Kunz
Eur. J. Inorg. Chem., January 17, 2012, DOI: 10.1002/ejic.201100905. Read article.

New Acylhydrido- and Diacylrhodium(III) Organocomplexes Derived from 8-Quinolinecarbaldehyde and/or o-(Diphenylphosphanyl)benzaldehyde

2011-12-14T:+05:00

[Full Paper]
Montserrat Barquín, María A. Garralda, Ricardo Hernández, Lourdes Ibarlucea, Claudio Mendicute-Fierro, M. Carmen Torralba, M. Rosario Torres, Virginia San Nacianceno, Itziar Zumeta
Eur. J. Inorg. Chem., December 14, 2011, DOI: 10.1002/ejic.201100904. Read article.

Lanthanide Complexes as Paramagnetic Probes for ¹⁹F Magnetic Resonance

Peter Harvey, Ilya Kuprov, David Parker — 2011-11-08T:+05:00

[Microreview]
Peter Harvey, Ilya Kuprov, David Parker
Eur. J. Inorg. Chem., November 8, 2011, DOI: 10.1002/ejic.201100894. Read article.

Hydroalumination of Bis(alkynyl)silanes: Generation of Chelating Lewis Acids, Their Application in the Coordination of Chloride Ions and a 1,1-Carbalumination Reaction

2011-11-07T:+05:00

[Full Paper]
Werner Uhl, Denis Heller, Jutta Kösters, Ernst-Ulrich Würthwein, Nugzar Ghavtadze
Eur. J. Inorg. Chem., November 7, 2011, DOI: 10.1002/ejic.201100890. Read article.

Group 10 Metal Complexes of a Ferrocene-Based N-Heterocyclic Carbene: Syntheses, Structures and Catalytic Applications
Dedicated to Professor Dirk Steinborn on the occasion of his 65th birthday

2011-10-17T:+05:00

[Full Paper]
Ulrich Siemeling, Christian Färber, Clemens Bruhn, Sven Fürmeier, Tim Schulz, Michael Kurlemann, Sandra Tripp
Eur. J. Inorg. Chem., October 17, 2011, DOI: 10.1002/ejic.201100856. Read article.

Structural Heterogeneity of Ag^I Complexes with a Flexible 1,2-Bis[(imidazol-2-yl)thiomethyl]benzene Ligand and Issues Regarding the Phase Purity of the Bulk Material

Liliana Dobrzańska — 2012-01-23T:+05:00

[Full Paper]
Liliana Dobrzańska
Eur. J. Inorg. Chem., January 23, 2012, DOI: 10.1002/ejic.201100853. Read article.

Two Environmentally Friendly Energetic Compounds, [Mn(AZT)₄(H₂O)₂](PA)₂·4H₂O and [Co(AZT)₂(H₂O)₄](PA)₂, Based on 3-Azido-1,2,4-triazole (AZT) and Picrate (PA)

Bi-Dong Wu, Jian-Guo Zhang, Tong-Lai Zhang, Li Yang, Zun-Ning Zhou — 2012-02-03T:+05:00

[Full Paper]
Bi-Dong Wu, Jian-Guo Zhang, Tong-Lai Zhang, Li Yang, Zun-Ning Zhou
Eur. J. Inorg. Chem., February 3, 2012, DOI: 10.1002/ejic.201100806. Read article.

Cyclopentadienyl–NHC Iron Complexes for Solvent-Free Catalytic Hydrosilylation of Aldehydes and Ketones

2011-10-14T:+05:00

[Short Communication]
David Bézier, Fan Jiang, Thierry Roisnel, Jean-Baptiste Sortais, Christophe Darcel
Eur. J. Inorg. Chem., October 14, 2011, DOI: 10.1002/ejic.201100762. Read article.

[n]Borametalloarenophanes (n = 1, 2): Strained Systems with Uncommon Reactivity Patterns

Holger Braunschweig, Thomas Kupfer — 2011-10-27T:+05:00

[Microreview]
Holger Braunschweig, Thomas Kupfer
Eur. J. Inorg. Chem., October 27, 2011, DOI: 10.1002/ejic.201100609. Read article.

Synthesis of Furfural from Xylose, Xylan, and Biomass Using AlCl₃·6 H₂O in Biphasic Media via Xylose Isomerization to Xylulose

Yu Yang, Chang-Wei Hu, Mahdi M. Abu-Omar — 2012-02-07T:+05:00

Aluminum in microwaves: AlCl₃·6 H₂O successively hydrolyzes biomass hemicellulose to xylose, isomerizes xylose to xylulose, and dehydrates xylulose to furfural under microwave heating at 160 °C with yields in the range of 38–64 %, depending on the biomass feedstock. The use of a biphasic medium allows the recycling of AlCl₃·6 H₂O (which remains in the aqueous phase) for multiple cycles without loss of activity or selectivity (see figure).

[Full Paper]
Yu Yang, Chang-Wei Hu, Mahdi M. Abu-Omar
ChemSusChem, February 7, 2012, DOI: 10.1002/cssc.201100688. Read article.

Solid Acid-Catalyzed Cellulose Hydrolysis Monitored by In Situ ATR-IR Spectroscopy

Joseph Zakzeski, Ruud J. H. Grisel, Arjan T. Smit, Bert M. Weckhuysen — 2012-02-07T:+05:00

Vibrating acids: The solid acid-catalyzed hydrolysis of cellulose has been studied by using in situ ATR-IR spectroscopy. It is possible to monitor the formation and consumption of important products and intermediates by their distinctive vibrational characteristics under the reaction conditions.

[Full Paper]
Joseph Zakzeski, Ruud J. H. Grisel, Arjan T. Smit, Bert M. Weckhuysen
ChemSusChem, February 7, 2012, DOI: 10.1002/cssc.201100631. Read article.

Improved Li-Storage Performance of Li₄Ti₅O₁₂ Coated with C-N Compounds Derived from Pyrolysis of Urea through a Low-Temperature Approach

Huilin Pan, Liang Zhao, Yong-Sheng Hu, Hong Li, Liquan Chen — 2011-12-06T:+05:00

The wonders of urea: The porous Li₄Ti₅O₁₂ coated with C-N compound is prepared by pyrolysis of urea at a rather low temperature of 400 °C. The coated Li₄Ti₅O₁₂ sample shows improved rate performance and excellent capacity retention after 2000 cycles at a current rate of 2C in a half cell.

[Communication]
Huilin Pan, Liang Zhao, Yong-Sheng Hu, Hong Li, Liquan Chen
ChemSusChem, December 6, 2011, DOI: 10.1002/cssc.201100629. Read article.

Hollow Carbon Nanospheres with a High Rate Capability for Lithium-Based Batteries

2012-01-19T:+05:00

Higher spheres: Hollow carbon nanospheres are prepared from glucose through a facile, sustainable hydrothermal method. Their morphology provides fast electron and lithium ion transport, which is reflected in a superior rate capability (100 mAh g⁻¹ at 50 C) and good cycle stability. Nevertheless, these results provide direct evidence that not only lithium-ion insertion/extraction to the carbon layers occurs, but also that a surface reaction contributes to the high rate performance.

[Communication]
Kun Tang, Robin J. White, Xiaoke Mu, Maria-Magdalena Titirici, Peter A. van Aken, Joachim Maier
ChemSusChem, January 19, 2012, DOI: 10.1002/cssc.201100609. Read article.

Conversion of Hemicellulose to Furfural and Levulinic Acid using Biphasic Reactors with Alkylphenol Solvents

Elif I. Gürbüz, Stephanie G. Wettstein, James A. Dumesic — 2012-01-24T:+05:00

Plans with plants: The hemicellulose fraction of lignocellulosic biomass is converted to furfural and levulinic acid using biphasic reactors with alkylphenol solvents that selectively partition furanic compounds from acidic aqueous solutions. The furfural and levulinic acid products are valuable compounds for a variety of chemical applications, and they serve as precursors for the synthesis of liquid transportation fuels.

[Communication]
Elif I. Gürbüz, Stephanie G. Wettstein, James A. Dumesic
ChemSusChem, January 24, 2012, DOI: 10.1002/cssc.201100608. Read article.

Amine Synthesis through Mild Catalytic Hydrosilylation of Imines using Polymethylhydroxysiloxane and [RuCl₂(arene)]₂ Catalysts

Bin Li, Jean-Baptiste Sortais, Christophe Darcel, Pierre H. Dixneuf — 2012-02-03T:+05:00

Tolerate silicone! The stable [RuCl₂(p-cymene]₂ complex is an efficient catalyst for the direct chemoselective hydrosilylation of functionalized aldimines and ketimines into amines, using polymethylhydroxysiloxane as an inexpensive, stable, and safe hydrosilane source. The catalysis operates in ethanol, under air at room temperature, and tolerates the ketone ester and alkene functionality.

[Communication]
Bin Li, Jean-Baptiste Sortais, Christophe Darcel, Pierre H. Dixneuf
ChemSusChem, February 3, 2012, DOI: 10.1002/cssc.201100585. Read article.

A Solid-Supported Organocatalyst for Continuous-Flow Enantioselective Aldol Reactions

Carles Ayats, Andrea H. Henseler, Miquel A. Pericàs — 2012-01-02T:+05:00

Go with the flow! A novel 4-(1-triazolyl)proline immobilized onto 8 % DVB-PS catalyzes highly stereoselective aldol reactions under continuous flow conditions with very low catalyst loading (TON up to 61). Up to four different enantiomerically pure aldol products can be sequentially produced in gram amounts with the same catalyst sample.

[Full Paper]
Carles Ayats, Andrea H. Henseler, Miquel A. Pericàs
ChemSusChem, January 2, 2012, DOI: 10.1002/cssc.201100570. Read article.

A High-Energy-Density Redox Flow Battery based on Zinc/Polyhalide Chemistry

Liqun Zhang , Qinzhi Lai, Jianlu Zhang, Huamin Zhang — 2012-01-19T:+05:00

Zn and the Art of Battery Development: A zinc/polyhalide redox flow battery employs Br⁻/ClBr²⁻ and Zn/Zn²⁺ redox couples in its positive and negative half-cells, respectively. The performance of the battery is evaluated by charge–discharge cycling tests and reveals a high energy efficiency of 81%, based on a Coulombic efficiency of 96% and voltage efficiency of 84%. The new battery technology can provide high performance and energy density at an acceptable cost.

[Communication]
Liqun Zhang , Qinzhi Lai, Jianlu Zhang, Huamin Zhang
ChemSusChem, January 19, 2012, DOI: 10.1002/cssc.201100530. Read article.

CO Oxidation at the Perimeters of an FeO/Pt(111) Interface and how Water Promotes the Activity: A First-Principles Study

Xiang-Kui Gu, Runhai Ouyang, Dapeng Sun, Hai-Yan Su, Wei-Xue Li — 2011-12-09T:+05:00

An active ensemble: The Pt-Fe cation ensemble hosted in the perimeters of FeO islands supported on Pt provides active sites for O₂ and H₂O activation free from CO poison. The Pt-Fe cation ensemble is highly active for CO oxidation, the activity of which is further promoted by water (see picture).

[Full Paper]
Xiang-Kui Gu, Runhai Ouyang, Dapeng Sun, Hai-Yan Su, Wei-Xue Li
ChemSusChem, December 9, 2011, DOI: 10.1002/cssc.201100525. Read article.

Mechanistic Investigation on the Formation and Dehydrogenation of Calcium Amidoborane Ammoniate

2012-01-31T:+05:00

Amidoborane ammoniate formation is investigated by using isotopic labeling techniques. The formation of Ca(NH₂BH₃)₂·2 NH₃ is initiated by proton transfer from NH₃BH₃ to NH₂⁻ (amide), forming Ca(NH₃)²⁺ and anionic [NH₂BH₃]⁻ groups. The dehydrogenation of the ammoniate, which occurs at lower temperatures, is a result of the participation of NH₃ in the dehydrogenation process via the combination of (NH₃)H^δ+···H^δ−(NH₂BH₃⁻).

[Full Paper]
Yong Shen Chua, Wen Li, Wendy J. Shaw, Guotao Wu, Tom Autrey, Zhitao Xiong, Ming Wah Wong, Ping Chen
ChemSusChem, January 31, 2012, DOI: 10.1002/cssc.201100523. Read article.

Application of the Sol–Gel Technique to Develop Synthetic Calcium-Based Sorbents with Excellent Carbon Dioxide Capture Characteristics

Marcin Broda, Agnieszka M. Kierzkowska, Christoph R. Müller — 2012-02-01T:+05:00

Catch your breath: We report the development of synthetic calcium-based CO₂ sorbents using a sol–gel technique. We are able to synthesize a nanostructured material that possesses a high surface area and pore volume and shows excellent CO₂ capture characteristics over many cycles (see picture).

[Full Paper]
Marcin Broda, Agnieszka M. Kierzkowska, Christoph R. Müller
ChemSusChem, February 1, 2012, DOI: 10.1002/cssc.201100468. Read article.

Transfer of the Epoxidation of Soybean Oil from Batch to Flow Chemistry Guided by Cost and Environmental Issues

2012-01-27T:+05:00

Transfer window: A holistic concept for sustainable process development through process intensification due to microprocess technology in combination with novel process windows is presented. Process modeling and simulation linked with simplified cost and lifecycle assessment provide valuable information to guide the ongoing design of a continuously running pilot-process for the epoxidation of soybean oil (see picture).

[Full Paper]
Dana Kralisch, Ina Streckmann, Denise Ott, Ulich Krtschil, Elio Santacesaria, Martino Di Serio, Vincenzo Russo, Lucrezia De Carlo, Walter Linhart, Engelbert Christian, Bruno Cortese, Mart H. J. M. de Croon, Volker Hessel
ChemSusChem, January 27, 2012, DOI: 10.1002/cssc.201100445. Read article.

Application of Metal-Based Reagents and Catalysts in Microstructured Flow Devices

2012-01-24T:+05:00

Down and up: Downscaling reaction vessels and moving to a continuous flow approach have not only advanced many reactions with respect to efficiency and safety, but also offer a reliable solution for upscaling chemical transformations. Examples in this Minireview demonstrate the use of sensitive metal-based reagents, substrates, and catalysts at extreme temperatures.

[Minireview]
Tamilselvi Chinnusamy, Salprima Yudha S , Markus Hager, Peter Kreitmeier, Oliver Reiser
ChemSusChem, January 24, 2012, DOI: 10.1002/cssc.201100444. Read article.

A Capsule Catalyst with a Zeolite Membrane Prepared by Direct Liquid Membrane Crystallization

2012-01-27T:+05:00

A sheltered existence: Direct liquid-membrane crystallization is used as a low-cost, low-waste, yet highly effective method to prepare a catalyst encapsulated by a H-β zeolite. Through vapor–liquid exchange, a continuous and sufficient, but not excessive supply of both water and template is the key part of this method.

[Communication]
Chunlin Li, Hengyong Xu, Yuko Kido, Yoshiharu Yoneyama, Yoshifumi Suehiro, Noritatsu Tsubaki
ChemSusChem, January 27, 2012, DOI: 10.1002/cssc.201100431. Read article.

Flexible and Platinum-Free Dye-Sensitized Solar Cells with Conducting-Polymer-Coated Graphene Counter Electrodes

Kun Seok Lee, Youngbin Lee, Jun Young Lee, Jong-Hyun Ahn, Jong Hyeok Park — 2012-01-13T:+05:00

Always wear a coat: On a plastic substrate graphene is coated with a conducting polymer (PEDOT), resulting in a flexible composite film. The film is used as counter electrode in dye-sensitized solar cells (DSSCs) instead of platinum/transparent conducting oxides (TCOs). The performance of the TCO- and platinum-free counter electrode rivals that of convenential DSSCs.

[Communication]
Kun Seok Lee, Youngbin Lee, Jun Young Lee, Jong-Hyun Ahn, Jong Hyeok Park
ChemSusChem, January 13, 2012, DOI: 10.1002/cssc.201100430. Read article.

Design of Cellulose Dissolving Ionic Liquids Inspired by Nature

2012-01-19T:+05:00

Stimulating the hunger of enzymes: The design of an ionic liquid that have the ability to dissolve cellulose has been attempted from the viewpoint of a cellulase. N,N-diethyl-N-(2-methoxyethyl)-N-methylammonium alanine ([N_221ME][Ala]) is a good solvent for cellulose. Dissolution in [N_221ME][Ala] converts the crystalline structure of cellulose from Type I to II, which is known to be a form easily digested by cellulases.

[Communication]
Kazutaka Ohira, Yoshikazu Abe, Motoi Kawatsura, Kazuhiko Suzuki, Masahiro Mizuno, Yoshihiko Amano, Toshiyuki Itoh
ChemSusChem, January 19, 2012, DOI: 10.1002/cssc.201100427. Read article.

Sequential Continuous flow Processes for the Oxidation of Amines and Azides by using HOF·MeCN

Christopher B. McPake, Christopher B. Murray, Graham Sandford — 2011-12-13T:+05:00

Oxidation in flow: The oxidation of amines and azides to the corresponding nitrated systems by using fluorine gas, water and acetonitrile by sequential gas–liquid/liquid–liquid continuous flow procedures are reported.

[Full Paper]
Christopher B. McPake, Christopher B. Murray, Graham Sandford
ChemSusChem, December 13, 2011, DOI: 10.1002/cssc.201100423. Read article.

Development of Polymeric Palladium-Nanoparticle Membrane-Installed Microflow Devices and their Application in Hydrodehalogenation

Yoichi M. A. Yamada, Toshihiro Watanabe, Aya Ohno, Yasuhiro Uozumi — 2012-01-13T:+05:00

Streamlined nanoparticles: We developed a variety of polymeric Pd nanoparticle membrane-installed microflow devices. Instantaneous hydrodehalogenation of aryl halides can be achieved at short residence times and moderate temperatures using a safe, nonexplosive aqueous sodium formate to quantitatively afford the corresponding hydrodehalogenated products. PCB and PBB can also be fully decomposed under similar conditions to give a biphenyl.

[Full Paper]
Yoichi M. A. Yamada, Toshihiro Watanabe, Aya Ohno, Yasuhiro Uozumi
ChemSusChem, January 13, 2012, DOI: 10.1002/cssc.201100418. Read article.

New Biobased High Functionality Polyols and Their Use in Polyurethane Coatings

Xiao Pan, Dean C. Webster — 2012-01-23T:+05:00

Sweet resins: Sucrose soyate based polyols are made from sucrose esters of soybean oil through epoxidation and epoxide ring-opening reactions (see picture). These new biobased high functionality polyols are biomacromolecules with an innovative structural concept: well-defined compact structure, rigid sucrose core, and high hydroxyl group functionality.

[Full Paper]
Xiao Pan, Dean C. Webster
ChemSusChem, January 23, 2012, DOI: 10.1002/cssc.201100415. Read article.

