John Wiley & Sons Neglected Tropical Diseases and Phytochemicals in Drug Discovery Cover This book presents novel drug discovery updates from medicinal plants against the devastating effect.. Product #: 978-1-119-61660-3 Regular price: $185.98 $185.98 Auf Lager

Neglected Tropical Diseases and Phytochemicals in Drug Discovery

Egbuna, Chukwuebuka / Akram, Muhammad / Ifemeje, Jonathan Chinenye (Herausgeber)

Cover

1. Auflage Dezember 2021
592 Seiten, Hardcover
Wiley & Sons Ltd

ISBN: 978-1-119-61660-3
John Wiley & Sons

Kurzbeschreibung

This book presents novel drug discovery updates from medicinal plants against the devastating effects of neglected tropical diseases (NTDs) on the global health care system. It is divided into six parts: part 1 presents chapters on general overview on NTDs, the recent drug discovery progress, the various druggable targets and challenges; part 2 presents chapters on protozoan infections; part 3 presents chapters on helminth infections; part 4 presents chapters on bacterial infections; and parts 5 and 6 document chapters on viral, fungal, and ectoparasitic infections.

Jetzt kaufen

Preis: 199,00 €

ca.-Preis

Preis inkl. MwSt, zzgl. Versand

Explore novel drug discovery updates from medicinal plants to help fight the devastating effects of neglected tropical diseases

Neglected Tropical Diseases and Phytochemicals in Drug Discovery delivers a comprehensive exploration of the drug discovery process as it pertains to neglected tropical diseases. The book covers recent advancements in drug discovery, as well as druggable targets and new challenges facing the industry. It offers readers expansive discussions of specific diseases, including protozoan, helminth, bacterial, viral, fungal, and ectoparasitic infections.

This book provides readers with insightful perspectives from leading industry voices on fifty years of trends and progress in the search for new, safe, and affordable therapeutic drugs in the fight against neglected tropical diseases. It includes information beneficial to researchers in a variety of fields of biology, chemistry, medicine, and pharmaceuticals.

The distinguished authors cover topics including the effects of phytochemicals on the causative agent of leprosy and the potential applicability of phytochemicals in the management of Dengue fever. Readers will also enjoy the inclusion of:
* Thorough introductions to neglected tropical diseases, phytochemicals, protein targets, and mechanisms in drug discovery, as well as the epidemiology of neglected tropical diseases
* An exploration of novel bioactive lead compounds for drug discovery against neglected tropical diseases, leishmaniasis, lymphatic filariasis, trypanosomiasis, and schistosomiasis
* Discussions of protozoan infections, including herbal, nutritional, and traditional remedies for giardiasis and the anti-leishmanial potentials of phytochemicals
* Examinations of helminth infections, including the prospects of phytochemicals in the treatment of helminthiasis

Perfect for medicinal chemists, drug developers, and research and development scientists, Neglected Tropical Diseases and Phytochemicals in Drug Discovery will also earn a place in the libraries of toxicologists and researchers in biology, chemistry, medicinal chemistry, ethnobotany, and bioinformatics seeking a one-stop resource for drug discovery for neglected tropical diseases.

Preface

PART I: Introduction to Neglected Tropical Diseases

Chapter 1: Epidemiology of neglected tropical diseases

Kurubaran Ganasegeran

Email: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


Chapter 2: Neglected Tropical Diseases, Phytochemicals, Protein Targets and Mechanisms in Drug Discovery

Lalit R. Samant

Email: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


Chapter 3: Novel bioactive lead compounds for drug discovery against neglected tropical diseases, leishmaniasis, lymphatic filariasis, trypanosomiasis (African sleeping sickness and Chagas disease) and schistosomiasis

Abeer M. El Sayed

E-mail: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


PART II: Protozoan Infections


Chapter 4: Herbal, nutritional and traditional remedies for giardiasis: Phytochemicals as drug candidates

Samrat Bhattacharyya

Email: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


Chapter 5: Antiprotozoal activity of phytochemicals against Entamoeba histolytica, the causative agent of Amoebiasis

Goutam Jena

Email: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


Chapter 6: Anti-leishmanial potentials of phytochemicals

Shahira Mohamed Ezzat

E-mail: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


Part III: Helminth Infections

Chapter 7: Prospects of phytochemicals in the treatment of helminthiasis

Muhammad Akram

Email: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


Chapter 8: Efficacy of phytochemicals of medicinal plants for the treatment of human echinococcosis: Echinococcal disease, hydatidosis or hydatid disease drug discovery

Charles Oluwaseun Adetunji

Email: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


Chapter 9: Filaricidal activity of phytochemicals against lymphatic filariasis

Sharangouda J. Patil

Email: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


Chapter 10: Dracunculiasis (Guinea worm disease) and phytochemicals in drug discovery

Muhammad Akram

E-mail: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!

Chapter 11: Medicinal potentials of phytochemicals as a source of drugs for the treatment of onchocerciasis (River blindness)

Chandrashekar Srinivasa

E-mail: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


Chapter 12: Foodborne trematodiases and phytochemicals

Ramith Ramu

Email: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


Part IV: Bacterial Infections

Chapter 13: Bacteriocidal effects of phytochemicals on Mycobacterium ulcerans, the causative agents of Buruli ulcer

Alloysius Chibuike Ogodo

Email: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


Chapter 14: Bacteriocidal effects of phytochemicals on Mycobacterium leprae, the causative agent of Leprosy

Chukwuebuna Egbuna

E-mail: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


Chapter 15 Medicinal plants and phytochemicals effective against Chlamydia trachomatis, the causative agent of trachoma

Habibu Tijjani

E-mail: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


Chapter 16: Yaws (Endemic treponematoses) drug discovery from phytochemicals: An informatics protocol for drug target identification to phytochemical inhibitor screening and validation

Zarrin Basharat

E-mail: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


Part V: Viral Infections

Chapter 17: Dengue fever: a brief overview and insights into the potential applicability of phytochemicals in its management

Muhammad Akram

E-mail: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!

Chapter 18: Medicinal potentials of phytochemicals for the management of rabies

Chandan Shivamallu

Email: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


Part VI: Fungal and Ectoparasitic Infections

Chapter 19: Roles of medicinal plants in the diagnosis and treatment of Eumycetoma

Chinaza Godswill Awuchi

Email: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


Chapter 20: Role of phytochemicals in the treatment of ectoparasitic infections: Scabies and myiasis

Santwana Palai

E-mail: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


Part VII: Non Classified NTDs: Malaria and Human Tuberculosis

Chapter 21: Malaria and recent developments in antimalarial drugs

Mithun Rudrapal

E-mail: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!


Chapter 22: Therapeutic potentials of phytochemicals against Mycobacterium tuberculosis, the causative agents of Tuberculosis

Alloysius Chibuike Ogodo

Email: Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein! Index