John Wiley & Sons Bioprospecting of Microorganism-Based Industrial Molecules Cover Discover a comprehensive and current overview of microbial bioprospecting written by leading voices .. Product #: 978-1-119-71724-9 Regular price: $179.44 $179.44 Auf Lager

Bioprospecting of Microorganism-Based Industrial Molecules

Singh, Sudhir P. / Upadhyay, Santosh Kumar (Herausgeber)

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1. Auflage Januar 2022
448 Seiten, Hardcover
Wiley & Sons Ltd

ISBN: 978-1-119-71724-9
John Wiley & Sons

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Discover a comprehensive and current overview of microbial bioprospecting written by leading voices in the field

In Bioprospecting of Microorganism-Based Industrial Molecules, distinguished researchers and authors Sudhir P. Singh and Santosh Kumar Upadhyay deliver global perspectives of bioprospecting of biodiversity. The book covers diverse aspects of bioprospecting of microorganisms demonstrating biomass value of nutraceutical, pharmaceutical, biomedical, and bioenergetic importance.

The authors present an amalgamation of translational research on bioresource utilization and ecological sustainability that will further the reader's knowledge of the applications of different microbial diversity and reveal new avenues of research investigation.

Readers will also benefit from:
* A thorough introduction to microbial biodiversity and bioprospecting
* An exploration of anti-ageing and skin lightening microbial products and microbial production of anti-cancerous biomolecules
* A treatment of UV protective compounds from algal biodiversity and polysaccharides from marine microalgal sources
* Discussions of microbial sources of insect toxic proteins and the role of microbes in bio-surfactants production

Perfect for academics, scientists, researchers, graduate and post-graduate students working and studying in the areas of microbiology, food biotechnology, industrial microbiology, plant biotechnology, and microbial biotechnology, Bioprospecting of Microorganism-Based Industrial Molecules is an indispensable guide for anyone looking for a comprehensive overview of the subject.

About the Editors xvi

List of Contributors xviii

Preface xxiii

Acknowledgments xxiv

1 An Introduction to Microbial Biodiversity and Bioprospection 1
Tomoya Shintani, Santosh Kumar Upadhyay, and Sudhir P. Singh

1.1 Introduction 1

1.2 Conclusions and Perspectives 3

Acknowledgment 4

References 4

2 Application of Microorganisms in Biosurfactant Production 6
Lorena Pedraza-Segura, Luis V. Rodríguez-Durán, Gerardo Saucedo- Castañeda, and José de Jesús Cázares-Marinero

2.1 Biosurfactants Nature and Classification 6

2.2 Biosynthesis of BS by Archaea and Bacteria 12

2.3 Biosynthesis of BS by Yeasts and Molds 14

2.4 Screening for BS Producers 15

2.5 A Case Study: SL by Solid-State Fermentation (SSF), Kinetics, and Reactor Size Estimation 16

2.6 Conclusions and Perspectives 23

References 24

3 Microbial Gums: Current Trends and Applications 31
Rwivoo Baruah and Prakash M. Halami

3.1 Introduction 31

3.2 Biosynthesis of Microbial Gums 32

3.3 Production of Microbial Gums 33

3.4 Structure and Properties of Microbial Gums 34

3.5 Types of Microbial Gums 34

3.6 Applications of Microbial Gums 39

3.7 Conclusions and Perspectives 42

Acknowledgments 43

References 43

4 Antiaging and Skin Lightening Microbial Products 47
Prabuddha Gupta, Ujwalkumar Trivedi, Mahendrapalsingh Rajput,Tejas Oza, Jasmita Chauhan, and Gaurav Sanghvi