Recent Changes in Patenting Behavior in Microprocess Technology and its Possible Use for Gas–Liquid Reactions and the Oxidation of Glucose

2012-01-25T:+05:00

It got patential flow: Patenting behavior in microprocess technology has been changed during the last five years. The importance of multiphase reactions in chemical and pharmaceutical industry is shown by an increased number of device and process patents in this field. However, reviewed patents indicate that dealing with solid catalyst and flow control are still challenging tasks.

[Review]
Ivana Dencic, Volker Hessel, Mart H. J. M. de Croon, Jan Meuldijk, Christianus W. J. van der Doelen, Kasper Koch
ChemSusChem, January 25, 2012, DOI: 10.1002/cssc.201100389. Read article.

Practical Synthesis of Photochromic Diarylethenes in Integrated Flow microreactor Systems

Tatsuro Asai, Atsushi Takata, Aiichiro Nagaki, Jun-ichi Yoshida — 2011-11-08T:+05:00

Too successful to be cool: An effective method for the synthesis of photochromic diarylethenes has been developed by using integrated flow microreactor systems. Reactions can be conducted without the need for cryogenic conditions by using these systems (see picture). The synthesis of unsymmetrical diarylethenes, which is difficult to achieve by using conventional macro batch systems, has also been accomplished.

[Full Paper]
Tatsuro Asai, Atsushi Takata, Aiichiro Nagaki, Jun-ichi Yoshida
ChemSusChem, November 8, 2011, DOI: 10.1002/cssc.201100376. Read article.

Room-Temperature, Acid-Catalyzed [2+2] Cycloadditions: Suppression of Side Reactions by using a Flow Microreactor System

Kei Kurahashi, Yoshiji Takemoto, Kiyosei Takasu — 2011-10-27T:+05:00

Added value: The [2+2] cycloaddition of silyl enol ethers with α,β-unsaturated esters, catalyzed by the superstrong acid triflic imide (Tf₂NH), at room temperature in a flow microreactor system is reported. The micororeactor method achieves the [2+2] cycloaddition of unstable silyl enol ethers and acrylates, which is unsuccessful batch reactors, even at room temperature.

[Communication]
Kei Kurahashi, Yoshiji Takemoto, Kiyosei Takasu
ChemSusChem, October 27, 2011, DOI: 10.1002/cssc.201100373. Read article.

Ritter Reactions in Flow

Logan Audiger, Kevin Watts, Simon C. Elmore, Richard I. Robinson, Thomas Wirth — 2011-12-01T:+05:00

Flow me a Ritter: Ritter reactions are performed in a simple microreactor setup using tert-butylacetate as versatile carbocation source. The protocol avoids the handling of large amounts of hot concentrated sulfuric acid as low concentrations are optimal for rapid access tert-butyl- or diphenylmethyl-protected amides.

[Communication]
Logan Audiger, Kevin Watts, Simon C. Elmore, Richard I. Robinson, Thomas Wirth
ChemSusChem, December 1, 2011, DOI: 10.1002/cssc.201100372. Read article.

Solid-Supported Gallium Triflate: An Efficient Catalyst for the Three-component Ketonic Strecker Reaction

Charlotte Wiles, Paul Watts — 2011-12-08T:+05:00

Trifle gallium supporters: A solidsupported gallium triflate derivative is synthesized and screened for activity towards the ketonic Strecker reaction. The target α-aminonitriles are obtained in higher yield and purity compared to reactions reported in literature, for which the analogous homogeneous catalyst is used.

[Full Paper]
Charlotte Wiles, Paul Watts
ChemSusChem, December 8, 2011, DOI: 10.1002/cssc.201100370. Read article.

Highly Proton-Selective Biopolymer Layer-Coated Ion-Exchange Membrane for Direct Methanol Fuel Cells

2012-02-03T:+05:00

Peels of an onion: New composite proton exchange membranes prepared through layer-by-layer coating of a biopolymer has shown superior methanol barrier properties, while maintaining a high affinity to proton transfer same time. The highly selective skin layer in the composite system significantly increases the fuel utilization efficiency in direct methanol fuel cells (DMFCs).

[Communication]
Sanna Kotrappanavar Nataraj, Chen-Hao Wang, Hsin-Chih Huang, He-Yun Du, Sea-Fu Wang, Ying-Chu Chen, Li-Chyong Chen, Kuei-Hsien Chen
ChemSusChem, February 3, 2012, DOI: 10.1002/cssc.201100366. Read article.

Prilezhaev Dihydroxylation of Olefins in a Continuous Flow Process

2011-12-01T:+05:00

Olefins go with the flow: Prilezhaev dihydroxylation can be performed on a large scale in continuous flow microreactor systems in the oxidation of terminal and internal olefins. Major drivers for a continuous flow process include better control, improved safety, and a faster overall process, leading to a significantly higher throughput.

[Full Paper]
Bas A. M. W. van den Broek, René Becker, Florian Kössl, Mariëlle M. E. Delville, Pieter J. Nieuwland, Kaspar Koch, Floris P. J. T. Rutjes
ChemSusChem, December 1, 2011, DOI: 10.1002/cssc.201100342. Read article.

The Oxygen-Mediated Synthesis of 1,3-Butadiynes in Continuous Flow: Using Teflon AF-2400 to Effect Gas/Liquid Contact

2011-09-21T:+05:00

The gas is always greener: A continuous flow Glaser–Hay coupling reaction system, mediated by molecular oxygen, is developed based on a tube-in-tube gas/liquid reactor/injector. The system uses a semi-permeable Teflon AF-2400 membrane to effect rapid gas/liquid contact in flow, affording homogeneous solutions of oxygen. Measurements of out-gassing downstream of the back-pressure regulator indicate the onset of saturation is reached after ca. 16 seconds.

[Communication]
Trine P. Petersen, Anastasios Polyzos , Matthew O’Brien, Trond Ulven, Ian R. Baxendale, Steven V. Ley
ChemSusChem, September 21, 2011, DOI: 10.1002/cssc.201100339. Read article.

Highly Efficient 1,4-Addition of Aldehydes to Nitroolefins: Organocatalysis in Continuous Flow by Solid-Supported Peptidic Catalysts

2012-02-01T:+05:00

Michael’s peptides: A simple and efficient continuous flow technique has been developed for the organocatalytic Michael reactions using solid-supported peptidic catalysts, readily synthesized and immobilized in one single step. Synthetically useful chiral γ-nitroaldehydes have been obtained in excellent yields and stereoselectivities within short reaction times, while catalyst reusability, the ease of product isolation, and facile scale-up enhances the efficacy of the technique.

[Communication]
Sándor B. Ötvös, István M. Mándity, Ferenc Fülöp
ChemSusChem, February 1, 2012, DOI: 10.1002/cssc.201100332. Read article.

Homogeneous Photocatalytic Reactions with Organometallic and Coordination Compounds—Perspectives for Sustainable Chemistry

Norbert Hoffmann — 2012-01-27T:+05:00

Solar powered: Photochemical conditions significantly alter the outcome of chemical reactions. Consequently, the scope of catalytic transformations with organometallic and coordination compounds is also considerably enlarged. This article provides a short overview on such reactions and their application to organic synthesis. The review also indicates synergistic effects of photochemistry and catalysis with perspectives for a sustainable chemistry.

[Review]
Norbert Hoffmann
ChemSusChem, January 27, 2012, DOI: 10.1002/cssc.201100286. Read article.

Hydrogen Evolution from Water/Alcohol Mixtures: Effective In Situ Generation of an Active Au/TiO₂ catalyst

2011-10-27T:+05:00

Gold standard: Au/TiO₂ catalysts, easily prepared in situ from different Au precursors and TiO₂, generate hydrogen from water/alcohol mixtures. Different alcohols, and even glucose, can serve as sacrificial reductants. The best system produces hydrogen on a liter scale, and is stable for more than two days. Deuteration studies show that proton reduction is likely the rate-limiting step in this reaction.

[Communication]
Felix Gärtner, Sebastian Losse, Albert Boddien, Marga-Martina Pohl, Stefania Denurra, Henrik Junge, Matthias Beller
ChemSusChem, October 27, 2011, DOI: 10.1002/cssc.201100281. Read article.

Organocatalyzed Epoxidation of Alkenes in Continuous Flow using a Multi-Jet Oscillating Disk Reactor

Raffaele Spaccini, Lucia Liguori, Carlo Punta, Hans-René Bjørsvik — 2011-10-12T:+05:00

The times are changing: A batch process, the Minisci epoxidation, is transformed into a continuous-flow protocol for the selective aerobic radical epoxidation of alkenes. The use of a novel reactor type allows to considerably shorten reactor residence times. Experimental results suggest that two different reaction mechanisms exist for the oxidation: one for the batch conditions and a different one for the flow synthesis protocol.

[Communication]
Raffaele Spaccini, Lucia Liguori, Carlo Punta, Hans-René Bjørsvik
ChemSusChem, October 12, 2011, DOI: 10.1002/cssc.201100262. Read article.

Energy from Plants and Microorganisms: Progress in Plant–Microbial Fuel Cells

Huan Deng, Zheng Chen, Feng Zhao — 2011-12-09T:+05:00

Down to the roots: Plant–microbial fuel cells convert solar energy into electrical power by using microorganisms, which degrade root exudates and pollutants at the anode and pass the electrons to acceptors at the cathode. This setup can provide auxiliary power while reducing the emission of greenhouse gas, that is, methane, from fields.

[Minireview]
Huan Deng, Zheng Chen, Feng Zhao
ChemSusChem, December 9, 2011, DOI: 10.1002/cssc.201100257. Read article.

ChemPlusChem – A Genuinely Multidisciplinary Journal of Chemistry & Materials

2011-09-26T:+05:00

[Call for Papers]

ChemPlusChem, September 26, 2011, DOI: 10.1002/cplu.201190001. Read article.

Porous Frameworks Based on Carborane–Ln₂(CO₂)₆: Architecture Influenced by Lanthanide Contraction and Selective CO₂ Capture

Sheng-Li Huang, Yue-Jian Lin, Wei-Bin Yu, Guo-Xin Jin — 2012-01-25T:+05:00

Cast your net widely: Three distinct structure types of porous frameworks based on carborane–Ln₂(CO₂)₆ (structure type I with Schläfli symbol of 4⁴·6², structure type II with Schläfli symbol of (4⁸·6⁶·8)(4⁸·6⁶·8), and structure type III with Schläfli symbol of 4¹²·6³) have been synthesized and structurally characterized (see figure). Gas sorption was studied and selective CO₂ capture over CH₄ and N₂ was observed.

[Full Paper]
Sheng-Li Huang, Yue-Jian Lin, Wei-Bin Yu, Guo-Xin Jin
ChemPlusChem, January 25, 2012, DOI: 10.1002/cplu.201100083. Read article.

Scaffold-Optimized Dendrimers for the Detection of the Triacetone Triperoxide Explosive Using Quartz Crystal Microbalances

2012-01-25T:+05:00

Affinity and selectivity: The online detection of the explosive triacetone triperoxide (TATP) is an utmost challenge in security research. The great number of events wherein TATP was involved underlines the significance of solutions to trace that particular explosive material. New optimized functionalized polyphenylene dendrimers (see structure) have been synthesized that can be used as powerful affinity systems to trace TATP on a ppb level.

[Communication]
Daniel Lubczyk, Matthias Grill, Martin Baumgarten, Siegfried R. Waldvogel, Klaus Müllen
ChemPlusChem, January 25, 2012, DOI: 10.1002/cplu.201100080. Read article.

Identifying the Decomposition Product of Single-Source Precursors: Towards Water-Soluble Quantum Dots

Mark Green, Lydia Sandiford, Kirsty M. Anderson, Yongmin Ma — 2012-01-31T:+05:00

On the dot: A water-soluble single-source precursor has been used in the synthesis of CdS quantum dots passivated with a nucleotide in an aqueous one-pot reaction (see figure). The crystal structure of the decomposition product of a single-source precursor, 3-methyl-5-(1,2,3,4-tetra hydroxybutyl)oxazolidine-2-thione is also presented. A new decomposition mechanism is suggested that compliments existing routes.

[Communication]
Mark Green, Lydia Sandiford, Kirsty M. Anderson, Yongmin Ma
ChemPlusChem, January 31, 2012, DOI: 10.1002/cplu.201100076. Read article.

Synthesis and Stability of Highly Crystalline and Stable Iron/Iron Oxide Core/Shell Nanoparticles for Biomedical Applications

2012-01-20T:+05:00

Strike while the iron is hot: Stable core/shell nanoparticles of single-crystal iron core are shown to produce much greater contrast enhancement in magnetic resonance imaging of cells, compared to that produced by pure iron oxides without increase in cytotoxicity (see TEM image of iron/iron oxide nanoparticles).

[Full Paper]
Soshan Cheong, Peter Ferguson, Ian F. Hermans, Guy N. L. Jameson, Sujay Prabakar, David A. J. Herman, Richard D. Tilley
ChemPlusChem, January 20, 2012, DOI: 10.1002/cplu.201100074. Read article.

Influence of the Second Coordination Shell on the XANES Spectra of the Zn²⁺ Ion in Water and Methanol.

Valentina Migliorati, Andrea Zitolo, Giovanni Chillemi, Paola D'Angelo — 2012-01-26T:+05:00

Come out of your shell: Molecular dynamics simulations and X-ray absorption near-edge structure (XANES) spectroscopy have been used to investigate the coordination properties of the Zn²⁺ ion in water and methanol (see graphs; Zn cyan). XANES is sensitive to water molecules in the second hydration shell, meanwhile second-shell methanol molecules provide a negligible contribution. This finding is related to the different structuring ability of the two solvents.

[Full Paper]
Valentina Migliorati, Andrea Zitolo, Giovanni Chillemi, Paola D'Angelo
ChemPlusChem, January 26, 2012, DOI: 10.1002/cplu.201100070. Read article.

(−)-(1R,2R,7S,8aR)-1,2,7-Trihydroxyindolizidine ((−)-7S-OH-Lentiginosine): Synthesis and Proapoptotic Activity

2012-02-06T:+05:00

Indolizidine alkaloids: Highly selective and reproducible tert-butylation of enantiopure N-benzyl dihydroxypyrrolidine was exploited in an improved synthesis of 3,4-bis-tert-butoxypyrroline N-oxide for the synthesis of (−)-7S-OH-lentiginosine (see scheme; Bn=benzyl). The introduction of an additional hydroxy group on C7 of the non-natural lentiginosine provides another example of an efficient apoptosis inducer with low cytotoxicity.

[Full Paper]
Franca M. Cordero, Paola Bonanno, Bhushan B. Khairnar, Francesca Cardona, Alberto Brandi, Beatrice Macchi, Antonella Minutolo, Sandro Grelli, Antonio Mastino
ChemPlusChem, February 6, 2012, DOI: 10.1002/cplu.201100069. Read article.

Sequential Immobilization of Enzymes in Microfluidic Channels for Cascade Reactions

2012-01-20T:+05:00

Go with the flow: A flow-through microfluidic reactor system was developed that contained the three enzymes, β-galactosidase (β-Gal), glucose oxidase (GOD), and peroxidase (HRP), immobilized with a polycationic dendronized polymer in a predetermined sequence on a single chip for the conduction of an enzymatic cascade reaction. The desired enzyme localization within the microchannels of the chip could be achieved with a micromechanical valve system.

[Communication]
Sara Fornera, Phillip Kuhn, Dario Lombardi, A. Dieter Schlüter, Petra S. Dittrich, Peter Walde
ChemPlusChem, January 20, 2012, DOI: 10.1002/cplu.201100068. Read article.

Facile One-pot Synthesis of ZnO/SnO₂ Heterojunction Photocatalysts with Excellent Photocatalytic Activity and Photostability

2012-01-25T:+05:00

It's all about performance: ZnO/SnO₂ heterojunction nanocatalysts (see the formation of a ZnO/SnO₂ heterojunction in the TEM image) with excellent photocatalytic performances have been synthesized through a simple one-pot solvothermal method. The relationship between their structure and photocatalytic performances, especially antiphotocorrosion property, has been systematically studied.

[Full Paper]
Lirong Zheng, Yuanhui Zheng, Chongqi Chen, Yingying Zhan, Xinyi Lin, Qi Zheng, Kemei Wei
ChemPlusChem, January 25, 2012, DOI: 10.1002/cplu.201100066. Read article.

DNA “Nanolamps”: “Clicked” DNA Conjugates with Photon Upconverting Nanoparticles as Highly Emissive Biomaterial

2012-01-25T:+05:00

Upconverting DNA: Upconversion nanoparticles are ligated to oligonucleotides by using “click”-type cycloaddition (see figure). Excitation in the near-infrared region yields bright luminescence of the DNA conjugates in the visible range.

[Full Paper]
Moritz M. Rubner, Daniela E. Achatz, Heike S. Mader, Judith A. Stolwijk, Joachim Wegener, Gregory S. Harms, Otto S. Wolfbeis, Hans-Achim Wagenknecht
ChemPlusChem, January 25, 2012, DOI: 10.1002/cplu.201100055. Read article.

Facile and Low-Cost Synthesis of Large-Area Pure V₂O₅ Nanosheets for High-Capacity and High-Rate Lithium Storage over a Wide Temperature Range

Zhong-li Wang, Dan Xu, Li-min Wang, Xin-bo Zhang — 2012-01-09T:+05:00

Layer upon layer: Pure V₂O₅ nanosheets (see figure; C) have been successfully synthesized by a novel and facile dissolution–splitting method using low-cost raw materials (A). The as-prepared product exhibits enhanced lithium storage properties including good cycling and rate performance, 144 mAh g⁻¹ at 10 C and 95 mAh g⁻¹ at 20 C, as well as high reversible capacity, 290 mAh g⁻¹.

[Full Paper]
Zhong-li Wang, Dan Xu, Li-min Wang, Xin-bo Zhang
ChemPlusChem, January 9, 2012, DOI: 10.1002/cplu.201100051. Read article.

Tweezer-like Complexes of Crown Ethers with Divalent Metals: Probing Cation-Size-Dependent Conformations by Vibrational Spectroscopy in the Gas Phase

2012-01-11T:+05:00

Molecular tweezers in the gas phase: Isolated tweezer-like ternary complexes comprising two [18]crown-6 cyclic ether molecules and one divalent cation of varying size (Cu²⁺, Ca²⁺, Ba²⁺; see structures) have been investigated by means of laser vibrational action spectroscopy and computations. A remarkable dependence of the structure of the complexes with the size of the cation is observed.

[Full Paper]
Francisco Gámez, Paola Hurtado, Said Hamad, Bruno Martínez-Haya, Giel Berden, Jos Oomens
ChemPlusChem, January 11, 2012, DOI: 10.1002/cplu.201100044. Read article.

