Organic Syntheses, Volume 98
Organic Syntheses (Series Nr. 98)
1. Edition October 2022
608 Pages, Hardcover
Wiley & Sons Ltd
ISBN:
978-1-119-90394-9
John Wiley & Sons
The current volume continues the tradition of the Organic Syntheses series, providing carefully checked and edited experimental procedures that describe important synthetic methods, transformations, reagents, and synthetic building blocks or intermediates with demonstrated utility in organic synthesis. These significant and interesting procedures should prove worthwhile to many synthetic chemists working in increasingly diverse areas. A trusted guide for professionals in organic and medicinal chemistry in academia, government, and industries, including pharmaceuticals, fine chemicals, agrochemicals, and biotechnological products.
Chapter 1 Synthesis of Chiral Organoiodine Catalyst for Enantioselective Oxidative Dearomatization Reactions: N,N'-(2S,2'S)-(2-Iodo-1,3-phenylene) bis(oxy)bis(propane-2,1-diyl)bis(2,4,6-trimethylbenzamide)
Chapter 2 Chapter iral Organoiodine-catalyzed Enantioselective Oxidative Dearomatization of Phenols
Chapter 3 Reductive Deuteration of Ketones with Magnesium and D2O for the Synthesis of alpha-Deutero-o-methyl-benzhydrol
Chapter 4 Palladium-Catalyzed Acetylation of Arylbromides
Chapter 5 Cu-catalyzed Allylic Perfluoroalkylation of Alkenes Using Perfluoro Acid Anhydrides: Preparation of N-(5,5,5-Trifluoro-2-penten-1-yl)phthalimide
Chapter 6 Synthesis of a Phosphorous Sulfur Incorporating Reagent for the Enantioselective Synthesis of Thiophosphates
Chapter 7 Discussion Addendum for: Preparation of (S)-tert-ButylPyOx and Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids
Chapter 8 Palladium-Catalyzed Hydrodefluorination of Fluoroarenes
Chapter 9 Synthesis of the Isocyanide Building Block Asmic, anisylsulfanylmethylisocyanide
Chapter 10 Mild mono-Acylation of 4,5-Diiodoimidazole: Preparation of 1-(5-Iodo-1H-imidazole-4-yl)pent-4-en-1-one
Chapter 11 Enantioselective Michael-Proton Transfer-Lactamization for Pyroglutamic Acid Derivatives: Synthesis of Dimethyl-(S,E)-5-oxo-3-styryl-1-tosylpyrrolidine-2,2-dicarboxylate
Chapter 12 Preparation of 1-Hydrosilatrane, and Its Use in the Highly Practical Synthesis of Secondary and Tertiary Amines from Aldehydes and Ketones via Direct Reductive Amination
Chapter 13 Synthesis of Tetraaryl-, Pentaaryl-, and Hexaaryl-1,4-dihydropyrrolo[3,2-b]pyrroles
Chapter 14 Preparation of Hindered Aniline CyanH and Application in the Allyl-Ni-Catalyzed alpha, ß-Dehydrogenation of Carbonyls
Chapter 15 Synthesis of tert-Alkyl Phosphines: Preparation of Di-(1-adamantyl)phosphonium Trifluoromethanesulfonate and Tri-(1-adamantyl)phosphine
Chapter 16 Preparation of 1-Benzyl-7-methylene-1,5,6,7-tetrahydro-4H-benzo[d]imidazol-4-one
Chapter 17 Catalytic Diazoalkane-Carbonyl Homologation: Synthesis of 2,2-Diphenylcycloheptanone and Other Quaternary or Tertiary Arylalkanones and Spirocycles by Ring Expansion
Chapter 18 C2 Amination of Pyridine with Primary Amines Mediated by Sodium Hydride in the Presence of Lithium Iodide
Chapter 19 Synthesis and Acylation of 1,3-Thiazinane-2-thione
Chapter 20 Preparation of (Bis)Cationic Nitrogen-Ligated I(III) Reagents: Synthesis of [(pyridine)2IPh](OTf)2 and [(4-CF3-pyridine)2IPh](OTf)2
Chapter 21 Preparation of 6-(Triethylsilyl)cyclohex-1-en-1-yl Trifluoromethanesulfonate as a Precursor to 1, 2-Cyclohexadiene
Chapter 22 Discussion Addendum for: Intra- and Intermolecular Kulinkovich Cyclopropanation Reactions of Carboxylic Esters with Olefins: Bicyclo[3.1.0]hexan-1-ol and trans-2-benzyl-1-methylcyclopropan-1-ol
