1. Edition - February 2004
155.- Euro
2004. XII, 244 Pages, Hardcover
111 Fig. (19 Colored Fig.), 20 Tab. 
- Monograph -
ISBN-10: 3-527-30633-1
ISBN-13: 978-3-527-30633-6 - Wiley-VCH, Weinheim








Short description
This is the first work devoted to the topic and draws together knowledge gained on different types of peptidomimetics and other pseudo-peptides with drug properties. As such, it includes peptoids, beta-peptides, polyamide DNA binders as well as peptide nucleic acids.
The expert authors and editor discuss chemical properties and stability, biological activity and reactivity, as well as practical aspects of synthesis, making this a prime resource for drug developers and bioorganic chemists working with these compounds.

From the contents
Versatile oligo-glycines: The many roles of peptoids in drug discovery
Beta-peptides, gamma-peptides and isosteric backbones: New scaffolds with controlled shapes
Regulation of gene expression with pyrrole-imidazole polyamides
Peptide nucleic acid: A pseudo-peptide with DNA-like properties
Alpha-helical peptide nucleic acids
DNA-cleaving pseudo-peptides