One-Step Decatungstate-Photomediated PEGylation of Single-Walled Carbon Nanotubes

2012-02-07T:+05:00

Off the wall: A straightforward PEGylation of single-walled carbon nanotubes (SWCNTs) has been performed by photomediated addition of various PEG derivatives onto the nanotube surfaces. The reaction was promoted both by UV and by solar light and took place under very mild conditions using commercial PEGs as PEGylating agents (see figure). Interestingly, the functionalization caused a partial dissolution of the resulting CNTs in the reaction medium.

[Full Paper]
Davide Ravelli, Sara Montanaro, Corrado Tomasi, Pietro Galinetto, Eliana Quartarone, Daniele Merli, Piercarlo Mustarelli, Maurizio Fagnoni
ChemPlusChem, February 7, 2012, DOI: 10.1002/cplu.201100040. Read article.

Surface Functionalization and Characterization of TiO₂ with Cibacron Blue Dye: An Affinity Column for Proteins

Chilukuri Subbalakshmi, Manaswita Nag, Sunkara V. Manorama — 2012-01-20T:+05:00

Get a load of this! The purification of lactic dehydrogenase (LHD) using an affinity column of TiO₂ functionalized with Cibacron blue dye is illustrated. The large capacity of the TiO₂–CB NP microtip column for proteins, its stability at room temperature, and low cost of preparation suggest that TiO₂–CB NPs are useful for rapid protein purification. The two-step procedure results in the recovery of over 90 % of the protein loaded.

[Full Paper]
Chilukuri Subbalakshmi, Manaswita Nag, Sunkara V. Manorama
ChemPlusChem, January 20, 2012, DOI: 10.1002/cplu.201100039. Read article.

A Molecular Lock and Key: “Unlocked–Locked” Conformational Switching of a Receptor by Anions

2012-01-04T:+05:00

Lock up your valuables: Receptor 1 acts as a “molecular lock” and anions act as “keys”; H₂PO₄⁻ can “lock” 1 by switching it from its “unlocked” conformation, however, the structurally similar HSO₄⁻ cannot “lock” receptor 1 as evidenced by single-crystal X-ray analysis (see scheme). The “unlocked–locked” conformational switching of 1 was investigated by monitoring changes in fluorescence intensity in the presence of different anions.

[Communication]
Sasanka Dalapati, Md. Akhtarul Alam, Sankar Jana, Rajat Saha, Saptarshi Biswas, Nikhil Guchhait
ChemPlusChem, January 4, 2012, DOI: 10.1002/cplu.201100036. Read article.

A Brief Summary of the Synthesis of Polyester Building-Block Chemicals and Biofuels from 5-Hydroxymethylfurfural

Saikat Dutta, Sudipta De, Basudeb Saha — 2012-02-02T:+05:00

Out of the woods: Considerable advances have been made for the synthesis of furan-based polyester building blocks, especially 2,5-furandicarboxylic acid (FDCA), by using nanoparticulate gold catalysts. This Minireview discuss the fundamental aspects of using nanoparticulate catalysts for the aerobic oxidation of biomass-derived 5-hydroxymethylfurfural (HMF) into FDCA and selective transformation of HMF into potential biofuels (DMF=2,5-dimethylfuran).

[Minireview]
Saikat Dutta, Sudipta De, Basudeb Saha
ChemPlusChem, February 2, 2012, DOI: 10.1002/cplu.201100035. Read article.

Palladium Nanoparticles Supported on Mixed-Linker Metal–Organic Frameworks as Highly Active Catalysts for Heck Reactions

2012-01-17T:+05:00

Like a MOF to a flame: A facile ion-exchange approach for the preparation of palladium nanoparticles (Pd NPs) catalysts supported on amine-functionalized, mixed-linker metal–organic frameworks based on MIL-53(Al) has been developed. These well-dispersed Pd NPs drastically enhance N₂ adsorption and show high activity and selectivity for Heck reactions (see scheme). The Pd NPs catalysts exhibit high stability and can be easily recovered and reused.

[Full Paper]
Yuanbiao Huang, Shuiying Gao, Tianfu Liu, Jian Lü, Xi Lin, Hongfang Li, Rong Cao
ChemPlusChem, January 17, 2012, DOI: 10.1002/cplu.201100021. Read article.

Fabrication of Soft Submicrospheres by Sequential Boronate Esterification and Their Dynamic Behavior

Ryuhei Nishiyabu, Shiori Teraoka, Yusuke Matsushima, Yuji Kubo — 2012-01-26T:+05:00

Pyridine-assisted sequential boronate esterification of benzene-1,4-diboronic acid and 1,2,4,5-tetrahydroxybenzene has led to hierarchically structured submicrospheres. The dynamic covalent functionality of the boronate ester linkage enables not only reversible formation by a pH switch but also morphological transformation of the submicrospheres by constitutional exchange reactions (see figure).

[Full Paper]
Ryuhei Nishiyabu, Shiori Teraoka, Yusuke Matsushima, Yuji Kubo
ChemPlusChem, January 26, 2012, DOI: 10.1002/cplu.201100008. Read article.

H₂O₂-Aided Seed-Mediated Synthesis of Silver Nanoplates with Improved Yield and Efficiency

Na Li, Qiao Zhang, Sean Quinlivan, James Goebl, Yang Gan, Yadong Yin — 2012-02-01T:+05:00

Nanoplates: Hydrogen peroxide is added in a seed-mediated growth process for producing silver nanoplates (see graphic) with not only significantly improved synthetic yield, but also greatly shortened reaction time and much enhanced reproducibility.

[Communication]
Na Li, Qiao Zhang, Sean Quinlivan, James Goebl, Yang Gan, Yadong Yin
ChemPhysChem, February 1, 2012, DOI: 10.1002/cphc.201101018. Read article.

Do Cation···π Interactions Always Need to be 1:1?

Sharon Achamma Abraham, Deepthi Jose, Ayan Datta — 2012-01-20T:+05:00

The more the better: Calculations and crystal-structure analyses show that a single electron-rich aromatic ring can simultaneously bind to two cations on its top and bottom π surfaces (see picture).

[Communication]
Sharon Achamma Abraham, Deepthi Jose, Ayan Datta
ChemPhysChem, January 20, 2012, DOI: 10.1002/cphc.201100996. Read article.

Reaction Pathways from Single-Molecule Trajectories

Haifeng Yuan, Michel Orrit — 2012-01-12T:+05:00

A good sign: Signal-pair histograms map transitions between different states of a single molecule (see picture) and open new opportunities for the reconstruction of kinetic pathways.

[Highlight]
Haifeng Yuan, Michel Orrit
ChemPhysChem, January 12, 2012, DOI: 10.1002/cphc.201100983. Read article.

Can Aromaticity Coexist with Diradical Character? An Ab Initio Valence Bond Study of S₂N₂ and Related 6π-Electron Four-Membered Rings E₂N₂ and E₄²⁺ (E=S, Se, Te)

Benoît Braïda, Aurélien Lo, Philippe C. Hiberty — 2012-01-24T:+05:00

Radical ideas about diradicals: A series of 6π-electron 4-center species, E₂N₂ and E₄²⁺ (E=S, Se, Te; see picture) is studied by means of ab initio valence bond methods. It is shown that aromaticity and diradical character do not exclude each other, contrary to what is usually claimed.

[Article]
Benoît Braïda, Aurélien Lo, Philippe C. Hiberty
ChemPhysChem, January 24, 2012, DOI: 10.1002/cphc.201100959. Read article.

Photoinduced Electron Transfer in Zinc Naphthalocyanine–Naphthalenediimide Supramolecular Dyads

Mohamed E. El-Khouly, Andrey G. Moiseev, Art van der Est, Shunichi Fukuzumi — 2012-01-31T:+05:00

Long live the dyads: Efficient electron transfer and relatively long-lived charge-separated states are achieved of light-harvesting zinc naphthalocyanine:naphthalenediimide supramolecular dyads utilizing the femtosecond transient absorption technique in toluene.

[Article]
Mohamed E. El-Khouly, Andrey G. Moiseev, Art van der Est, Shunichi Fukuzumi
ChemPhysChem, January 31, 2012, DOI: 10.1002/cphc.201100948. Read article.

Reaction Dynamics: Rules Change with Molecular Size

Markus Meuwly — 2012-01-17T:+05:00

Playing by the rules: A combined experimental/atomistic simulation approach is a powerful means to better understand chemical reactivity (see picture) and to best take advantage of mode-specific processes, highlighted herein.

[Highlight]
Markus Meuwly
ChemPhysChem, January 17, 2012, DOI: 10.1002/cphc.201100936. Read article.

Coherent Motion Reveals Non-Ergodic Nature of Internal Conversion between Excited States

Thomas S. Kuhlman, Theis I. Sølling, Klaus B. Møller — 2012-01-25T:+05:00

Inherently non-ergodic: The nature of a fundamental process such as internal conversion is inherently more complex than simple models might suggest. By following the vibrational dynamics during a transition between two electronic states, the complex nature can be disentangled and it is revealed how specific low-frequency modes play a significant role revealing the non-ergodic behavior (see picture).

[Article]
Thomas S. Kuhlman, Theis I. Sølling, Klaus B. Møller
ChemPhysChem, January 25, 2012, DOI: 10.1002/cphc.201100929. Read article.

Defining a Polymethine Dye for Fluorescence Anisotropy Applications in the Near-Infrared Spectral Range

Tiffany P. Gustafson, Qian Cao, Samuel Achilefu, Mikhail Y. Berezin — 2012-02-02T:+05:00

This dye does it! Fluorescence anisotropy in the near-infrared (NIR) spectral range is challenging because appropriate NIR fluorescent labels still need to be identified. Polymethine fluorescent dyes are evaluated for this purpose. The most promising label (LS601) is then utilized in conjugation reactions to demonstrate the feasibility of fluorescence anisotropy in the NIR range (see picture).

[Article]
Tiffany P. Gustafson, Qian Cao, Samuel Achilefu, Mikhail Y. Berezin
ChemPhysChem, February 2, 2012, DOI: 10.1002/cphc.201100916. Read article.

Electron Transfer and Switching in Rigid [2]Rotaxanes Adsorbed on TiO₂ Nanoparticles

Elena Lestini, Kirill Nikitin, Jacek K. Stolarczyk, Donald Fitzmaurice — 2012-01-27T:+05:00

Peeling back the layers: In contrast with findings in the solution phase, shuttling of the crown ether ring is inhibited in a rigid bistable [2]rotaxane when adsorbed on a TiO₂ nanoparticle (see picture). The results are analysed in terms of the donor–bridge–acceptor electron transfer formalism and presence of an electrical double layer.

[Article]
Elena Lestini, Kirill Nikitin, Jacek K. Stolarczyk, Donald Fitzmaurice
ChemPhysChem, January 27, 2012, DOI: 10.1002/cphc.201100903. Read article.

Removing Polyvinylpyrrolidone from Catalytic Pt Nanoparticles without Modification of Superficial Order

J. Monzó, M. T. M. Koper, P. Rodriguez — 2012-01-27T:+05:00

Clean catalysts: A facile and novel chemical method is introduced for cleaning Pt nanoparticles with preferential orientation. The method is based on the idea that the decomposition of hydrogen peroxide may aid in removing organic components from the Pt-nanoparticle surface, and does not introduce any major loss of superficial structure.

[Article]
J. Monzó, M. T. M. Koper, P. Rodriguez
ChemPhysChem, January 27, 2012, DOI: 10.1002/cphc.201100894. Read article.

Supramolecular Systems Based on Novel Mono- and Dicationic Pyrimidinic Amphiphiles and Oligonucleotides: A Self-Organization and Complexation Study

2012-01-27T:+05:00

Novel mono- and dicationic pyrimidinic surfactants are synthesized and their aggregation behavior is studied by methods of tensiometry and nuclear magnetic resonance self-diffusion. To estimate their potentiality as gene delivery agents, the complexation with oligonucleotides is explored (see picture).

[Article]
Lucia Zakharova, Mikhail Voronin, Vyacheslav Semenov, Dinar Gabdrakhmanov, Victor Syakaev, Yuri Gogolev, Rashit Giniyatullin, Svetlana Lukashenko, Vladimir Reznik, Shamil Latypov, Alexander Konovalov, Yuri Zuev
ChemPhysChem, January 27, 2012, DOI: 10.1002/cphc.201100888. Read article.

Structure–Property Relationships in Ionic Liquids: A Study of the Anion Dependence in Vaporization Enthalpies of Imidazolium-Based Ionic Liquids

2012-02-01T:+05:00

Depend or not depend: The quartz crystal microbalance and far-IR spectroscopy are used to determine vaporization enthalpies, Δ_l^gH°_m, for a series of ionic liquids (ILs) [C₂mim][X] (see picture). Dependences of vaporization enthalpies on physicochemical parameters specific for anions are revealed and a simple group-contribution method is developed for predicting vaporization enthalpies of alkyl imidazolium-based ILs.

[Article]
Dzmitry H. Zaitsau, Koichi Fumino, Vladimir N. Emel'yanenko, Andrei V. Yermalayeu, Ralf Ludwig , Sergey P. Verevkin
ChemPhysChem, February 1, 2012, DOI: 10.1002/cphc.201100879. Read article.

Coordination Environment of Highly Concentrated Solutions of Cu^II in Ionic Liquids through a Multidisciplinary Approach

2012-02-06T:+05:00

Counteranion complexation ability determines the nature of the complexes in concentrated solutions of Cu^II salts in imidazolium-based ionic liquids (ILs), whereas the salt/IL molar ratio plays only a marginal role, according to spectroscopic and electrochemical studies. DFT calculations suggest that [CuCl₃]⁻ and [CuCl₄]²⁻ are the dominant Cu^II species when the counteranion is Cl⁻ (see picture).

[Article]
Stefano Caporali, Cinzia Chiappe, Tiziana Ghilardi, Christian Silvio Pomelli, Calogero Pinzino
ChemPhysChem, February 6, 2012, DOI: 10.1002/cphc.201100876. Read article.

An in Situ STM and DTS Study of the Extremely Pure [EMIM]FAP/Au(111) Interface

Natalia Borisenko, Sherif Zein El Abedin, Frank Endres — 2011-12-30T:+05:00

Ionic liquid adlayers: An in situ STM study of extremely pure 1-ethyl-3-methylimidazolium tris(pentafluoroethyl)trifluorophosphate on Au(111) shows potential-dependent surface structures that can be ascribed to cation and/or anion adsorption.

[Article]
Natalia Borisenko, Sherif Zein El Abedin, Frank Endres
ChemPhysChem, December 30, 2011, DOI: 10.1002/cphc.201100873. Read article.

Determination of LFER Descriptors of 30 Cations of Ionic Liquids—Progress in Understanding Their Molecular Interaction Potentials

2012-01-27T:+05:00

Clarifying interactions: The LFER descriptors for the excess molar refractivity and the molar volume are calculated in silico and for hydrogen-bonding acidity and basicity, and the polarizability/dipolarity of ionic liquid cations are experimentally determined through high-performance liquid chromatography measurements. A parameter is successfully added to account for the charge of the ILs (see picture).

[Article]
Chul-Woong Cho, Christian Jungnickel, Stefan Stolte, Ulrich Preiss, Jürgen Arning, Johannes Ranke, Ingo Krossing, Jorg Thöming
ChemPhysChem, January 27, 2012, DOI: 10.1002/cphc.201100872. Read article.

Cation–π Interactions between a Free-Base Porphyrin and an Ionic Liquid: A Computational Study

Zhen Cao, Shu Li, Tianying Yan — 2012-01-17T:+05:00

Cation–π stacking: A free-base porphyrin (FBP) is sandwiched between two 1-butyl-3-methylimidazolium (BMIM⁺) cations with a slipped-parallel alignment in an ionic liquid, due to the cation–π interactions between the FBP and BMIM⁺.

[Article]
Zhen Cao, Shu Li, Tianying Yan
ChemPhysChem, January 17, 2012, DOI: 10.1002/cphc.201100868. Read article.

Role of Hydrocarbon Radicals CH_x (x=1, 2, 3) in Graphene Growth: A Theoretical Perspective

Chong Wang, Bo Xiao, Yi-hong Ding — 2012-01-31T:+05:00

Growing well: Many outstanding properties of graphene are blocked by the existence of structural defects (see picture). An important healing mechanism that takes place during the growth of this material via plasma-enhanced chemical vapor decomposition (PECVD) is proposed. The three-step process is based on the incorporation of C atoms from hydrocarbon radicals into the single-vacancy defects of graphene.

[Article]
Chong Wang, Bo Xiao, Yi-hong Ding
ChemPhysChem, January 31, 2012, DOI: 10.1002/cphc.201100864. Read article.

In Situ Observation of the Thermally Induced Growth of Platinum-Nanoparticle Catalysts Using High-Temperature X-ray Diffraction

Frédéric Hasché, Mehtap Oezaslan, Peter Strasser — 2012-01-27T:+05:00

Stable catalysts: The thermal durability of carbon-supported nanoparticles below 3 nm is examined using high-temperature X-ray diffraction. The effects of surface area, Pt loading, temperature, and gas environment on the particle growth are identified (see graph). The study provides a guideline for designing enhanced, long-term thermally stable nanoparticle catalysts.

[Article]
Frédéric Hasché, Mehtap Oezaslan, Peter Strasser
ChemPhysChem, January 27, 2012, DOI: 10.1002/cphc.201100857. Read article.

Further Insight into the Photostability of the Pyrene Fluorophore in Halogenated Solvents

2012-01-24T:+05:00

The use of dichloromethane can be an excellent alternative to chloroform when the good solubility properties of halogenated solvents are needed applying pyrene systems as fluorescent probes. The reason for this lies in the different reactivity of chloromethyl and dichloromethyl radicals towards pyrene and oxygen.

[Article]
Jordi Aguilera-Sigalat, Jaime Sanchez-SanMartín, Carlos E. Agudelo-Morales, Elena Zaballos, Raquel E. Galian, Julia Pérez-Prieto
ChemPhysChem, January 24, 2012, DOI: 10.1002/cphc.201100843. Read article.

Nanoconfinement Effects: Glucose Oxidase Reaction Kinetics in Nanofluidics

2012-02-06T:+05:00

Size-tunable nanofluidic devices coupled to an electrochemical detector are fabricated and used to study the reaction kinetics of glucose oxidase confined in nanochannels (see picture). Significant channel-size-dependent effects are observed, demonstrating the influence of spatial confinement on the enzyme reaction kinetics.

[Article]
Chen Wang, Zhen-Huan Sheng, Jun Ouyang, Jing-Juan Xu, Hong-Yuan Chen, Xing-Hua Xia
ChemPhysChem, February 6, 2012, DOI: 10.1002/cphc.201100842. Read article.

Ortho-Functionalized Perylenediimides for Highly Fluorescent Water-Soluble Dyes

2012-01-13T:+05:00

Clearly visible: A water-soluble and highly fluorescent perylenediimide is synthesized via ruthenium-catalyzed alkylation with outstanding yields (see scheme). For the first time, the possibility to use phosphonate derivatives in a Murai-type reaction is demonstrated.