4.1 Introduction 47

4.2 Aging 48

4.3 Extrinsic Skin Aging Factors 52

4.4 Why Microbes 53

4.5 Conclusions and Perspectives 67

References 68

5 Application of Microorganisms in Bioremediation 77
Himani Thakkar and Vinnyfred Vincent

5.1 Introduction 77

5.2 Microbial Bioremediation 78

5.3 Microbial Bioremediation of Organic Pollutants 79

5.4 Microbial Degradation of Heavy Metals 87

5.5 Factors Affecting Bioremediation 89

5.6 Advances in Bioremediation 91

5.7 Conclusions and Perspectives 94

References 95

6 Microbial Applications in Organic Acid Production 104
Jyoti Singh Jadaun, Amit K. Rai, and Sudhir P. Singh

6.1 Introduction 104

6.2 Glycolic acid (2C) 105

6.3 Acetic Acid (2C) 108

6.4 Pyruvic Acid (3C) 108

6.5 Lactic Acid (3C) 109

6.6 Succinic Acid (4C) 109

6.7 Fumaric Acid (4C) 110

6.8 Malic Acid (4C) 111

6.9 Itaconic Acid (5C) 112

6.10 Gluconic Acid (6C) 113

6.11 Citric Acid (6C) 114

6.12 Kojic Acid (6C) 114

6.13 Muconic and Adipic Acid (C6) 115

6.14 Conclusions and Perspectives 117

Acknowledgments 117

References 117

7 Production of Bioactive Compounds vs. Recombinant Proteins 125
Maria F. Salazar Affonso, Débora Bublitz Anton, Daniel Kuhn, Bruno Dahmer, Camile Wünsch, Verônica Contini, Luís F. Saraiva Macedo Timmers, Claucia F. Volken de Souza, Márcia I. Goettert, and Rodrigo G. Ducati

7.1 Introduction 125

7.2 In vitro Cell-Based Assays 126

7.3 Cell Viability Assays 127

7.4 Cell Metabolic Assays 127

7.5 Cell Survival Assays 128

7.6 Cell Transformation Assays 129

7.7 Cell Irritation Assays 129

7.8 Heterologous Expression of Recombinant Proteins of Biomedical Relevance 130

7.9 Lactic Acid Bacteria and the Production of Metabolites with Therapeutic Roles 132

7.10 Preclinical Studies 134

7.11 Computer- aided Drug Design 137

7.12 Conclusions and Perspectives 140

References 140

8 Microbial Production of Antimicrobial and Anticancerous Biomolecules 147
M. Indira, T. C. Venkateswarulu, S. Krupanidhi, and K. Abraham Peele

8.1 Introduction 147

8.2 Microbial Sources 148

8.3 Microbial Bioprospecting Methods 151

8.4 Bioactive

Compounds 153

Prospects 160

8.6 Conclusions and Perspectives 160

Acknowledgments 161

References 161

9 Microbial Fuel Cells and Plant Microbial Fuel Cells to Degradation of Polluted Contaminants in Soil and Water 170
Chung-Yu Guan and Chang-Ping Yu

9.1 Introduction 170

9.2 History 172

9.3 Electricigens 173

9.4 Electron Generation and Transfer Mechanisms of Electricigens 175

9.5 Materials 177

9.6 Design and Operation of Bioelectrochemical Systems 182

9.7 Performances of the MFCs in Actual Wastewater Treatment 187

9.8 Soil MFCs for Soil Remediation 189

9.9 PMFCs for Environmental Remediation 190

9.10 Prospectives 191

9.11 Conclusions 191

References 192

10 Microalgae-Based UV Protection Compounds 201
Jorge Alberto Vieira Costa, Juliana Botelho Moreira, Gabrielle Guimarães Izaguirres, Liliane Martins Teixeira, and Michele Greque de Morais

10.1 Introduction 201

10.2 UV Radiation 202

10.3 Protection Compounds Induced by UV Radiation 202

10.4 Microalgal Biotechnology for the Production of Photoprotective Compounds 206

10.5 Effects of UV Radiation on the Growth, Morphology, and Production of Lipids, Proteins, and Carbohydrates 209

10.6 Extraction Methods of Photoprotective Compounds 211

10.7 Prospects for Commercial Applications 213

10.8 Conclusion and Perspectives 215

References 215

11 Microorganisms as a Potential Source of Antioxidants 225
Ayerim Hernández-Almanza, Nathiely Ramírez-Guzman, Gloria A. Martínez-Medina, Araceli Loredo-Treviño, Deepak Kumar Verma, and Cristobal N. Aguilar

11.1 Introduction 225

11.2 Antioxidant- Producing Microorganisms 225

11.3 Production of Some Microbial Antioxidants and Their Action Mechanisms 226

11.4 Extraction and Purification of Microbial Antioxidants 230

11.5 Evaluation of Antioxidant Activity 231

11.6 Conclusions and Perspectives 235

References 236

12 Microbial Production of Biomethane from Digested Waste and Its Significance 242
Arun Kumar Pal, Vijay Tripathi, Prashant Kumar, and Pradeep Kumar

12.1 Introduction 242

12.2 Methane 243

12.3 Types of Waste 245

12.4 Digestion Processes of Organic Wastes 248

12.5 Conclusions and Perspectives 250

Acknowledgments 250

Conflicts of Interest 250

References 250

13 Enzymatic Biosynthesis of Carbohydrate Biopolymers and Uses Thereof 254
Manisha Sharma, Jyoti Singh Jadaun, Santosh Kumar Upadhyay, and Sudhir P. Singh

