Genetic Techniques for Biological Research
A Case Study Approach
1. Edition April 2002
XII, 242 Pages, Softcover
Textbook
Short Description
This advanced textbook teaches the theory and practice of molecular genetic analysis to senior undergraduates and graduates studying genetics, molecular biology and cell biology. It uses a case study approach, with the yeast Saccharomyces as the model genetic organism, to explain the theory and practice of molecular genetic analysis. It provides information to enable readers to apply the approach to their own research project.
Further versions
Molecular Genetic Analysis is an advanced textbook to teach the theory and practice of molecular genetic analysis to senior undergraduates and graduates studying genetics, molecular biology and cell biology.
This book uses a case study approach, with the yeast Saccharomyces as the model genetic organism, to explain the theory and practice of molecular genetic analysis. It provides enough information so readers will be able to apply the approach to their own research project.
Saccharomyces cerevisiae As a Genetic Model Organism
Techniques in Cell and Molecular Biology
Saccharomyces Cell Structure
2. Techniques of Genetic Analysis
Mutant Hunts - To select or to screen (perhaps even by brute force)
Complementation analysis: How many genes are involved?
Epistasis analysis
Gene isolation and analysis of multiple mutant alleles
Suppression Analysis
Enhancement and synthetic phenotypes
Two-hybrid analysis
Advanced concepts in molecular genetic analysis
Genomic Analysis
3. Case Studies from the Saccharomyces Genetic Literature
Case Study I: Glucose Sensing and Signaling mechanisms in Saccharomyces
Case Study II: Secretion, Exocytosis and Vesicle Trafficking in Saccharomyces
Case Study III: The Cell Division Cycle of Saccharomyces
Case Study IV: Mating-type Pheromone Response Pathway of Saccharomyces
Index