[Communication]
Glauco Battagliarin, Melari Davies, Stephan Mackowiak, Chen Li, Klaus Müllen
ChemPhysChem, January 13, 2012, DOI: 10.1002/cphc.201100833. Read article.

Determination of Hydrogen-Bond-Accepting and –Donating Abilities of Ionic Liquids with Halogeno Complex Anions by Means of ¹H NMR Spectroscopy

Ralf Lungwitz, Stefan Spange — 2012-01-27T:+05:00

Two for the price of one: The imidazolium cation serves both as part of the ionic liquid (IL) and as an NMR probe. Hydrogen-bond-accepting (HBA) and donating (HBD) abilities of ILs with halogeno complex anions (X⁻) are determined by means of ¹H NMR spectroscopy (see picture). The chemical shift of the H(2) atom is a function of the HBA strength of the anion.

[Article]
Ralf Lungwitz, Stefan Spange
ChemPhysChem, January 27, 2012, DOI: 10.1002/cphc.201100832. Read article.

X-Ray Photoelectron Spectroscopy of Ferrocenyl- and Ferrocenium-Based Ionic Liquids

Alasdair W. Taylor, Peter Licence — 2012-01-27T:+05:00

Look sharp! X-ray photoelectron spectroscopy is used to study a series of five 1-(ferrocenylmethyl)-3-methylimidazolium- and 1-(ferroceniummethyl)-3-methylimidazolium-based salts (see picture). All samples emit good photoelectron fluxes with sharp, well-resolved photoelectron peaks.

[Article]
Alasdair W. Taylor, Peter Licence
ChemPhysChem, January 27, 2012, DOI: 10.1002/cphc.201100829. Read article.

Linking Single-Molecule Blinking to Chromophore Structure and Redox Potentials

2011-12-08T:+05:00

The missing link: Blinking of three dyes from a homologous series (Cy3, Cy5, Cy7) is studied (see picture). The underlying radical anion states are induced by controlling the oxygen concentration and by adding the reductant ascorbic acid. For different conditions the OFF-state lifetime always increases in the order Cy3

[Article]
Ingo H. Stein, Stella Capone, Jochem H. Smit, Fabian Baumann, Thorben Cordes, Philip Tinnefeld
ChemPhysChem, December 8, 2011, DOI: 10.1002/cphc.201100820. Read article.

Demonstration of Photoluminescence and Metal-Enhanced Fluorescence of Exfoliated MoS₂

Kangfu Zhou, Yihua Zhu, Xiaoling Yang, Jinghong Zhou, Chunzhong Li — 2012-01-13T:+05:00

Thinly spread: Ultrathin layers of exfoliated MoS₂ exhibit remarkable photoluminescence which is absence in bulk MoS₂. The intensity of the fluorescence is further enhanced by Ag@SiO₂ core/shell composites due to on metal-enhanced fluorescence (see picture).

[Communication]
Kangfu Zhou, Yihua Zhu, Xiaoling Yang, Jinghong Zhou, Chunzhong Li
ChemPhysChem, January 13, 2012, DOI: 10.1002/cphc.201100813. Read article.

NMR Investigation of Imidazolium-Based Ionic Liquids and Their Aqueous Mixtures

2012-01-20T:+05:00

Holding water: The interaction of water with the ionic liquids (ILs) 1-hexyl- and 1-octyl-3-methylimidazolium bromide, at IL concentrations above the critical aggregation concentration, is investigated by NMR spectroscopy (see figure). Water influences the environment close to the polar region of ILs at the lowest water content. Upon increasing the water fraction, the IL molecules form aggregates where contacts occur between the polar and apolar regions.

[Article]
Flaminia Cesare Marincola, Cristina Piras, Olga Russina, Lorenzo Gontrani, Giuseppe Saba, Adolfo Lai
ChemPhysChem, January 20, 2012, DOI: 10.1002/cphc.201100810. Read article.

Diffusive Shielding Stabilizes Bulk Nanobubble Clusters

Joost H. Weijs, James R. T. Seddon, Detlef Lohse — 2012-01-02T:+05:00

Small, but tough: Bulk nanobubble clusters can be stable under specific conditions. MD simulations (see picture) of binary mixtures of simple (Lennard-Jones) fluids are used to show this.

[Article]
Joost H. Weijs, James R. T. Seddon, Detlef Lohse
ChemPhysChem, January 2, 2012, DOI: 10.1002/cphc.201100807. Read article.

Water-Soluble Monodispersed Lanthanide Oxide Submicrospheres: PVP-Assisted Hydrothermal Synthesis, Size-Control and Luminescence Properties

2011-12-23T:+05:00

Easy! A facile hydrothermal synthetic route is presented to prepare a class of monodispersed lanthanide-based compound submicrospheres with controllable size (see picture). The method only employs raw lanthanide oxides as starting material, urea as precipitator and poly(N-vinyl-2-pyrrolidone) as surfactant.

[Article]
Ying Cui, Xiaoyong Lai, Li Li, Zhudong Hu, Shuo Wang, Jonathan E. Halpert, Ranbo Yu, Dan Wang
ChemPhysChem, December 23, 2011, DOI: 10.1002/cphc.201100806. Read article.

In Situ Formation of One-Dimensional Assemblies of Gold Nanoparticles in Confined Media

2012-01-27T:+05:00

Assemble! One dimensional Au nanoparticles arrays are created upon solvent drying onto a solid support by exploiting the aurophilic attraction between Au ions complexed to a coordinating ligand, such as oleylamine, and the subsequent formation of polymeric bundles (see picture).

[Article]
Jorge Carballido-Landeira, Sonia Goy-López, Alberto P. Muñuzuri, Pablo Taboada, Víctor Mosquera
ChemPhysChem, January 27, 2012, DOI: 10.1002/cphc.201100796. Read article.

Absorption, Luminescence, and Sizing of Organic Dye Nanoparticles and of Patterns Formed Upon Dewetting

Alexander Gaiduk, Mustafa Yorulmaz, Eléna Ishow, Michel Orrit — 2011-12-19T:+05:00

Labyrinthine: Quantitative insight into phototphysics of organic dye nanoparticles and the dewetting induced patterns formed from a push–pull triarylamine dye is obtained by using simultaneous absorption and fluorescence microscopy (see picture). The quantum yield of organic nanoparticles and the number of molecules forming the nanoparticles and patterns are deduced.

[Article]
Alexander Gaiduk, Mustafa Yorulmaz, Eléna Ishow, Michel Orrit
ChemPhysChem, December 19, 2011, DOI: 10.1002/cphc.201100788. Read article.

Probing the Electronic State of a Single Coronene Molecule by the Emission from Proximate Fluorophores

2012-01-17T:+05:00

Long time, no see: The long triplet state lifetime of hexa-peri-hexabenzocoronene (blue) appears as dark states in the emission of the perylenemonoimide periphery (green).

[Article]
Burkhard Fückel, Gerald Hinze, Jishan Wu, Klaus Müllen, Thomas Basché
ChemPhysChem, January 17, 2012, DOI: 10.1002/cphc.201100785. Read article.

Laser Control of Zeolite Nucleation

2012-01-20T:+05:00

Cut down to size: Presursor solutions for the synthesis of zeolites are irradiated by means of a Nd-YAG laser (see picture). Upon a hydrothermal treatment, the zeolite crystal size exponentially decreased as a function of laser irradiation time.

[Article]
Marta Navarro, Alvaro Mayoral, Ester Mateo, Ruth Lahoz, Germán F. de la Fuente, Joaquín Coronas
ChemPhysChem, January 20, 2012, DOI: 10.1002/cphc.201100783. Read article.

Photobleaching and Blinking of TAMRA Induced by Mn²⁺

Elana M. S. Stennett, Gerdenis Kodis, Marcia Levitus — 2012-02-01T:+05:00

Blinking and bleaching: Coordination of Mn²⁺ to DNA induces intersystem crossing, causing fluctuations in the fluorescence intensity and accelerated photobleaching.

[Communication]
Elana M. S. Stennett, Gerdenis Kodis, Marcia Levitus
ChemPhysChem, February 1, 2012, DOI: 10.1002/cphc.201100781. Read article.

Properties of Oligothiophene Dendrimers as a Function of Molecular Architecture and Generation Number

2012-01-27T:+05:00

All-thiophene dendrimers are investigated with regard to their molecular geometries and electronic structure by means of DFT and TD-DFT calculations, which are used to examine the dependence of properties such as the lowest π–π* transition energy ε_g on molecular dimensions (number of thiophene rings n) and symmetric versus unsymmetric architecture (fractions of α–α and α–β linkages χ_α–α and χ_α–β; see picture).

[Article]
Esther Córdova-Mateo , Francisco Rodríguez-Ropero, Oscar Bertran, Carlos Alemán
ChemPhysChem, January 27, 2012, DOI: 10.1002/cphc.201100780. Read article.

The Effect of Temperature on Single-Polypeptide Adsorption

Sandra Kienle, Susanne Liese, Nadine Schwierz, Roland R. Netz, Thorsten Hugel — 2012-01-31T:+05:00

Compensating Mechanisms: The temperature-dependent desorption of single polypeptides from hydrophobic surfaces, studied by means of atomic force microscopy and molecular dynamics simulations, shows a strong compensation mechanism between the different contributions to the desorption force. This is reminiscent of the protein-folding process, where large entropic and enthalpic contributions compensate each other, resulting in a small free-energy difference between the folded and unfolded states.

[Article]
Sandra Kienle, Susanne Liese, Nadine Schwierz, Roland R. Netz, Thorsten Hugel
ChemPhysChem, January 31, 2012, DOI: 10.1002/cphc.201100776. Read article.

Probing the Chemical Functionalization of Single-Walled Carbon Nanotubes with Multiple Carbon Ad-Dimer Defects

Dong-Lai Wang , Hong-Liang Xu, Zhong-Min Su, Shabbir Muhammad, Dong-Yan Hou — 2012-02-02T:+05:00

Drying-tube-shaped SWCNTs with multiple carbon ad-dimer defects, constructed by inserting C₂ units into armchair (n,n,m) single-walled carbon nanotubes (n=4–8) with m=7 and 13 C layers, and their hydrogenated, fluorinated, and chlorinated derivatives are investigated by DFT. Chemisorption of H, F, or Cl atoms on these SWCNTs is exothermic, and reaction energies E_r increase with increasing n (see picture).

[Article]
Dong-Lai Wang , Hong-Liang Xu, Zhong-Min Su, Shabbir Muhammad, Dong-Yan Hou
ChemPhysChem, February 2, 2012, DOI: 10.1002/cphc.201100774. Read article.

Electron Transport through Single π-Conjugated Molecules Bridging between Metal Electrodes

Manabu Kiguchi, Satoshi Kaneko — 2012-02-06T:+05:00

One and all: Electron transport through a single molecule between metal electrodes is a topic of great interest in the development of nanoscale molecular electronic devices. π-Conjugated molecules have attracted attention due to their unique properties. The fabrication and electron-transport properties of the single π-conjugated molecule junction (see picture) are discussed.

[Review]
Manabu Kiguchi, Satoshi Kaneko
ChemPhysChem, February 6, 2012, DOI: 10.1002/cphc.201100772. Read article.

Spectroscopic Properties of Gold Nanoparticles at the Single-Particle Level in Biological Environments

Laura C. Estrada, Enrico Gratton — 2012-02-01T:+05:00

Trap and track: The orbital tracking method (OTM) allows us to simultaneously track single nanoparticles (NPs) and spectroscopically characterize their emission while diffusing even inside cells. As the NPs are always trapped by the laser, a detail spectroscopic characterization of the NPs can be done, even if the NPs are moving in three dimensions and along microns (see picture).

[Article]
Laura C. Estrada, Enrico Gratton
ChemPhysChem, February 1, 2012, DOI: 10.1002/cphc.201100771. Read article.

Chromophores in Conjugated Polymers—All Straight?

John M. Lupton — 2011-12-16T:+05:00

What shape is it? Single-molecule and ensemble time-resolved studies support the notion that the π-bond in large macromolecules, such as conjugated polymers, is remarkably persistent in space: even individual chromophores can be bent and twisted, so that caution is warranted when interpreting a wide range of polarization-based spectroscopies.

[Concept]
John M. Lupton
ChemPhysChem, December 16, 2011, DOI: 10.1002/cphc.201100770. Read article.

Peptide–Antibody Complex as Handle for Single-Molecule Cut & Paste

2011-12-19T:+05:00

Molecule-by-molecule arrangement of proteins, for example, in enzymatic networks of predefined composition and proximity, is a major goal that may be accomplished by the single-molecule cut-and-paste technique (SMC&P). For this purpose, co-expressed anchors and handles as protein tags should be employed. As a first step in this direction, the authors develop an SMC&P design which exploits an antibody–peptide complex as a molecular handle.

[Communication]
Mathias Strackharn, Stefan W. Stahl, Philip M. D. Severin, Thomas Nicolaus, Hermann E. Gaub
ChemPhysChem, December 19, 2011, DOI: 10.1002/cphc.201100765. Read article.

Measurement and Applications of Long-Range Heteronuclear Scalar Couplings: Recent Experimental and Theoretical Developments

Nilamoni Nath, Lokesh, Nagarajarao Suryaprakash — 2012-02-02T:+05:00

Coupling at a distance: The advantages and limitations of a number of NMR techniques for the measurement of long-range heteronuclear couplings are discussed. The use of ⁿJ_XY couplings (see picture) in conjunction with theoretical calculations allows conclusions to be reached on the hyperconjugation, configurational analysis, and effect of the electronegativity of substituents.

[Minireview]
Nilamoni Nath, Lokesh, Nagarajarao Suryaprakash
ChemPhysChem, February 2, 2012, DOI: 10.1002/cphc.201100748. Read article.

Conjugation-Promoted Reaction of Open-Cage Fullerene: A Density Functional Theory Study

Yong Guo, Jingjing Yan, Niveen M. Khashab — 2012-01-20T:+05:00

Not that classical: The reaction of a carbonyl group on the fullerene orifice with triethyl phosphite most likely proceeds following the Abramov reaction to firstly form a classical product. However, this product is not stable and turns into an experimental product as the conversion transition state is stabilized by fullerene conjugation (see picture).

[Article]
Yong Guo, Jingjing Yan, Niveen M. Khashab
ChemPhysChem, January 20, 2012, DOI: 10.1002/cphc.201100745. Read article.

Mapping of Surface-Enhanced Fluorescence on Metal Nanoparticles using Super-Resolution Photoactivation Localization Microscopy

2011-12-19T:+05:00

Maps on metals: Photoactivation localization microscopy (PALM) is applied to study suface-enhanced fluorescence (SEF) on metal nanostructures (SEF-PALM), see picture. The detection of fluorescence from individual single molecules can be used to image the point-spread function and spatial distribution of the fluorescence emitted in the vicinity of a metal surface.

[Article]
Hongzhen Lin, Silvia P. Centeno, Liang Su, Bart Kenens, Susana Rocha, Michel Sliwa, Johan Hofkens, Hiroshi Uji-i
ChemPhysChem, December 19, 2011, DOI: 10.1002/cphc.201100743. Read article.

Organic–Organic Heterostructures: Concepts and Applications

Alexander Hinderhofer, Frank Schreiber — 2012-01-27T:+05:00

Less is more: Basic concepts, examples and applications of organic–organic heterostructures are reviewed (see picture). Heterostructures in the monolayer regime, including nanostructuring concepts and systems involving self-assembled monolayers, as well as various other architectures, including superlattices, are discussed.

[Review]
Alexander Hinderhofer, Frank Schreiber
ChemPhysChem, January 27, 2012, DOI: 10.1002/cphc.201100737. Read article.

The Surface Chemistry of Water on Fe(100): A Density Functional Theory Study

Ashriti Govender, Daniel Curulla Ferré, J. W. Niemantsverdriet — 2012-02-01T:+05:00

Holding water: In the formation of water by hydrogenation of atomic oxygen, the oxygen preferentially adsorbs at the four-fold hollow site, the hydroxyl group prefers the bridge site in a tilted configuration, and water is most stable when adsorbed at the top site with the two O-H bonds parallel to the Fe surface (see picture). Adsorption energies, optimised structures and vibrational frequencies of O, OH and H₂O for several adsorption modes are presented.

[Article]
Ashriti Govender, Daniel Curulla Ferré, J. W. Niemantsverdriet
ChemPhysChem, February 1, 2012, DOI: 10.1002/cphc.201100732. Read article.

Comparison of Low-Frequency Spectra between Aromatic and Nonaromatic Cation Based Ionic Liquids Using Femtosecond Raman-Induced Kerr Effect Spectroscopy

Hideaki Shirota — 2012-01-17T:+05:00

Bass notes: Low-frequency spectra below 200 cm⁻¹ of aromatic and nonaromatic cation based ionic liquids using femtosecond Raman-induced Kerr effect spectroscopy (see picture) are reviewed. The differences in the spectral line shape between two types of ionic liquids are discussed, and the relationships between the first moment of the broad spectral band and the bulk properties are compared.

[Minireview]
Hideaki Shirota
ChemPhysChem, January 17, 2012, DOI: 10.1002/cphc.201100731. Read article.

A Theoretical Investigation Into the 1,3-Dipolar Cycloaddition of Azidotrimethylsilane Onto Nanographene

Yanli Yuan, Peiyu Chen, Xingye Ren, Hongming Wang — 2012-02-03T:+05:00

Where to react?: Calculations reveal that the 1,3-dipolar cycloaddition of azidotrimethylsilane onto nanographene (NG) occurs through a two-step reaction mechanism. The reactivity of NG is discussed in detail, revealing that it is the electron density at the functionalization site (see picture) which dominates the reactivity rather than the energetic effect. As a result, the edge area is calculated to be much more reactive than the centre.

[Article]
Yanli Yuan, Peiyu Chen, Xingye Ren, Hongming Wang
ChemPhysChem, February 3, 2012, DOI: 10.1002/cphc.201100730. Read article.

Instantaneous Normal Mode Analysis of a Series of Model Molten Salts

Hualin Li, Mark N. Kobrak — 2012-01-12T:+05:00

Dynamics of a fused salt were previously shown to be affected by the mass and charge distributions of its component ions. These studies are now extended by using instantaneous normal mode analysis to explore how changes in ionic structure affect translational and rotational dynamics in a series of model salts, in which the charge distribution is modified by the addition of dummy atoms.

[Article]
Hualin Li, Mark N. Kobrak
ChemPhysChem, January 12, 2012, DOI: 10.1002/cphc.201100727. Read article.

Solute-Induced Microstructural Transition from Weak Aggregates towards a Curved Film of Surface-Active Extractants

Philippe Guilbaud, Thomas Zemb — 2012-01-17T:+05:00

Reverse micelles? The transition from weak aggregation to water-poor reverse micelles triggered by the presence of extracted ion pairs is modeled using molecular dynamics simulations (see picture). The presence of the ion induces a polar/apolar segregation and the formation of a curved film microstructure consistent with the classical inverse micelle.

