A Practical Guide to Toxicology and Human Health Risk Assessment
1. Auflage Dezember 2018
400 Seiten, Softcover
Wiley & Sons Ltd
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Toxicology - the study of the adverse effects of chemicals on living organisms is the cornerstone to all aspects of chemical safety and knowledge of the subject is needed in a wide spectrum of fields from the chemical industry to medicine, emergency services, forensics, and regulatory science. Toxicology involves the study of symptoms, mechanisms, treatments and detection of poisoning ... especially the poisoning of people.
The many problems arising from a poor understanding of toxicology and its applications in hazard communication and chemical safety motivated the author's training courses and webinars, leading to this valuable book.
Providing a practical and accessible guide, A Practical Guide to Toxicology and Human Health Risk Assessment enables readers to quickly build up knowledge and understanding of toxicology and its use in hazard identification, which is a fundamental part of chemical risk assessment. The book also covers current toxicological testing strategies and the use of physicochemical test data in hazard identification and exposure assessment.
Examples are provided throughout the book to highlight important issues along with a summary of the key points that have been covered in each of the respective chapters. The book concludes with a listing of online resources on toxicology and risk assessment.
Chapter 3. The Dose Makes the Poison
Chapter 4. Toxicokinetics
Chapter 5. Factors which modify toxicity
Chapter 6. Local effects
Chapter 7.1. Chemical allergies
Chapter 7.2. Genetic toxicology
Chapter 7.3. Carcinogenicity
Chapter 7.4. Reproductive and developmental toxicology
Chapter 8.1. The liver
Chapter 8.2. The Kidney
Chapter 8.3. The immune system
Chapter 8.4. haematopoietic system & blood
Chapter 8.5. The nervous system
Chapter 8.6. The respiratory tract
Chapter 8.7. The endocrine system
Chapter 9.1. Assessment of Irritation & Corrosive Effects
Chapter 9.2. Assessment of acute toxicity
Chapter 9.3. Repeated dose toxicity testing
Chapter 9.4. Assessment of carcinogenicity
Chapter 9.5. Assessment
Chapter 9.6. Assessment of Reproductive & Developmental effects
Chapter 9.7. Assessment of skin and respiratory sensitization
Chapter 10. Alternative methods to animal testing
Chapter 11. Human health risk assessment
Chapter 12. Glossary