13.1 Introduction 254

13.2 Dextran 255

13.3 Chitin and Chitosan 256

13.4 Xanthan Gum 260

13.5 Bacterial Cellulose 261

13.6 Levan 263

13.7 Conclusions and Perspectives 266

Acknowledgments 266

References 266

14 Polysaccharides from Marine Microalgal Sources 278
Ratih Pangestuti, Evi Amelia Siahaan, Yanuariska Putra, and Puji Rahmadi

14.1 Introduction 278

14.2 Polysaccharides from Marine Microalgae 279

14.3 Optimization of Microalgae Culture Conditions 282

14.4 Bioactivities and Potential Health Benefits 285

14.5 Conclusions and Perspectives 288

Acknowledgment 288

References 289

15 Microbial Production of Bioplastic: Current Status and Future Prospects 295
Karishma Seem

15.1 Introduction 295

15.2 General Structure of PHA 297

15.3 Physical Properties 298

15.4 Biodegradability of PHA 298

15.5 Biosynthesis of PHA 299

15.6 Challenges of Scaling Up of PHA Production on an Industrial Scale 300

15.7 Co- Synthesis of PHA with Value-Added Products 304

15.8 Blends of PHA 305

15.9 Applications of PHA 306

15.10 Conclusions and Perspectives 309

References 309

16 Microbial Enzymes for the Mineralization of Xenobiotic Compounds 319
Ankita Chatterjee, Pritha Chakraborty, and Jayanthi Abraham

16.1 Introduction 319

16.2 Major Pollutants and Their Removal with White-Rot Fungi 320

16.3 Enzyme System of White-Rot Fungi 323

16.4 Molecular Aspect 330

16.5 Conclusions and Perspectives 331

Acknowledgement 331

Compliance with Ethical Guidelines 332

References 332

17 Functional Oligosaccharides and Microbial Sources 337
SA Belorkar

17.1 Introduction 337

17.2 Inulin and Oligofructose: The Preliminary Functional Oligosaccharides 339

17.3 GRAS and FOSHU Status 339

17.4 Conventional and Upcoming Oligosaccharides 339

17.5 Microbes and Functional Oligosaccharides 340

17.6 Arabinoxylo- Oligosaccharides 340

17.7 Sources and Properties 341

17.8 Approaches for AXOS Production 341

17.9 Isomaltooligosaccharides 342

17.10 Sources and Properties 343

17.11 Production of IMO 344

17.12 Approaches to Improve IMO Production 344

17.13 Lactosucrose 345

17.14 Novel Approaches in Lactosucrose Preparation 347

17.15 Xylooligosaccharides 347

17.16 Occurrence and Properties 348

17.17 Approaches to Improve the Efficiency of XOS 349

17.18 Conclusions and Perspectives 349

References 350

18 Algal Biomass and Biofuel Production 357
Suman Sanju, Aditi Thakur, Pragati Misra, and Pradeep Kumar Shukla

18.1 Introduction 357

18.2 Biofuels 357

18.4 Microalgae as Biofuel Biomass 360

18.5 Microalgae Culture Systems 362

18.6 MicroalgaecHarvesting 364

18.7 Processing and Extraction of Components 364

18.8 Biofuel Conversion Processes 364

18.9 Microalgal Biofuels 368

18.9.5 Biohydrogen 371

18.10 Conclusions and Perspectives 371

References 371

19 Microbial Source of Insect-Toxic Proteins 377
Tripti Yadav and Geetanjali Mishra

19.1 Introduction 377

19.2 Fungi 378

19.3 Bacteria 384

19.4 Virus 386

19.5 Conclusions and Perspectives 387

References 388

20 Recent Trends in Conventional and Nonconventional Bioprocessing 404
Saswata Goswami, Keyur Raval, Anjana, and Priyanka Bhat

20.1 Advances in Conventional Bioprocessing 404

20.2 Nonconventional Bioprocessing 409

20.3 Brief Note on the Recent Trends in Downstream Bioprocessing 413

20.4 Perfusion Culture for Bioprocess Intensification 413

20.5 Conclusions and Perspectives 416

References 416

Index 418
Sudhir P. Singh, Scientist-D, Biotechnology & Synthetic Biology, Center of Innovative and Applied Bioprocessing, Mohali, India. He has been working in the field of molecular biology and biotechnology for more than a decade. His current research is focused on gene mining and biocatalyst engineering for the development of approaches for transformation of agro-industrial residues and under- or un-utilized side-stream biomass into value-added bio-products.

Santosh Kumar Upadhyay, Assistant Professor, Department of Botany, Panjab University, Chandigarh, India. He has been working in the field of plant biotechnology for more than 14 years. His current research focuses on functional genomics.