[Communication]
Philippe Guilbaud, Thomas Zemb
ChemPhysChem, January 17, 2012, DOI: 10.1002/cphc.201100721. Read article.

Bayesian-Inference-Based Fluorescence Correlation Spectroscopy and Single-Molecule Burst Analysis Reveal the Influence of Dye Selection on DNA Hairpin Dynamics

Wolfgang Kügel, Adam Muschielok, Jens Michaelis — 2012-01-25T:+05:00

Dynamic studies: Fluorescence correlation spectroscopy (FCS) data are globally analyzed using the Bayesian inference. This approach is applied, in combination with the results from single-molecule burst analysis, to investigate the influence of various labels on DNA hairpin kinetics as a function of the salt concentration.

[Article]
Wolfgang Kügel, Adam Muschielok, Jens Michaelis
ChemPhysChem, January 25, 2012, DOI: 10.1002/cphc.201100720. Read article.

Effect of Ionic Liquid on Diffusion in P123 Gel: Fluorescence Correlation Spectroscopy

Amit Kumar Mandal, Supratik Sen Mojumdar, Atanu Kumar Das, Kankan Bhattacharyya — 2012-01-05T:+05:00

Fluorescent subterfuge: The effect of two room-temperature ionic liquids (RTILs) on the diffusion of three fluorescent dyes in the gel phase of a triblock copolymer (see picture) was studied by using fluorescence correlation spectroscopy. It is shown that the RTIL affects the structure of the gel by modifying the size of the micellar aggregates and by penetrating the core.

[Article]
Amit Kumar Mandal, Supratik Sen Mojumdar, Atanu Kumar Das, Kankan Bhattacharyya
ChemPhysChem, January 5, 2012, DOI: 10.1002/cphc.201100717. Read article.

Effect of Surface Hydrophobicity on the Formation and Stability of Oxygen Nanobubbles

Gang Pan, Bo Yang — 2012-01-24T:+05:00

The formation mechanism of a nanoscale gas state is studied on modified inorganic clay surfaces (see picture). The results suggest that a nanoscale gas state can be formed on both hydrophobic and hydrophilic particle surfaces, but that the stability of the surface nanoscale gas state can vary greatly depending on the hydrophobicity of the solid surfaces.

[Article]
Gang Pan, Bo Yang
ChemPhysChem, January 24, 2012, DOI: 10.1002/cphc.201100714. Read article.

Formation Principles and Ligand Dynamics of Nanoassemblies of CdSe Quantum Dots and Functionalised Dye Molecules

2011-12-23T:+05:00

Quenching the glow! The size-dependent photoluminescence quenching of semiconductor quantum dots by functionalised dye molecules in solution is analysed with respect to Förster resonance energy transfer (FRET) and non-FRET contributions (see picture). By this approach, assembly formation and ligand dynamics can be studied at extremely low concentrations of quantum dots and dye molecules.

[Article]
Thomas Blaudeck, Eduard I. Zenkevich, Mohamed Abdel-Mottaleb, Klementyna Szwaykowska, Danny Kowerko, Frank Cichos, Christian von Borczyskowski
ChemPhysChem, December 23, 2011, DOI: 10.1002/cphc.201100711. Read article.

β-Fragmentation of Tertiary Alkoxyl Radicals: G3(MP2)-RAD and Natural Bond Orbital Investigations

Sylvain R. A. Marque, Didier Siri — 2012-01-30T:+05:00

Amazing lone pair effect: G3 (MP2)-RAD investigations combined with DFT calculations and NBO analysis shows that the β-fragmentation of tertiary alkoxyl radicals R₁R₂YCO^. (see picture) shows a banana bond at the TS (np,O→β-LUMO) when Y bears a lone pair, in sharp contrast with the σ*_C-C→β-LUMO interaction for the conventional homolytic C-Y bond cleavage.

[Communication]
Sylvain R. A. Marque, Didier Siri
ChemPhysChem, January 30, 2012, DOI: 10.1002/cphc.201100708. Read article.

Three-Dimensional Super-Resolution Imaging of the Midplane Protein FtsZ in Live Caulobacter crescentus Cells Using Astigmatism

Julie S. Biteen, Erin D. Goley, Lucy Shapiro, W. E. Moerner — 2012-01-20T:+05:00

3D is here to stay: Three-dimensional super-resolution astigmatic optical imaging provides images of the FtsZ Z-ring in bacterial cells in various stages of the cell cycle. The picture shows, left to right: live stalked cell, live pre-divisional cell, fixed stalked cell, fixed pre-divisional cell. Scale bar: 200 nm.

[Article]
Julie S. Biteen, Erin D. Goley, Lucy Shapiro, W. E. Moerner
ChemPhysChem, January 20, 2012, DOI: 10.1002/cphc.201100686. Read article.

Classical Reactive Molecular Dynamics Implementations: State of the Art

Karim Farah, Florian Müller-Plathe, Michael C. Böhm — 2012-01-27T:+05:00

Reactive molecular dynamics (RMD) simulations are used to investigate the time evolution, governed by empirical potential energy functions, of reactive systems (see graphic). RMD approaches are the only methods that allow the study of chemical reactions in large condensed-phase systems. Exciting microscopic insights into chemical reactions in condensed phases are discussed in this review.

[Minireview]
Karim Farah, Florian Müller-Plathe, Michael C. Böhm
ChemPhysChem, January 27, 2012, DOI: 10.1002/cphc.201100681. Read article.

Lipid Diffusion within Black Lipid Membranes Measured with Dual-Focus Fluorescence Correlation Spectroscopy

Kerstin Weiß, Jörg Enderlein — 2012-01-17T:+05:00

Watch them glow: A description and theoretical evaluation of dual-focus fluorescence correlation spectroscopy as a tool for measuring diffusion within lipid bilayers is presented (see picture). The method is applied to a study of the dependence of lipid diffusion on lipid and buffer composition with regard to the ionic strength of the buffer, particularly concerning the influence of mono- and divalent ions.

[Article]
Kerstin Weiß, Jörg Enderlein
ChemPhysChem, January 17, 2012, DOI: 10.1002/cphc.201100680. Read article.

Breathing Particles for Controlling Thermo-Sequential On/Off Drug Delivery

Anne-Claire Le Meur, Cyril Aymonier, Valérie Héroguez — 2012-01-24T:+05:00

Two for three: An original combination of two thermoresponsive polymers organized inside a single submicron particle is developed to release drug following a three-step process, which consists of a first spontaneous release at room temperature followed by two possible thermosensitive effects.

[Communication]
Anne-Claire Le Meur, Cyril Aymonier, Valérie Héroguez
ChemPhysChem, January 24, 2012, DOI: 10.1002/cphc.201100677. Read article.

Comprehensive Photophysical Behaviour of Ethynyl Fluorenes and Ethynyl Anthracenes Investigated by Fast and Ultrafast Time-Resolved Spectroscopy

2012-01-27T:+05:00

State secrets: The photophysical behaviour of ethynyl fluorenes and ethynyl anthracenes is modulated by the molecular structure and solvent polarity. The rate constants of the decay channels are modified by the relative energies of the optical singlet state (¹LE*), the charge-transfer singlet state (¹CT*), and an upper triplet of n,π* nature (see picture).

[Article]
Benedetta Carlotti, Rebecca Flamini, Anna Spalletti, Assunta Marrocchi, Fausto Elisei
ChemPhysChem, January 27, 2012, DOI: 10.1002/cphc.201100674. Read article.

Optical Modulation and Selective Recovery of Cy5 Fluorescence

Chaoyang Fan, Jung-Cheng Hsiang, Robert M. Dickson — 2011-11-15T:+05:00

Photoinduced isomerization of Cy5 from trans to cis can be quickly reversed with long-wavelength secondary illumination. Modulating this co-illumination directly encodes the modulation waveform on the higher energy Cy5 fluorescence, enabling its selective recovery even in the presence of overwhelming background. This low-energy, reversible, long-lived dark state makes Cy5 an excellent dye for synchronously amplified fluorescence image recovery (SAFIRe).

[Article]
Chaoyang Fan, Jung-Cheng Hsiang, Robert M. Dickson
ChemPhysChem, November 15, 2011, DOI: 10.1002/cphc.201100671. Read article.

Tip-Enhanced Near-Field Optical Microscopy of Quasi-1 D Nanostructures

Miriam Böhmler, Achim Hartschuh — 2011-12-08T:+05:00

High-resolution imaging and spectroscopy of single CdSe nanowires and carbon nanotubes using tip-enhanced near-field optical microscopy increases the optical excitation and emission rates within a nanoscale sample volume. The resulting signal enhancement for Raman scattering and photoluminescence as well as the tip–sample-distance dependence are investigated.

[Communication]
Miriam Böhmler, Achim Hartschuh
ChemPhysChem, December 8, 2011, DOI: 10.1002/cphc.201100670. Read article.

Long-Range Transport of Giant Vesicles along Microtubule Networks

Christoph Herold, Cécile Leduc, Robert Stock, Stefan Diez, Petra Schwille — 2011-12-23T:+05:00

Moving giant vesicles: In a biomimetic assay, giant unilamellar vesicles with membrane-anchored kinesin-1 motor proteins are transported along a two-dimensional microtubule network (see picture). In this assay, cooperatively acting motor proteins enable long traveling distances up to the millimeter range.

[Article]
Christoph Herold, Cécile Leduc, Robert Stock, Stefan Diez, Petra Schwille
ChemPhysChem, December 23, 2011, DOI: 10.1002/cphc.201100669. Read article.

What Determines the Rate of Excited-State Intramolecular Electron-Transfer Reaction of 4-(N,N'-dimethylamino)benzonitrile in Room Temperature Ionic Liquids? A Study in [bmim][PF₆]

Kotni Santhosh, Anunay Samanta — 2012-01-13T:+05:00

Electron transfer faster than solvation: The rate of excited-state intramolecular electron-transfer reaction of DMABN in [bmim][PF₆] is not determined by the dynamics of solvation.

[Article]
Kotni Santhosh, Anunay Samanta
ChemPhysChem, January 13, 2012, DOI: 10.1002/cphc.201100655. Read article.

Influence of the Number of Anchoring Groups on the Electronic and Mechanical Properties of Benzene-, Anthracene- and Pentacene-Based Molecular Devices

2012-01-24T:+05:00

Better connections: Calculations show that increasing the number of anchoring groups in model acenes leads to higher conductivity as well as mechanical and current stability (see picture; C gray, H white, S yellow) in molecule–Au electrode contacts. The results have implications for stochastic on/off switching (blinking), which is a major problem of single-molecule electronic devices.

[Article]
Ana Martín-Lasanta, Delia Miguel, Trinidad García, Juan A. López-Villanueva, Salvador Rodríguez-Bolívar, Francisco M. Gómez-Campos, Elena Buñuel, Diego J. Cárdenas, Luis Alvarez de Cienfuegos, Juan M. Cuerva
ChemPhysChem, January 24, 2012, DOI: 10.1002/cphc.201100582. Read article.

Isomerisation of CF₂ClCH₂Cl and CFCl₂CH₂F by Interchange of Cl and F Atoms with Analysis of the Unimolecular Reactions of Both Molecules

2012-01-27T:+05:00

Shall we switch partners? The F–Cl interchange reaction is an important unimolecular pathway for some hydrochlorofluorocarbons as illustrated by an experimental and computational investigation for the CH₂ClCF₂Cl–CH₂FCFCl₂ pair (see picture).

[Article]
Sarah A. Solaka, Sara E. Boshamer, Caroline L. Parworth, George L. Heard, D. W. Setser, Bert E. Holmes
ChemPhysChem, January 27, 2012, DOI: 10.1002/cphc.201100568. Read article.

Electron Correlation in Real Time

Giuseppe Sansone, Thomas Pfeifer, Konstantinos Simeonidis, Alexander I. Kuleff — 2011-12-08T:+05:00

Ultrafast electron dynamics: Electron correlation plays a key role in the relaxation mechanisms that characterize excited states of neutral or ionized atoms and molecules obtained by absorption of extreme ultraviolet (XUV) or X-ray radiation. The possibilities offered by femtosecond and attosecond XUV pulses (see picture) to investigate how electron correlations can influence and drive multielectron dynamics in atoms and molecules are presented.

[Minireview]
Giuseppe Sansone, Thomas Pfeifer, Konstantinos Simeonidis, Alexander I. Kuleff
ChemPhysChem, December 8, 2011, DOI: 10.1002/cphc.201100528. Read article.

Effect of an Ionic liquid on the Unfolding of Human Serum Albumin: A Fluorescence Correlation Spectroscopy Study

2011-09-16T:+05:00

Fluorescence fluctuations: The effect of a room temperature ionic liquid (RTIL) on the unfolding of human serum albumin (HSA) is studied by fluorescence correlation spectroscopy (see picture). The use of a denaturant (GdnHCl) in the presence of the RTIL causes significant changes in the structure and the time constants of the conformational fluctuations.

[Article]
Dibyendu Kumar Das, Atanu Kumar Das, Amit Kumar Mandal, Tridib Mondal, Kankan Bhattacharyya
ChemPhysChem, September 16, 2011, DOI: 10.1002/cphc.201100421. Read article.

HIV-1 Integrase: Mechanism and Inhibitor Design Edited by Nouri Neamati.

Maurizio Botta — 2012-02-06T:+05:00

John Wiley & Sons, Hoboken 2011. 384 pp., hardcover $ 119.99.—ISBN 978-0-47018-474-5

[Book Review]
Maurizio Botta
ChemMedChem, February 6, 2012, DOI: 10.1002/cmdc.201200047. Read article.

Drug Metabolism and Pharmacokinetics Quick Guide By Siamak C. Khojasteh, Harvey Wong and Cornelis E. C. A. Hop.

Andy Davis — 2012-01-27T:+05:00

Springer, Heidelberg 2011. xii+214 pp., softcover €42.75.—ISBN 978-1-4419-5628-6

[Book Review]
Andy Davis
ChemMedChem, January 27, 2012, DOI: 10.1002/cmdc.201200027. Read article.

Discovery of [(2R,5R)-5-{[(5-Fluoropyridin-2-yl)oxy]methyl}-2-methylpiperidin-1-yl][5-methyl-2-(pyrimidin-2-yl)phenyl]methanone (MK-6096): A Dual Orexin Receptor Antagonist with Potent Sleep-Promoting Properties

2012-02-03T:+05:00

Exploring DORAs: Orexin receptor antagonism has been identified as a new mechanism for treating insomnia with clinical proof of concept. The design of MK-6096 was partly driven by understanding the conformational properties anticipated to be favorable for high orexin receptor activity. MK-6096 represents a novel therapy for treating insomnia and other disorders related to sleep/wake dysregulation.

[Full Paper]
Paul J. Coleman, John D. Schreier, Christopher D. Cox, Michael J. Breslin, David B. Whitman, Michael J. Bogusky, Georgia B. McGaughey, Rodney A. Bednar, Wei Lemaire, Scott M. Doran, Steven V. Fox, Susan L. Garson, Anthony L. Gotter, C. Meacham Harrell, Duane R. Reiss, Tamara D. Cabalu, Donghui Cui, Thomayant Prueksaritanont, Joanne Stevens, Pamela L. Tannenbaum, Richard G. Ball, Joyce Stellabott, Steven D. Young, George D. Hartman, Christopher J. Winrow, John J. Renger
ChemMedChem, February 3, 2012, DOI: 10.1002/cmdc.201200025. Read article.

Chiral Drugs: Chemistry and Biological Action Edited by Guo-Qiang Lin, Qi-Dong You and Jie-Fei Cheng.

Thorleif Anthonsen — 2012-02-01T:+05:00

John Wiley & Sons, Hoboken 2011. 472 pp., hardcover $ 149.95.—ISBN 978-0-470-58720-1

[Book Review]
Thorleif Anthonsen
ChemMedChem, February 1, 2012, DOI: 10.1002/cmdc.201200019. Read article.

Sulfonimidamides as Sulfonamides Bioisosteres: Rational Evaluation through Synthetic, in Vitro, and in Vivo Studies with γ-Secretase Inhibitors

2012-02-03T:+05:00

The proof of the pudding: A proof-of-concept study using γ-secretase inhibitors as a model has shown that sulfonimidamides act as bioisosteres for sulfonamides. Detailed in vitro and in vivo profiling reveal that the sulfonimidamide motif imparts desirable properties such as decreased lipophilicity and plasma protein binding, accompanied by increased solubility. Our data support a wider use of this unique functional group in the design of new pharmacologically active agents.

[Communication]
Fernando Sehgelmeble, Juliette Janson, Colin Ray, Susanne Rosqvist, Susanne Gustavsson, Linda I. Nilsson, Alexander Minidis, Jörg Holenz, Didier Rotticci, Johan Lundkvist, Per I. Arvidsson
ChemMedChem, February 3, 2012, DOI: 10.1002/cmdc.201200014. Read article.

Synthesis and Evaluation of 1-Amino-6-halo-β-carbolines as Antimalarial and Antiprion Agents

2012-01-24T:+05:00

Parasites and problem proteins! Malaria and Creutzfeldt–Jakob disease (CJD), two very different conditions, may have a common therapeutic agent class in the 6-halo-β-carbolines. Synthesis of a compound library and screening against two strains of Plasmodium falciparum and in an in vitro model of prion disease revealed these agents as potential candidates for further development as both antiprion and antimalarial drugs.

[Full Paper]
Mark J. Thompson, Jennifer C. Louth, Susan M. Little, Matthew P. Jackson, Yohan Boursereau, Beining Chen, Iain Coldham
ChemMedChem, January 24, 2012, DOI: 10.1002/cmdc.201200002. Read article.

A 2,6-Disubstituted 4-Anilinoquinazoline Derivative Facilitates Cardiomyogenesis of Embryonic Stem Cells

2012-02-02T:+05:00

Cardiomyogenic agents: We explored the effects of EGFR inhibitors on cardiomyogenesis of embryonic stem (ES) cells and screened a quinazoline compound library for cardiomyogenic stimulators. Compound 62, a 2,6-disubstituted 4-anilinoquinazoline derivative, was found to be a potent cardiomyogenic inducer of ES cells with a mechanism distinct from that of iressa.

[Full Paper]
Guofang Shen, Ying Hu, Jianwei Wu, Ke Jin, Danyan Zhu, Yandong Zhang, Yongping Yu, Yijia Lou
ChemMedChem, February 2, 2012, DOI: 10.1002/cmdc.201100603. Read article.

Cytotoxic Salan–Titanium(IV) Complexes: High Activity Toward a Range of Sensitive and Drug-Resistant Cell Lines, and Mechanistic Insights

Cesar M. Manna, Ori Braitbard, Esther Weiss, Jacob Hochman, Edit Y. Tshuva — 2012-01-20T:+05:00

Titanic strength: Salan–Ti^IV complexes demonstrate high cytotoxicity toward a wide range of cancer cell lines, including cisplatin- and multi-drug-resistant lines, with marked selectivity for tumor tissue. These complexes are also highly robust; they retain activity after long-term pre-incubation in cell culture medium, and appear to induce p53-mediated cell-cycle arrest.