Chapter 23 Synthesis of Chiral Aziridine Ligands for Asymmetric Alkylation with Alkylzincs: Diphenyl((S)-1-((S)-1-phenylethyl)aziridin-2-yl)methanol
Chapter 24 Large-Scale Preparation of Oppolzer's Glycylsultam
Chapter 25 Stereoselective [2+2] Cycloadditions: Synthesis of a Tri-O-Bn-D-Glucal-derived ß-Lactam
Chapter 26 Preparation of 2-(Triethylsilyl)cyclohex-1-en-1-yl Trifluoromethanesulfonate as a Precursor to Cyclohexyne
Chapter 27 Late-stage C H Functionalization with 2,3,7,8-Tetrafluorothianthrene: Preparation of a Tetrafluorothianthrenium-salt
Index
Chapter 2 Chapter iral Organoiodine-catalyzed Enantioselective Oxidative Dearomatization of Phenols
Chapter 3 Reductive Deuteration of Ketones with Magnesium and D2O for the Synthesis of alpha-Deutero-o-methyl-benzhydrol
Chapter 4 Palladium-Catalyzed Acetylation of Arylbromides
Chapter 5 Cu-catalyzed Allylic Perfluoroalkylation of Alkenes Using Perfluoro Acid Anhydrides: Preparation of N-(5,5,5-Trifluoro-2-penten-1-yl)phthalimide
Chapter 6 Synthesis of a Phosphorous Sulfur Incorporating Reagent for the Enantioselective Synthesis of Thiophosphates
Chapter 7 Discussion Addendum for: Preparation of (S)-tert-ButylPyOx and Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids
Chapter 8 Palladium-Catalyzed Hydrodefluorination of Fluoroarenes
Chapter 9 Synthesis of the Isocyanide Building Block Asmic, anisylsulfanylmethylisocyanide
Chapter 10 Mild mono-Acylation of 4,5-Diiodoimidazole: Preparation of 1-(5-Iodo-1H-imidazole-4-yl)pent-4-en-1-one
Chapter 11 Enantioselective Michael-Proton Transfer-Lactamization for Pyroglutamic Acid Derivatives: Synthesis of Dimethyl-(S,E)-5-oxo-3-styryl-1-tosylpyrrolidine-2,2-dicarboxylate
Chapter 12 Preparation of 1-Hydrosilatrane, and Its Use in the Highly Practical Synthesis of Secondary and Tertiary Amines from Aldehydes and Ketones via Direct Reductive Amination
Chapter 13 Synthesis of Tetraaryl-, Pentaaryl-, and Hexaaryl-1,4-dihydropyrrolo[3,2-b]pyrroles
Chapter 14 Preparation of Hindered Aniline CyanH and Application in the Allyl-Ni-Catalyzed alpha, ß-Dehydrogenation of Carbonyls
Chapter 15 Synthesis of tert-Alkyl Phosphines: Preparation of Di-(1-adamantyl)phosphonium Trifluoromethanesulfonate and Tri-(1-adamantyl)phosphine
Chapter 16 Preparation of 1-Benzyl-7-methylene-1,5,6,7-tetrahydro-4H-benzo[d]imidazol-4-one
Chapter 17 Catalytic Diazoalkane-Carbonyl Homologation: Synthesis of 2,2-Diphenylcycloheptanone and Other Quaternary or Tertiary Arylalkanones and Spirocycles by Ring Expansion
Chapter 18 C2 Amination of Pyridine with Primary Amines Mediated by Sodium Hydride in the Presence of Lithium Iodide
Chapter 19 Synthesis and Acylation of 1,3-Thiazinane-2-thione
Chapter 20 Preparation of (Bis)Cationic Nitrogen-Ligated I(III) Reagents: Synthesis of [(pyridine)2IPh](OTf)2 and [(4-CF3-pyridine)2IPh](OTf)2
Chapter 21 Preparation of 6-(Triethylsilyl)cyclohex-1-en-1-yl Trifluoromethanesulfonate as a Precursor to 1, 2-Cyclohexadiene
Chapter 22 Discussion Addendum for: Intra- and Intermolecular Kulinkovich Cyclopropanation Reactions of Carboxylic Esters with Olefins: Bicyclo[3.1.0]hexan-1-ol and trans-2-benzyl-1-methylcyclopropan-1-ol
Chapter 23 Synthesis of Chiral Aziridine Ligands for Asymmetric Alkylation with Alkylzincs: Diphenyl((S)-1-((S)-1-phenylethyl)aziridin-2-yl)methanol
Chapter 24 Large-Scale Preparation of Oppolzer's Glycylsultam
Chapter 25 Stereoselective [2+2] Cycloadditions: Synthesis of a Tri-O-Bn-D-Glucal-derived ß-Lactam
Chapter 26 Preparation of 2-(Triethylsilyl)cyclohex-1-en-1-yl Trifluoromethanesulfonate as a Precursor to Cyclohexyne
Chapter 27 Late-stage C H Functionalization with 2,3,7,8-Tetrafluorothianthrene: Preparation of a Tetrafluorothianthrenium-salt
Index