[Full Paper]
Cesar M. Manna, Ori Braitbard, Esther Weiss, Jacob Hochman, Edit Y. Tshuva
ChemMedChem, January 20, 2012, DOI: 10.1002/cmdc.201100593. Read article.

Dual Dehydrosqualene/Squalene Synthase Inhibitors: Leads for Innate Immune System-Based Therapeutics

2012-01-30T:+05:00

Double whammy! Small molecules that inhibit Staphylococcus aureus dehydrosqualene synthase (CrtM) or host squalene synthase (SQS) are of interest as novel, innate immunity-based therapeutics, blocking virulence or stimulating antibacterial neutrophil extracellular trap (NET) formation. The discovery of leads that do both represents a new route to treating staph infections.

[Communication]
Fu-Yang Lin, Yonghui Zhang, Mary Hensler, Yi-Liang Liu, Ohn A. Chow, Wei Zhu, Ke Wang, Ran Pang, Wdee Thienphrapa, Victor Nizet, Eric Oldfield
ChemMedChem, January 30, 2012, DOI: 10.1002/cmdc.201100589. Read article.

Preliminary Study of the Anticancer Applications of Mesoporous Materials Functionalized with the Natural Product Betulinic Acid

2012-01-25T:+05:00

The perfect combination: The combination of functionalized mesoporous materials such as MCM-41 with betulinic acid, a potent anticancer drug, led to novel drug delivery systems which may be useful in the future as adjuvant agents to avoid the recurrence of bone tumors on local implantations.

[Full Paper]
Sergio Sánchez-Muñoz, Santiago Gómez-Ruiz, Damián Pérez-Quintanilla, Sonia Morante-Zarcero, Isabel Sierra, Sanjiv Prashar, Reinhard Paschke, Goran N. Kaluđerović
ChemMedChem, January 25, 2012, DOI: 10.1002/cmdc.201100588. Read article.

Pyrazinamide: A Frontline Drug Used for Tuberculosis. Molecular Mechanism of Action Resolved after 50 Years?

Alvin S. Kalinda, Courtney C. Aldrich — 2012-01-13T:+05:00

Target acquired! After 50 years of use, has the molecular mode of action finally been identified for pyrazinamide? Recently, inhibition of trans-translation in Mycobacterium tuberculosis was suggested as a novel mode of action for this important TB drug. The results of the study by Zhang et al., reported in Science, are highlighted here.

[Highlight]
Alvin S. Kalinda, Courtney C. Aldrich
ChemMedChem, January 13, 2012, DOI: 10.1002/cmdc.201100587. Read article.

A Two-Step Strategy for Structure–Activity Relationship Studies of N-Methylated Aβ42 C-Terminal Fragments as Aβ42 Toxicity Inhibitors

Huiyuan Li, Reeve Zemel, Dahabada H. J. Lopes, Bernhard H. Monien, Gal Bitan — 2012-02-03T:+05:00

Step by Step: A two-step N-methyl amino acid substitution method was used for a structure–activity relationship (SAR) study of Aβ(31-42). This strategy provides a basis for the design of new peptidomimetic inhibitors with improved activity, physicochemical properties and metabolic stability.

[Full Paper]
Huiyuan Li, Reeve Zemel, Dahabada H. J. Lopes, Bernhard H. Monien, Gal Bitan
ChemMedChem, February 3, 2012, DOI: 10.1002/cmdc.201100584. Read article.

In Silico Identification of an Interferon Inhibitor

Markus Kaiser, Christian Ottmann — 2012-01-20T:+05:00

Inhibition of IFNα–IFNR: Interferon (IFN) is an important signaling molecule and antiviral therapeutic agent. However, in certain diseases like type I diabetes, IFN action can be harmful. Schneider and co-workers recently reported the identification of the first IFNα–IFNR inhibitor via in silico screening, which binds to IFNα and impedes interferon signaling in cells.

[Highlight]
Markus Kaiser, Christian Ottmann
ChemMedChem, January 20, 2012, DOI: 10.1002/cmdc.201100579. Read article.

Structure–Activity Relationships for Negative Allosteric mGluR5 Modulators

2012-01-20T:+05:00

Exploring a dimeric approach: The design and synthesis of 2-methyl-6-(phenylethynyl)pyridine (MPEP) analogues led to a potent and selective negative modulator of mGluR5. Compounds were characterized at mGluRs and iGluRs; binding and selectivity modes were investigated by homology modeling and docking studies.

[Full Paper]
Birgitte H. Kaae, Kasper Harpsøe, Trine Kvist, Jesper M. Mathiesen, Christina Mølck, David Gloriam, Hermogenes N. Jimenez, Michelle A. Uberti, Søren M. Nielsen, Birgitte Nielsen, Hans Bräuner-Osborne, Per Sauerberg, Rasmus P. Clausen, Ulf Madsen
ChemMedChem, January 20, 2012, DOI: 10.1002/cmdc.201100578. Read article.

Chromenopyrazoles: Non-psychoactive and Selective CB₁ Cannabinoid Agonists with Peripheral Antinociceptive Properties

2012-02-02T:+05:00

Peripheral cannabinoid: Chromenopyrazoles were identified as cannabinoid receptor ligands, and some compounds in the series were found to be selective agonists of the CB₁ receptor. Results of molecular modeling studies support this finding. Behavioral tests and peripheral pain assays carried out with the most effective agonist show peripheral analgesia without CNS-mediated effects.

[Full Paper]
Jose Cumella, Laura Hernández-Folgado, Rocio Girón, Eva Sánchez, Paula Morales, Dow P. Hurst, Maria Gómez-Cañas, Maria Gómez-Ruiz, Diana C. G. A. Pinto, Pilar Goya, Patricia H. Reggio, María Isabel Martin, Javier Fernández-Ruiz, Artur M. S. Silva, Nadine Jagerovic
ChemMedChem, February 2, 2012, DOI: 10.1002/cmdc.201100568. Read article.

Fluorogenic Peptide-Based Substrates for Monitoring Thrombin Activity

2012-01-31T:+05:00

An eye on thrombin: A series of fluorogenic peptidyl-AMC substrates were synthesized and subjected to a biological evaluation to determine their suitability in the thrombin generation test (TGT). Evaluation of the acquired thrombin generation curves showed that several of these substrates have excellent potential for replacement of the substrate in current use.

[Full Paper]
Sander S. van Berkel, Bas van der Lee, Floris L. van Delft, Rob Wagenvoord, H. Coenraad Hemker, Floris P. J. T. Rutjes
ChemMedChem, January 31, 2012, DOI: 10.1002/cmdc.201100560. Read article.

Polycyclic Cage Structures as Lipophilic Scaffolds for Neuroactive Drugs

2012-02-03T:+05:00

Scaffolds for neuroprotection: Less than five per cent of small-molecule drugs are able to cross the blood–brain barrier (BBB). Developments in the design of compounds incorporating lipophilic, polycyclic structures have been under intense investigation in recent years. Conjugation of privileged moieties and known drug structures to these polycyclic structures has enhanced the delivery of neuroactive drugs across the BBB with subsequent neuroprotective and/or neurorestorative activity.

[Minireview]
Jacques Joubert, Werner J. Geldenhuys, Cornelis J. Van der Schyf, Douglas W. Oliver, Hendrik Gert Kruger, Thavendran Govender, Sarel F. Malan
ChemMedChem, February 3, 2012, DOI: 10.1002/cmdc.201100559. Read article.

Investigation of D₁ Receptor–Agonist Interactions and D₁/D₂ Agonist Selectivity Using a Combination of Pharmacophore and Receptor Homology Modeling

Marcus Malo, Lars Brive, Kristina Luthman, Peder Svensson — 2012-02-07T:+05:00

The delicate balance between dopamine D₁ and D₂ agonism was investigated by using our combined receptor and pharmacophore modeling approach described in the preceding paper. Not only can the developed receptor models be used to understand the factors that determine receptor isoform selectivity, but also to design new dopamine receptor-selective agonists for use as potential therapeutic agents.

[Full Paper]
Marcus Malo, Lars Brive, Kristina Luthman, Peder Svensson
ChemMedChem, February 7, 2012, DOI: 10.1002/cmdc.201100546. Read article.

Investigation of D₂ Receptor–Agonist Interactions Using a Combination of Pharmacophore and Receptor Homology Modeling

Marcus Malo, Lars Brive, Kristina Luthman, Peder Svensson — 2012-02-07T:+05:00

The magic key for dopamine D₂ receptor agonism was studied by using a combined receptor and pharmacophore modeling approach. All available experimental data, including a set of carefully selected active and inactive ligands, were used to identify the reasons behind selectivity and to pinpoint the specific ligand–receptor interactions made by D₂ agonists.

[Full Paper]
Marcus Malo, Lars Brive, Kristina Luthman, Peder Svensson
ChemMedChem, February 7, 2012, DOI: 10.1002/cmdc.201100545. Read article.

8-Substituted 3-Arylcoumarins as Potent and Selective MAO-B Inhibitors: Synthesis, Pharmacological Evaluation, and Docking Studies

2012-01-27T:+05:00

B-selective! With the aim of finding new selective MAO-B inhibitors, herein we report the synthesis, in vitro evaluation, and a docking simulation of a new series of 3-arylcoumarins variously substituted at the 8-position as potential inhibitors of hMAO-A and B. Most of the studied compounds have high affinity and selectivity for hMAO-B, with IC₅₀ values in the low micro- to nanomolar range.

[Full Paper]
Dolores Viña, Maria J. Matos, Giulio Ferino, Enzo Cadoni, Reyes Laguna, Fernanda Borges, Eugenio Uriarte, Lourdes Santana
ChemMedChem, January 27, 2012, DOI: 10.1002/cmdc.201100538. Read article.

Arylpiperazine Dopamineric Ligands Protect Neuroblastoma Cells from Nitric Oxide (NO)-Induced Mitochondrial Damage and Apoptosis

2012-02-01T:+05:00

Guarding the grey matter! Arylpiperazine dopaminergic ligands protect neurons from nitric oxide cytotoxicity. Their ability to modulate cell survival signaling pathways, stabilize mitochondrial membrane, and ultimately prevent neuronal apoptosis, makes them plausible candidates for treatment of neurodegenerative diseases.

[Full Paper]
Gordana Tovilovic, Nevena Zogovic, Ljubica Harhaji-Trajkovic, Maja Misirkic-Marjanovic, Kristina Janjetovic, Ljubica Vucicevic, Sladjana Kostic-Rajacic, Andre Schrattenholz, Aleksandra Isakovic, Vukic Soskic, Vladimir Trajkovic
ChemMedChem, February 1, 2012, DOI: 10.1002/cmdc.201100537. Read article.

The σ-Hole Phenomenon of Halogen Atoms Forms the Structural Basis of the Strong Inhibitory Potency of C5 Halogen Substituted Glucopyranosyl Nucleosides towards Glycogen Phosphorylase b

2012-01-20T:+05:00

On halogenated ground: C5 halogen substituted glucopyranosyl nucleosides have been discovered as some of the most potent inhibitors of glycogen phosphorylase. The ability of the halogen atom to form intermolecular electrostatic interactions through the σ-hole phenomenon rather than by steric effects alone is the structural basis behind their improved inhibitory potential over the unsubstituted ligand.

[Full Paper]
Anastasia L. Kantsadi, Joseph M. Hayes, Stella Manta, Vicky T. Skamnaki, Christos Kiritsis, Anna-Maria G. Psarra, Zissis Koutsogiannis, Athina Dimopoulou, Stavroula Theofanous, Nikolaos Nikoleousakos, Panagiotis Zoumpoulakis, Maria Kontou, George Papadopoulos, Spyros E. Zographos, Dimitris Komiotis, Demetres D. Leonidas
ChemMedChem, January 20, 2012, DOI: 10.1002/cmdc.201100533. Read article.

Design, Synthesis, and Biological Activity of Hydroxamic Tertiary Amines as Histone Deacetylase Inhibitors

2012-01-25T:+05:00

Linear thought process: Non-peptide linear compounds equipped with hydroxamic groups as the metal binder were explored for their effect on histone deacetylase activity. Herein we report docking studies, synthesis, and biological evaluation of this new generation of hydroxamic tertiary amines.

[Full Paper]
Stefania Terracciano, Maria Giovanna Chini, Raffaele Riccio, Ines Bruno, Giuseppe Bifulco
ChemMedChem, January 25, 2012, DOI: 10.1002/cmdc.201100531. Read article.

Diarylheterocycle Core Ring Features Effect in Selective COX-1 Inhibition

2012-01-25T:+05:00

Getting to the core: The role of the central nucleus in the diarylheterocycle COX-1 inhibitor class was investigated. We identified 5-(furan-2-yl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole (17) as a selective inhibitor of COX-1 activity. The results of molecular docking studies shed light the binding mode of 17 into the catalytic site of COX-1.

[Full Paper]
Maria Grazia Perrone, Paola Vitale, Paola Malerba, Angela Altomare, Rosanna Rizzi, Antonio Lavecchia, Carmen Di Giovanni, Ettore Novellino, Antonio Scilimati
ChemMedChem, January 25, 2012, DOI: 10.1002/cmdc.201100530. Read article.

Discovery of Novel 2-N-Aryl-Substituted Benzenesulfonamidoacetamides: Orally Bioavailable Tubulin Polymerization Inhibitors with Marked Antitumor Activities

2012-02-06T:+05:00

The latest and greatest: Structural optimization of an in-house screening hit afforded a novel class of benzenesulfonamides as orally bioavailable and potent tubulin polymerization inhibitors. These compounds act as antimitotic agents and exhibit a tubulin binding mechanism similar to that of colchicine. The most potent analogues have in vivo antitumor efficacy and are able to circumvent P-glycoprotein-mediated multidrug resistance in tumor cells.

[Full Paper]
Zulong Liu, Zuyu Zhou, Wei Tian, Xing Fan, Ding Xue, Long Yu, Qiang Yu, Ya-Qiu Long
ChemMedChem, February 6, 2012, DOI: 10.1002/cmdc.201100529. Read article.

Discovery of Selective Alpha_2C Adrenergic Receptor Agonists

2012-01-19T:+05:00

Something to ease the pain: Chemical modification of a 2-amino-oxazoline scaffold led to the identification of α_2C adrenergic receptor (AR) agonists. These ligands were characterized by a dual α_2C-AR agonist/α_2A-AR antagonist profile. Structure–activity relationships were studied, and screening in anesthetized rats demonstrated a superior margin of safety for this class of compounds with respect to cardiovascular effects compared with nonselective α₂-AR agonists.

[Communication]
Eric Jnoff, Bernard Christophe, Philippe Collart, Francis Coloretti, Aurel Debeuckelaere, Marc De Ryck, Bruno Fuks, Christophe Genicot, Michel Gillard, Michel Guyaux, Nathalie Price, Marie-Christine Vandergeten, Céline Vermeiren
ChemMedChem, January 19, 2012, DOI: 10.1002/cmdc.201100528. Read article.

Chiral Mercaptoacetamides Display Enantioselective Inhibition of Histone Deacetylase 6 and Exhibit Neuroprotection in Cortical Neuron Models of Oxidative Stress

2012-01-10T:+05:00

Isoform-selective histone deacetylase (HDAC) inhibitors containing mercaptoacetamide zinc binding groups are known to be viable alternatives to the more traditional hydroxamic acid based inhibitors. Herein we demonstrate the HDAC6 enantioselectivity of α-methyl-substituted mercaptoacetamides and provide evidence to support their use as neuroprotective agents.

[Full Paper]
Jay H. Kalin, Hankun Zhang, Sophie Gaudrel-Grosay, Giulio Vistoli, Alan P. Kozikowski
ChemMedChem, January 10, 2012, DOI: 10.1002/cmdc.201100522. Read article.

Discovery of 2-(2-Benzoxazoyl amino)-4-Aryl-5-Cyanopyrimidine as Negative Allosteric Modulators (NAMs) of Metabotropic Glutamate Receptor 5 (mGlu₅): From an Artificial Neural Network Virtual Screen to an In Vivo Tool Compound

2012-01-20T:+05:00

From ANNs to NAMs! Data from an experimental metabotropic glutamate receptor 5 (mGlu₅) high-throughput screen (HTS) were employed to train artificial neural networks (ANNs) based on 345 confirmed negative allosteric modulators (NAMs) and 155 774 inactive compounds. This effort identified two potent mGlu₅ NAMs with a unique chemotype. Optimization afforded a tool compound (shown), active in mouse models of anxiety and addiction.

[Communication]
Ralf Mueller, Eric S. Dawson, Jens Meiler, Alice L. Rodriguez, Brian A. Chauder, Brittney S. Bates, Andrew S. Felts, Jeffrey P. Lamb, Usha N. Menon, Sataywan B. Jadhav, Alexander S. Kane, Carrie K. Jones, Karen J. Gregory, Colleen M. Niswender, P. Jeffrey Conn, Christopher M. Olsen, Danny G. Winder, Kyle A. Emmitte, Craig W. Lindsley
ChemMedChem, January 20, 2012, DOI: 10.1002/cmdc.201100510. Read article.

Novel 4-Amino Bis-pyridinium and Bis-quinolinium Derivatives as Choline Kinase Inhibitors with Antiproliferative Activity against the Human Breast Cancer SKBR-3 Cell Line

2012-01-25T:+05:00

Hitting the spot! There is significant interest in the development of selective and potent choline kinase (ChoK) inhibitors for use as pharmacological tools. ChoK inhibitors with either bis-pyridinium or bis-quinolinium scaffolds exhibit mixed inhibition with a predominantly competitive component. The most active compounds have antiproliferative activities of ~1 μM against the SKBR3 cell line and are much more potent than the choline homologue hemicholinium-3.

[Full Paper]
Verónica Gómez-Pérez, Theresa McSorley, Wei Cun See Too, Manfred Konrad, Joaquín M. Campos
ChemMedChem, January 25, 2012, DOI: 10.1002/cmdc.201100505. Read article.

Dipeptidyl Peptidase IV (DPPIV/CD26)-Based Prodrugs of Hydroxy-Containing Drugs

2012-02-03T:+05:00

Improve stability and solubility! Tripeptide prodrugs of a variety of hydroxy-containing drugs exhibiting fair chemical stability are efficiently hydrolyzed by DPPIV/CD26 to ester valyl intermediates, which spontaneously release the parent drug. A number of these prodrugs have significantly higher water solubility than their poorly soluble parent compounds.

[Full Paper]
Alberto Diez-Torrubia, Silvia Cabrera, Anne-Marie Lambeir, Jan Balzarini, María-José Camarasa, Sonsoles Velázquez
ChemMedChem, February 3, 2012, DOI: 10.1002/cmdc.201100504. Read article.

Selective Agonists for Dopamine/Neurotensin Receptor Heterodimers

Susanne Koschatzky, Peter Gmeiner — 2011-12-23T:+05:00

Select the right pair: Radioligand binding studies of the physical interaction between co-expressed dopamine D_2L or D₃ and neurotensin NTS₁ or NTS₂ receptors indicate substantial cross-inhibitory effects of both NTS₁ and NTS₂ receptor subtypes on the agonist binding of D_2L or D₃ in the presence of neurotensin (NT). D₃–NTS₂ co-expression gave a 20-fold decrease in affinity for biphenylcarboxamide 5 in the presence of NT.

[Full Paper]
Susanne Koschatzky, Peter Gmeiner
ChemMedChem, December 23, 2011, DOI: 10.1002/cmdc.201100499. Read article.

A Benzopyrane Derivative as a P-Glycoprotein Stimulator: A Potential Agent to Decrease β-Amyloid Accumulation in Alzheimer’s Disease

2011-12-23T:+05:00

A simulating interaction: The P-glycoprotein (P-gp) ligand 13 displays high P-gp interacting activity (EC₅₀=2.90 μM) and selectivity in tumor cell lines. Here, this promising compound was further evaluated ex vivo in an everted gut sac assay and found to behave as a P-gp stimulator, making this agent a potential lead for the development of new therapeutics to treat Alzheimer's disease.

[Communication]
Marialessandra Contino, Mariangela Cantore, Elena Capparelli, Maria Grazia Perrone, Mauro Niso, Carmela Inglese, Francesco Berardi, Marcello Leopoldo, Roberto Perrone, Nicola Antonio Colabufo
ChemMedChem, December 23, 2011, DOI: 10.1002/cmdc.201100469. Read article.

Synthesis, in vitro Cytotoxicity, and Interaction with DNA of Platinum(II) Complexes with N-Monocycloalkyl Derivatives of 1R,2R-Diaminocyclohexane as Carrier Ligands

Yanyan Sun, Shaohua Gou, Fei Liu, Runting Yin, Lei Fang — 2012-01-13T:+05:00

Platinum(II) complexes: Oxaliplatin derivatives, especially 1 f and 2 f, show similar or superior cytotoxicity to oxaliplatin. The apoptotic mechanism of complex 2 f and its ability to cause S-phase cell-cycle arrest were determined by flow cytometry. This compound has the capacity to distort DNA through a binding mode distinct from that of oxaliplatin.

[Full Paper]
Yanyan Sun, Shaohua Gou, Fei Liu, Runting Yin, Lei Fang
ChemMedChem, January 13, 2012, DOI: 10.1002/cmdc.201100467. Read article.

Huprine Derivatives as Sub-Nanomolar Human Acetylcholinesterase Inhibitors: From Rational Design to Validation by X-ray Crystallography

2011-11-04T:+05:00

This complete study—from rational design to validation by X-ray crystallography—allowed us to discover two sub-nanomolar hAChE inhibitors (430 and 530 pM) grafted with an easily derivatized linker directed toward the AChE peripheral site. The crystal structure of mouse AChE in complex with compound 4 was solved and confirms the favorable position of the triazole in the active site gorge, paving the way for a new class of bifunctional ligands.

[Communication]
Cyril Ronco, Eugénie Carletti, Jacques-Philippe Colletier, Martin Weik, Florian Nachon, Ludovic Jean, Pierre-Yves Renard
ChemMedChem, November 4, 2011, DOI: 10.1002/cmdc.201100438. Read article.

Why as a Medicinal Chemist I Am Not Optimistic about the Possibility of Finding, in a Reasonable Timeframe, Small-Molecule Drugs Capable of Curing the Evolution of Alzheimer’s Disease

Jean-Louis Kraus — 2011-10-11T:+05:00

[Viewpoint]
Jean-Louis Kraus
ChemMedChem, October 11, 2011, DOI: 10.1002/cmdc.201100431. Read article.

High-Affinity, Selective σ Ligands of the 1,2,3,4-Tetrahydro-1,4'-silaspiro[naphthalene-1,4'-piperidine] Type: Syntheses, Structures, and Pharmacological Properties

2011-11-11T:+05:00

C/Si switch: We report the syntheses and pharmacological properties of novel silicon analogues of σ ligands of the 1'-organyl-1,2,3,4-tetrahydrospiro[naphthalene-1,4'-piperidine] type. C/Si exchange leads to a moderate increase in σ₁ receptor affinity and to a considerable improvement in σ₁/σ₂ selectivity.

[Full Paper]
Reinhold Tacke, Rüdiger Bertermann, Christian Burschka, Steffen Dörrich, Markus Fischer, Barbara Müller, Géraldine Meyerhans, Dirk Schepmann, Bernhard Wünsch, Ingvar Arnason, Ragnar Bjornsson
ChemMedChem, November 11, 2011, DOI: 10.1002/cmdc.201100423. Read article.

An Efficient Mixed-Ligand Pd Catalytic System to Promote C-N Coupling for the Synthesis of N-Arylaminotriazole Nucleosides

2012-01-20T:+05:00

Make it unique! A mixed-ligand system of Pd/Synphos/Xantphos promotes effective C-N coupling in the synthesis of various N-arylaminotriazole and N-arylaminopurine nucleoside analogues. This catalytic system is strikingly powerful and efficient, allowing for unparalleled substrate scope and high product yields as well as promotion of C-Cl bond activation for C-N coupling (see scheme).

[Communication]
Yuting Fan, Yi Xia, Jingjie Tang, Fabio Ziarelli, Fanqi Qu, Palma Rocchi, Juan L. Iovanna, Ling Peng
Chem. Eur. J., January 20, 2012, DOI: 10.1002/chem.201103918. Read article.

Cooperative Catalytic Reactions Using Distinct Transition-Metal Catalysts: Ruthenium- and Copper-Catalyzed Enantioselective Propargylic Alkylation

Masahiro Ikeda, Yoshihiro Miyake, Yoshiaki Nishibayashi — 2012-02-01T:+05:00

Homogeneous catalysis: Highly enantioselective propargylic alkylations of propargylic alcohols with β-ketoesters in the presence of a thiolate-bridged diruthenium complex and a copper complex are presented (see scheme). This methodology based on a cooperative catalytic system using distinct transition metals realizes a useful transformation that cannot be achieved by a single catalyst.

[Full Paper]
Masahiro Ikeda, Yoshihiro Miyake, Yoshiaki Nishibayashi
Chem. Eur. J., February 1, 2012, DOI: 10.1002/chem.201103892. Read article.

Unprecedented Organoimido-Derivatised Lacunary Polyoxometalates

Jian Hao, Jin Zhang, Panchao Yin, Zicheng Xiao, Fengping Xiao, Yongge Wei — 2012-02-01T:+05:00

An organoimido-substituted monovacant hexamolybdate containing additional multidentate ligands and its phenylphosphonate derivative were both synthesized directly from an aromatic amine by using an N,N-dicyclohexylcarbodiimide (DCC) protocol. The inherent chirality of these compounds and their hydrophobic shells are pictured.

[Communication]
Jian Hao, Jin Zhang, Panchao Yin, Zicheng Xiao, Fengping Xiao, Yongge Wei
Chem. Eur. J., February 1, 2012, DOI: 10.1002/chem.201103830. Read article.

Enhancing Anisotropy Barriers of Dysprosium(III) Single-Ion Magnets

2012-02-03T:+05:00

Magnetic personality: The incorporation of a bulky auxiliary ligand in β-diketone-based dysprosium(III) single-ion magnets (SIMs) remarkably increases the anisotropic barriers, representing a promising route toward the design of higher anisotropic barrier SIMs (see scheme).

[Communication]
Gong-Jun Chen, Yun-Nan Guo, Jin-Lei Tian, Jinkui Tang, Wen Gu, Xin Liu, Shi-Ping Yan, Peng Cheng, Dai-Zheng Liao
Chem. Eur. J., February 3, 2012, DOI: 10.1002/chem.201103816. Read article.

Synthesis of Optically Active Oxazoline Derivatives via Catalytic Asymmetric Desymmetrization of 1,3-Diols

Yutaro Tsuda, Masami Kuriyama, Osamu Onomura — 2012-02-01T:+05:00

Chiral oxazolines: A synthetic method to prepare optically active oxazolines through a copper-catalyzed asymmetric desymmetrization of 1,3-diols has been successfully developed. This reaction system tolerated a diverse range of substrates to give the desired oxazoline derivatives in good to excellent yields with high enantioselectivities (see scheme).

[Communication]
Yutaro Tsuda, Masami Kuriyama, Osamu Onomura
Chem. Eur. J., February 1, 2012, DOI: 10.1002/chem.201103800. Read article.

Simple Synthesis of Platinum Dendritic Aggregates Supported on Conductive Tungsten Oxide Nanowires as High-Performance Methanol Oxidation Electrocatalysts

Youngjin Ye, Jin Joo, Byungkwon Lim, Jinwoo Lee — 2012-02-03T:+05:00

Morphology-controlled Pt dendritic aggregates supported on W₁₈O₄₉ nanowires were fabricated by the simple colloidal method. The synthesized nanocatalysts exhibit strong catalytic activity toward methanol oxidation and high CO tolerance because of the highly branched structure of the dendritic Pt nanostructures and assistant catalytic activity of the tungsten oxide nanowires (see figure).

[Communication]
Youngjin Ye, Jin Joo, Byungkwon Lim, Jinwoo Lee
Chem. Eur. J., February 3, 2012, DOI: 10.1002/chem.201103720. Read article.

Morphing the Torsional Potential Energy Function from Local to Global Symmetry through a π Link: The Rotational Spectrum of α,α,α-Trifluoro-p-tolualdehyde

Laura B. Favero, Jens-Uwe Grabow, Walther Caminati — 2012-02-03T:+05:00

Dynamics and inertia: The rotation of the CF₃ top in α,α,α-trifluorotoluene becomes considerably hindered by a V₃ barrier in α,α,α-trifluoro-p-tolualdehyde. Situated in a local V₆ environment, the V₃ barrier is caused by the aldehyde group and communicated through the aromatic π system. Quite dramatically, the ground state inertial defect jumps from −1.271 to −89.961 uÅ², thus reflecting the electronically induced rigidity (see figure).

[Communication]
Laura B. Favero, Jens-Uwe Grabow, Walther Caminati
Chem. Eur. J., February 3, 2012, DOI: 10.1002/chem.201103708. Read article.

Synthesis, Electrochemical Properties and Self-Assembly of a Proton-Conducting Core–Shell Macromolecule

2012-01-26T:+05:00

Let the protons flow: The synthesis of a core–shell macromolecule bearing phosphonic acids is presented. The rigid central core serves as a scaffold to stabilize the flexible polymer shells. Pronounced proton conductivity is obtained under humidified conditions. The self-assembly of such dendritic macromolecules by electrostatic interactions on a modified gold substrate is investigated and characterized.

[Communication]
Meizhen Yin, Naiwen Kang, Guanglei Cui, Zhihong Liu, Feng Wang, Wantai Yang, Markus Klapper, Klaus Müllen
Chem. Eur. J., January 26, 2012, DOI: 10.1002/chem.201103649. Read article.

Light-Harvesting Hybrid Assemblies

K. Venkata Rao, K. K. R. Datta, Muthusamy Eswaramoorthy, Subi. J. George — 2012-01-31T:+05:00

Glowing hybrids: An organic–inorganic approach has generated a variety of light-harvesting hybrid assemblies, with different physical nature based on their design (see scheme). We introduce these design concepts (covalent, semicovalent, and noncovalent approaches) involved in the synthesis of artificial photosynthetic hybrids (MOF=metal–organic framework; PMO=periodic mesoporous organosilica).

[Concept]
K. Venkata Rao, K. K. R. Datta, Muthusamy Eswaramoorthy, Subi. J. George
Chem. Eur. J., January 31, 2012, DOI: 10.1002/chem.201103601. Read article.

Intermolecular Communication on a Liposomal Membrane: Enzymatic Amplification of a Photonic Signal with a Gemini Peptide Lipid as a Membrane-Bound Artificial Receptor

Masaru Mukai, Kohei Maruo, Yoshihiro Sasaki, Jun-ichi Kikuchi — 2012-02-06T:+05:00

trans-formers: A supramolecular system that is capable of activating an enzyme through photoisomerization was constructed on a liposomal membrane. Quantitative evaluation of the present system by using CD and UV spectroscopy showed that enzyme activity was effectively regulated by the specific recognition of the photonic signal by the receptor and its response (see Scheme).

[Full Paper]
Masaru Mukai, Kohei Maruo, Yoshihiro Sasaki, Jun-ichi Kikuchi
Chem. Eur. J., February 6, 2012, DOI: 10.1002/chem.201103552. Read article.

A Concise Total Synthesis of Deoxyschizandrin and Exploration of Its Antiproliferative Effects and those of Structurally Related Derivatives

2012-02-03T:+05:00

A concise total synthesis of the natural product deoxyschizandrin, based around a double organocuprate oxidation strategy, is reported. In addition, the results of biological studies exploring the ability of deoxyschizandrin and synthetic precursors lacking the medium ring biaryl unit to inhibit the proliferation of a human cancer cell line are presented.

[Full Paper]
Shaojun Zheng, Sarah J. Aves, Luca Laraia, Warren R. J. D. Galloway, Kurt G. Pike, Wenjun Wu, David R. Spring
Chem. Eur. J., February 3, 2012, DOI: 10.1002/chem.201103530. Read article.

Formation of a Hydrogen-Bonded Heptazine Framework by Self-Assembly of Melem into a Hexagonal Channel Structure

Sophia J. Makowski, Pia Köstler, Wolfgang Schnick — 2012-02-07T:+05:00

The s-heptazine compound melem C₆N₇(NH₂)₃ assembles into a hydrogen-bonded hexagonal framework in hot aqueous solution (see figure). The structure exhibits infinite channels with diameter of 8.9 Å that are filled with crystal water. TG/DTA measurements, solid-state NMR spectroscopy, powder X-ray diffraction, and sorption measurements have been employed to investigate the thermal behavior of the material, the possibility of hydrolysis, and structural changes induced by dehydration.

[Full Paper]
Sophia J. Makowski, Pia Köstler, Wolfgang Schnick
Chem. Eur. J., February 7, 2012, DOI: 10.1002/chem.201103527. Read article.

A Time-Resolved In Situ Quick-XAS Investigation of Thermal Activation of Fischer–Tropsch Silica-Supported Cobalt Catalysts

2012-02-03T:+05:00

Quick X-ray absorption spectroscopy (XAS) provides quantitative information about the composition of supported metal phases during catalyst activation. Decomposition of SiO₂-supported cobalt nitrate in diluted NO leads to the rapid formation of cobalt(II) hydroxynitrates below 100 °C. Their decomposition starts progressively between 110 and 170 °C to give cobalt oxide nuclei, which contribute to the enhancement of the metal oxide dispersion (see figure).

[Communication]
Jingping Hong, Eric Marceau, Andrei Y. Khodakov, Anne Griboval-Constant, Camille La Fontaine, Valérie Briois
Chem. Eur. J., February 3, 2012, DOI: 10.1002/chem.201103509. Read article.

Highly Diastereoselective Construction of Fused Carbocycles from Cyclopropane-1,1-dicarboxylates and Cyclic Enol Silyl Ethers: Scope, Mechanism, and Origin of Diastereoselectivity

Jian-Ping Qu, Yong Liang, Hao Xu, Xiu-Li Sun, Zhi-Xiang Yu, Yong Tang — 2012-01-20T:+05:00

Cyclopropane rings true: By selecting the appropriate substituents on the ester and silyl groups, fused cyclopentane derivatives with multiple contiguous stereocenters can be synthesized with excellent diastereoselectivity through Cu^II/bisoxazoline-catalyzed intermolecular [3+2] cycloaddition reactions of cyclopropane-1,1-dicarboxylates and cyclic enol silyl ethers (see scheme).

[Communication]
Jian-Ping Qu, Yong Liang, Hao Xu, Xiu-Li Sun, Zhi-Xiang Yu, Yong Tang
Chem. Eur. J., January 20, 2012, DOI: 10.1002/chem.201103495. Read article.

Determination of the Absolute Configuration of Peptide Natural Products by Using Stable Isotope Labeling and Mass Spectrometry

2012-01-20T:+05:00

Game over—structure solved: A combination of labeling experiments with mass spectrometry results in the reliable determination of the sum formula, the nature of the building blocks, and for peptide natural products also the determination of the absolute configuration as exemplified for the novel natural products GameXPeptide A–D (see scheme).

[Full Paper]
Helge B. Bode, Daniela Reimer, Sebastian W. Fuchs, Ferdinand Kirchner, Christina Dauth, Carsten Kegler, Wolfram Lorenzen, Alexander O. Brachmann, Peter Grün
Chem. Eur. J., January 20, 2012, DOI: 10.1002/chem.201103479. Read article.

Photoreversible Supramolecular Polymerisation and Hierarchical Organization of Hydrogen-Bonded Supramolecular Co-polymers Composed of Diarylethenes and Oligothiophenes

2012-01-31T:+05:00

Designer photoresponsive assemblies: Oligothiophenes and diarylethenes are held together by multiple hydrogen bonds, affording photoresponsive and electroacitve supramolecular copolymers. The co-polymer chains hierarchically organize into helical nanorods, which can be reversibly converted to small oligomeric species upon irradiation with UV and visible light (see figure).

[Full Paper]
Shiki Yagai, Keisuke Ohta, Marina Gushiken, Kazunori Iwai, Atsushi Asano, Shu Seki, Yoshihiro Kikkawa, Masakazu Morimoto, Akihide Kitamura, Takashi Karatsu
Chem. Eur. J., January 31, 2012, DOI: 10.1002/chem.201103465. Read article.

X-ray Crystallographic Proof of the Isomer D₂-C₈₄(5) as Trifluoromethylated and Chlorinated Derivatives, C₈₄(CF₃)₁₆, C₈₄Cl₂₀, and C₈₄Cl₃₂

2012-01-26T:+05:00

Minor isomer comes forward: Minor isomer C₈₄(5) has been captured by high temperature trifluoromethylation with CF₃I and chlorination with VCl₄. The compounds C₈₄(CF₃)₁₆, C₈₄Cl₂₀, and C₈₄(5)Cl₃₂ were investigated by X-ray crystallography providing the first direct proofs of the cage connectivity of D₂-C₈₄(5). The D₂-C₈₄(5)Cl₃₂ molecule (see figure; C grey, Cl green) contains two flattened, pyrene-like substructures on opposite poles of the cage resulting in its drum-like shape.

[Communication]
Shangfeng Yang, Chuanbao Chen, Tao Wei, Nadezhda B. Tamm, Erhard Kemnitz, Sergey I. Troyanov
Chem. Eur. J., January 26, 2012, DOI: 10.1002/chem.201103456. Read article.

An Approach to the Regioselective Diamination of Conjugated Di- and Trienes

Anton Lishchynskyi, Kilian Muñiz — 2012-01-25T:+05:00

It’s do or diaminate: The selective diamination of 1,3-butadienes in the presence of hypervalent iodine reagents has been developed. This oxidation process proceeds with complete selectivity in favor of diamination. Depending on the substrate, it proceeds either with 1,2- or 1,4-regioselectivity (see scheme).

[Communication]
Anton Lishchynskyi, Kilian Muñiz
Chem. Eur. J., January 25, 2012, DOI: 10.1002/chem.201103435. Read article.

Chemistry articles from Wiley-VCH/ChemPubSoc Europe

Opening Up the World of Chemistry

Determining the Role of the Aromatic Ring of N-Arylmethyl ent-conduramine F-1 in their Interactions with α-Glucosidases by Saturation Transfer Difference NMR Spectroscopy Experiments

Semi-Synthesis and Analysis of Chemically Modified Zif268 Zinc-Finger Domains

Ti/Ni-Based Multimetallic System for the Efficient Allylation of Carbonyl Compounds

Oxidative Homologation of Aldehydes to α-Ketoaldehydes by using Iodoform, o-Iodoxybenzoic Acid, and Dimethyl Sulfoxide

Replacement of HMPA in Samarium Diiodide Promoted Cyclizations and Reactions of Organolithium CompoundsDedicated to Professor Dr. Gerhard Erker on the occasion of his 65th birthday

New Linearly and Angularly Fused Quinazolinones: Synthesis through Gold(I)-Catalyzed Cascade Reactions and Anticancer Activities

Synthesis of Isoxazole Triflones

Stereocontrolled Synthesis of the cis-Hydroxydecalin System: Towards Biologically Active 19-nor-Clerodanes

Asymmetric Organocatalytic Michael Addition–Cyclization Cascade Reaction of Nitroalkanes with o-Hydroxycinnamaldehydes

Solvent-Free Tandem Synthesis of 2-Thiazolines and 2-Oxazolines Catalyzed by a Copper Catalyst

Practical Synthesis of Unsymmetrical Diarylacetylenes from Propiolic Acid and Two Different Aryl Bromides

Asymmetric Michael Addition Reactions between 3-Substituted Benzofuran-2(3H)-ones and 1,1-Bis(phenylsulfonyl)ethylene Catalyzed by Bifunctional Catalysts Containing Tertiary Amine and Thiourea Groups

Bis- and Tris-Alkyne Phosphoramidites for Multiple 5'-Labeling of Oligonucleotides by Click Chemistry

Development of a Solid-Phase Approach to the Natural Product Class of Ahp-Containing Cyclodepsipeptides

Synthesis of Modified Phenylalanine Peptides by Cross Enyne Metathesis and a Diels–Alder Reaction as Key Steps

Asymmetric Allylboration of Aldehydes with Pinacol Allylboronates Catalyzed by 1,1'-Spirobiindane-7,7'-diol (SPINOL) Based Phosphoric Acids

A One-Pot Three-Step Synthesis of Z-Trisubstituted Olefins from Arylalkynes and Their Cyclization into 4-Aryl-2H-chromenes

Asymmetric Benzoylation of meso-Hydrobenzoin Using a Reusable Tripodal Imidazoline–Pyridine–Cu Catalyst

A Novel Type of Chiral Triangulane-Based Diphosphane Ligands for Transition MetalsSee ref.1

Cicindeloine from Stenus cicindeloides – Isolation, Structure Elucidation, and Total Synthesis

Synthesis of a Photochromic Fused 2H-Chromene Capable of Generating a Single Coloured Species

A Photodynamic Library of Tetrasulfinylcalix[4]arenes: The Sulfinyl Dance

Klebsiella pneumoniae (NBRC 3319) Mediated Asymmetric Reduction of α-Substituted β-Oxo Esters and Its Application to the Enantioiselective Synthesis of Small-Ring Carbocycle Derivatives

The Oxy-Cope Rearrangement of Aldol Products. A Combined Experimental and Theoretical Study

Stereoselective Olefination and Regiospecific Vicinal Difunctionalization of Imines with α-(Benzothiazol-2-ylsulfonyl) Carbonyl Compounds

Total Synthesis of (+)-Aspicilin by an Alkyne-Based Approach and Its Biological Evaluation

Palladium-Catalyzed Tandem Reactions of β-(2-Bromophenyl)-α,β-Unsaturated Carbonyl Compounds with 2-Hydroxyphenylboronic Acid: A New Route to Benzo[c]chromenes

Synthesis of 6-Substituted 2(1H)-Pyridon-3-yl C-2'-Deoxyribonucleosides

An Efficient Route to Quinolines and Other Compounds by Iron-Catalysed Cross-Dehydrogenative Coupling Reactions of Glycine Derivatives

Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids to Indolylnitroalkenes

Preparation of New 1,4-Diazocanes as Scaffolds for Combinatorial Chemistry

Controlling the Macroscopic Chirality of Organic Materials Based on 1,3,5-TrialkynylbenzenesDedicated to Dr. Helmut Sonnenschein on the occasion of his 60th birthday

Effects of Silyl Substituents on the Palladium-Catalyzed Asymmetric Synthesis of Axially Chiral (Allenylmethyl)silanes and Their SE2' Chirality Transfer Reactions

Selective Saccharide Recognition Using Modular Diboronic Acid Fluorescent Sensors

Promiscuous Behavior of Rhizomucor miehei Lipase in the Synthesis of N-Substituted β-Amino Esters

A BODIPY-Based Highly Selective Fluorescent Chemosensor for Hg2+ Ions and Its Application in Living Cell Imaging

Dendritic Architectures with Positively Charged Cores and Negatively Charged Shells

1,2,4-Oxadiazole 4-Oxides as Nitrones in 1,3-Dipolar Cycloaddition Reactions to Vinyl Ethers

Synthetic Studies of Sesquiterpenes with the Dunniane Skeleton

Biosynthesis and Total Synthesis Studies on the Jadomycin Family of Natural Products

A Carbohydrate-Based Synthesis of the C13–C22 Fragment of Amphidinolide X

The First Stereoselective Total Synthesis of Putaminoxin E and Its Epimer and Evaluation of Their Biological PropertiesSynthetic Studies on Natural Products, 53; Part 52: D. B. Shinde, B. S. Kanth, M. Srilatha, B. Das, Synthesis 2011, in press.

Synthesis, Structure and Conformation of Terphenylene-Derived OxacalixaromaticsDedicated to Professor Wen-Qi Chen on the occasion of his 80th birthday

Regioselective Photochemical C–OMe Bond Formation Initiated by One-Electron Transfer and N–OMe Bond Fragmentation in Electron Donor–Acceptor SystemsDedicated to the memory of Rafael Suau

Complex-Induced Proximity Effect in the Regioselective Lithiation of Pyridine Derivatives

Assignment of Absolute Configuration of Bis-γ-pyrone Polypropionates from Marine Pulmonate Molluscs

Design of New Tetrazine–Triphenylamine Bichromophores – Fluorescent Switching by Chemical Oxidation

Synthesis and Study of Oxadisilole-Fused Benzisoxazoles or Naphthisoxazoles

Synthesis and Evaluation of Lipophilic BTBP Ligands for An/Ln Separation in Nuclear Waste Treatment: The Effect of Alkyl Substitution on Extraction Properties and Implications for Ligand Design

Biosynthesis of Defensive Coccinellidae Alkaloids: Incorporation of Fatty Acids in Adaline, Coccinelline, and Harmonine

An Ammonia-Triggered Stereocontrolled Conversion of a γ-Lactone to the Central Tetrahydropyran of Pederin, Psymberin, and Onnamides D–FDedicated to Professor Philip Kocienski, FRS

N1-Functionalized Indole-Phosphane Oxazoline (IndPHOX) Ligands in Asymmetric Allylic Substitution Reactions

Stereoselective Dihydroxylation Reaction of Alkenyl β-D-Hexopyranosides: A Methodology for the Synthesis of Glycosylglycerol Derivatives and 1-O-Acyl-3-O-β-D-glycosyl-sn-glycerol Analogues

The New Age of Electrophilic Perfluoroalkylation ReactionsDedicated to the memory of Professor Lev Yagupolskii

Highly Enantioselective Synthesis of Spiro[cyclohexanone-oxindoles] and Spiro[cyclohexanone-pyrazolones] by Asymmetric Cascade [5+1] Double Michael Reactions

Recent Advances in the Total Synthesis of Chlorosulfolipids

Synthesis of Difluoromethyl-Containing α-Acyloxycarboxamide Derivatives through a Passerini Reaction and Desulfonylation

Enantioselective Organocatalytic α-Alkylation of Ketones by SN1-Type Reaction of Alcohols

An Efficient Multigram Synthesis of Alkannin and Shikonin

Rapid Room-Temperature 11C-Methylation of Arylamines with [11C]Methyl Iodide Promoted by Solid Inorganic-Bases in DMF

Trapping and Analysing Wheland–Meisenheimer σ Complexes, Usually Labile and Escaping Intermediates

Glaser Coupling of 4-Ethynyl[2.2]paracyclophane: The Formation of Two DiastereomersCyclophanes, 68. Part 67: H. Hopf, H. Hinrichs, L. Ernst, P. G. Jones, V. Boekelheide, Isr. J. Chem., in press.

Efficient Synthesis of Arylated Flavones by Site-Selective Suzuki–Miyaura Cross-Coupling Reactions of the Bis(triflate) of 5,7- and 7,8-Dihydroxyflavone

Nonenzymatic Acylative Kinetic Resolution of Racemic Amines and Related Compounds

Tetrakis(tetrathiafulvalene–tetrathiacrown ether)porphyrazine Triads: Synthesis, Photophysical, and Electrochemical Properties

Polynuclear Copper(I) Complexes with Chelating Bis- and Tris-N-Heterocyclic Carbene Ligands: Catalytic Activity in Nitrene and Carbene Transfer Reactions

Towards the Total Synthesis of Mycaperoxide B: Probing Biosynthetic Rationale

N-Acylpyrroles: More Than Amides

Sulfur–Nitrogen and Carbon–Nitrogen Bond Formation by Intermolecular Imination and Amidation without Catalyst

Studies on the Diastereoselective Intramolecular Pauson–Khand Reaction on Regioisomeric Chiral Perhydrobenzoxazines Derived from (–)-8-Aminomenthol

Copper-Catalyzed Cascade Reaction of 4-Iodopyrazole Derivatives with Amidines for the Synthesis of Pyrazolo[4,3-d]pyrimidine DerivativesCDRI Communication Number 8161

Synthesis, Spectroscopic and Thermal Characterization of Azido-1,2,4-triazoles: A Class of Heteroarenes with a High Nitrogen Content

A Synthetic Overview of Radiolabeled Compounds for β-Amyloid Targeting

New Anthracene Derivatives – Structure Elucidation and Antimicrobial Activity

Site-Directed Spin Labelling of Nucleic Acids

Segment Solid-Phase Total Synthesis of the Anthelmintic Cyclooctadepsipeptides PF1022A and Emodepside

Concave Annelated TerpyridinesConcave Reagents, 61; Part 60: D. Stoltenberg, S. Lüthje, O. Winkelmann, C. Näther, U. Lüning, Eur. J. Org. Chem. 2011, 5845–5859.

Silicone-Supported Cinchona Alkaloid Derivatives as Insoluble Organocatalysts in the Enantioselective Dimerization of Ketenes

Replacement of HMPA in Samarium Diiodide Promoted Cyclizations and Reactions of Organolithium Compounds
Dedicated to Professor Dr. Gerhard Erker on the occasion of his 65th birthday

A Novel Type of Chiral Triangulane-Based Diphosphane Ligands for Transition Metals
See ref.¹

Controlling the Macroscopic Chirality of Organic Materials Based on 1,3,5-Trialkynylbenzenes
Dedicated to Dr. Helmut Sonnenschein on the occasion of his 60th birthday

Effects of Silyl Substituents on the Palladium-Catalyzed Asymmetric Synthesis of Axially Chiral (Allenylmethyl)silanes and Their S_E2' Chirality Transfer Reactions

A BODIPY-Based Highly Selective Fluorescent Chemosensor for Hg²⁺ Ions and Its Application in Living Cell Imaging

The First Stereoselective Total Synthesis of Putaminoxin E and Its Epimer and Evaluation of Their Biological Properties
Synthetic Studies on Natural Products, 53; Part 52: D. B. Shinde, B. S. Kanth, M. Srilatha, B. Das, Synthesis 2011, in press.

Synthesis, Structure and Conformation of Terphenylene-Derived Oxacalixaromatics
Dedicated to Professor Wen-Qi Chen on the occasion of his 80th birthday

Regioselective Photochemical C–OMe Bond Formation Initiated by One-Electron Transfer and N–OMe Bond Fragmentation in Electron Donor–Acceptor Systems
Dedicated to the memory of Rafael Suau

An Ammonia-Triggered Stereocontrolled Conversion of a γ-Lactone to the Central Tetrahydropyran of Pederin, Psymberin, and Onnamides D–F
Dedicated to Professor Philip Kocienski, FRS

N¹-Functionalized Indole-Phosphane Oxazoline (IndPHOX) Ligands in Asymmetric Allylic Substitution Reactions

The New Age of Electrophilic Perfluoroalkylation Reactions
Dedicated to the memory of Professor Lev Yagupolskii

Enantioselective Organocatalytic α-Alkylation of Ketones by S_N1-Type Reaction of Alcohols

Rapid Room-Temperature ¹¹C-Methylation of Arylamines with [¹¹C]Methyl Iodide Promoted by Solid Inorganic-Bases in DMF

Glaser Coupling of 4-Ethynyl[2.2]paracyclophane: The Formation of Two Diastereomers
Cyclophanes, 68. Part 67: H. Hopf, H. Hinrichs, L. Ernst, P. G. Jones, V. Boekelheide, Isr. J. Chem., in press.

Copper-Catalyzed Cascade Reaction of 4-Iodopyrazole Derivatives with Amidines for the Synthesis of Pyrazolo[4,3-d]pyrimidine Derivatives
CDRI Communication Number 8161

Concave Annelated Terpyridines
Concave Reagents, 61; Part 60: D. Stoltenberg, S. Lüthje, O. Winkelmann, C. Näther, U. Lüning, Eur. J. Org. Chem. 2011, 5845–5859.

Cu-Catalyzed Enantioselective 1,4-Additions of Aryl-Grignard Reagents to Cyclohexenone in the Presence of TADDOL-Derived Phosphane-Phosphite Ligands
Dedicated to Professor Mohammed A. Omary

Anthracene-Labeled 1,2,3-Triazole-Linked Bispyridinium Amide for Selective Sensing of H₂PO₄^– by Fluorescence and Gel Formation

Synthesis of the Indolic Pentacyclic Core of Manadomanzamine A Following Biogenetically Based Strategies
Dedicated to the memory of François Tillequin

Room-Temperature Sol–Gel Synthesis of Sodium Hexaniobate in an Immiscible Hexane–Water System and Its Conversion into NaNbO₃

Isolation of a New C_s-Symmetrized Mo₃(μ₃-S)(μ-S)(μ-S₂)₂ Structural Type Through Complementary Association with a Cubane-Type Mo₃NiS₄ Cluster

Ca₂NiSn₂ – A Polymorphic Intermetallic Phase: Atomic and Electronic Structure as well as a Topological Description of the Phase Transition by a Sigmatropic-Type Rearrangement of Ni and Sn Atoms

Molecular Structure of a Hydridoniobocene Complex [Nb(η⁵-C₅H₄SiMe₃)₂(H)₃] and Its Use as Catalyst for the Ring-Opening Polymerization of Cyclic Esters

Silver Melonates and Coordination Modes of the Multidentate [C₆N₇(NCN)₃]^3– Anion

Application of Nickel Complexes Modified by Tridentate O,N,O'-Ligands as Precatalysts in Nickel-Catalyzed C(sp²)–C(sp³) Bond Formations

Coordinating Properties of Pyrone and Pyridinone Derivatives, Tropolone and Catechol toward the VO²⁺ Ion: An Experimental and Computational Approach

Derivatives of Photosensitive CORM-S1 – CO Complexes of Iron and Ruthenium with the (OC)₂M(S–C–C–NH₂)₂ Fragment

Fe^III Spin-Crossover Complexes with Photoisomerizable Ligands: Experimental and Theoretical Studies on the Ligand-Driven Light-Induced Spin Change Effect

Synthesis of Oligomeric Zinc Complexes with Bicyclic and Acyclic Guanidinate Ligands
Dedicated to Prof. Dr. mult. Alois Haas on the occasion of his 80th birthday

Expected and Unconventional Ag⁺ Binding Modes in Heteronuclear Pt,Ag Coordination Polymers Derived from trans-[Pt(methylamine)₂(pyrazole)₂]²⁺

[V₁₅Ge₆O₄₂S₆(H₂O)]^12–, a Thiogermanatopolyoxovanadate Cluster Featuring the Spin Topology of the Molecular Magnet [V₁₅As₆O₄₂(H₂O)]^6–

Structural Conformation and Optical and Electrochemical Properties of Imidazolyl-Substituted Naphthalenediimide and Its Hg^II, Cd^II, and Cu^II Halide Complexes

Conjugation to Biocompatible Dendrimers Increases Lanthanide T₂ Relaxivity of Hydroxypyridinone Complexes for Magnetic Resonance Imaging

Hexaphosphine: A Multifaceted Ligand for Transition Metal Coordination
Dedicated to Professor Philippe Meunier on the occasion of his 65th birthday

Pompon-Like MnF₂ Nanostructures from a Single-Source Precursor through Atmospheric Pressure Chemical Vapor Deposition

Silica Nanoparticles for Bimodal MRI–Optical Imaging by Grafting Gd³⁺ and Eu³⁺/Tb³⁺ Complexes

Syntheses and Structural Study of Novel Tetranuclear Bis(phenoxido)-Bridged Cu^II Metal–Organic Macrocycles

K_β Detected High-Resolution XANES of Fe^II and Fe^III Models of the 2-His-1-Carboxylate Motif: Analysis of the Carboxylate Binding Mode

Rhodium (Thiophosphinoyl)(trimethylsilyl)methanide and Bis(thiophosphinoyl)methanide Complexes: S~S vs. C~S Coordination
Dedicated to the memory of our friend and colleague Pascal Le Floch

Crystal-Phase- and Morphology-Controlled Synthesis of Fe₂O₃ Nanomaterials

One-Dimensional 3d–3d–4f Trimetallic Assemblies Consisting of Cu^II₂Ln^III Trinuclear Complexes and Hexacyanometallate

Thiolato-Bridged Arene–Ruthenium Complexes: Synthesis, Molecular Structure, Reactivity, and Anticancer Activity of the Dinuclear Complexes [(arene)₂Ru₂(SR)₂Cl₂]
Dedicated to Dr. Hubert Le Bozec on the occasion of his 60th birthday