John Wiley & Sons Glycobiology of the Immune Response, Volume 1253 Cover Carbohydrates are ubiquitous, essential molecules, as important as nucleic acids and proteins yet le.. Product #: 978-1-57331-839-6 Regular price: $41.96 $41.96 In Stock

Glycobiology of the Immune Response, Volume 1253

Rabinovich, Gabriel / Cobb, Brian / van Kooyk, Yvette (Editor)

Annals of the New York Academy of Sciences

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1. Edition June 2012
252 Pages, Softcover
Wiley & Sons Ltd

ISBN: 978-1-57331-839-6
John Wiley & Sons

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Carbohydrates are ubiquitous, essential molecules, as important
as nucleic acids and proteins yet less well understood.
Mounting data demonstrate that microbial and mammalian glycans and
their protein-binding partners (lectins) play central roles in all
innate and adaptive immune responses. Indeed, programmed
remodeling of host glycans can modulate infection, autoimmunity,
and cancer, while microbial glycoconjugates can serve as canonical
innate receptor agonists that induce B cell and T cell
activation. Glycobiology of the Immune Response
explores the integration of state-of-the-art glycobiology and
immunology to raise awareness of the multifaceted roles of glycans
and lectins in the immune system

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Glycobiology of immune responses 1

Gabriel A. Rabinovich, Yvette van Kooyk and Brian A.
Cobb

Multifarious roles of sialic acids in immunity 16

Ajit Varki and Pascal Gagneux

Siglecs as sensors of self in innate and adaptive immune
responses 37

James C. Paulson, Matthew S. Macauley and Norihito
Kawasaki

Interleukin-2, Interleukin-7, T cell-mediated autoimmunity, and
N-glycosylation 49

Ari Grigorian, Haik Mkhikian and Michael Demetriou

T cells modulate glycans on CD43 and CD45 during development and
activation, signal regulation, and survival 58

Mary C. Clark and Linda G. Baum

Interplay between carbohydrate and lipid in recognition of
glycolipid antigens by natural killer T cells 68

Bo Pei, Jose Luis Vella, Dirk Zajonc and Mitchell
Kronenberg

Gelectins in acute and chronic inflammation 80

Fu-Tong Liu, Ri-Yao Yang and Daniel K. Hsu

Mechanisms underlying in vivo polysaccharide-specific
immunoglobulin responses to intact extracellular bacteria 92

Clifford M. Snapper

CD33-related siglecs as potential modulators of inflammatory
responses 102

Paul R. Crocker, Sarah J. McMillan and Hannah E.
Richards

Sulfated glycans control lymphocyte homing 112

Hiroto Kawashima and Minoru Fukuda

Acute phase glycoproteins: bystanders or participants in
carcinogenesis? 122

Eugene Dempsey and Pauline M. Rudd

Glycans, galectins, and HIV-1 infection 133

Sachiko Sato, Michel Ouellet, Christian St-Pierre and Michel J.
Tremblay

An evolutionary perspective on C-type lectins in infection and
immunity 149

Linda M. van den Berg, Sonja I. Gringhuis and Teunis B. H.
Geijtenbeck

Integrated approach toward the discovery of glycol-biomarkers of
inflammation-related diseases 159

Takashi Angata, Reiko Fuijinawa, Ayako Kurimoto, Kazuki
Nakajima, Masaki Kato, Shinji Takamatsu, Hiroaki Korekane,
Cong-Xiao Gao, Kazuaki Ohtsubo, Shinobu Kitazume and Naoyuki
Taniguchi

Novel roles for the IgG Fc Glycan 170

Robert M. Anthony, Fredrik Wermeling and Jeffrey V.
Ravetch

The effect of galectins on leukocyte trafficking in
inflammation: sweet or sour? 181

Dianne Cooper, Asif J. Iqbal, Beatrice R, Grittens, Carmela
Cervone and Mauro Perretti

Engineering cellular trafficking via
glycosyltransferase-programmed stereosubstitution 193

Robert Sackstein

The expanding role of alpha2-3 sialylation for leukocyte
trafficking in vivo 201

Markus Sperandio

Beyond glycoproteins as galectin counterreceptors: effector T
cell growth control of tumors via ganglioside GM1 206

Robert W. Ledeen, Gusheng Wu, Sabine André, David Bleich,
Guillementte Huet, Herbert Kaltner, Jürgen Kopitz and
Hans-Joachim Gabius

Online only

Polarization of host immune responses by helminth-expressed
glycans

Donald Harn Jr., Smanla Tundup and Leena Srivastava

Carbohydrate-recognition in the immune system: contributions
of NGL-based microarrays to ligand discovery

Ten Feizi

Diversity in recognition of glycans by F-type lectins and
galectins: molecular, structural, and biophysical aspects

Gerardo R. Vasta, Hafiz Ahmed, Mario A. Bianchet, José
A. Fernández-Robledo and L. Mario Amzel
"Glycobiology of the Immune Response explores the
integration of state-of-the art glycobiology and immunology to
raise awareness of the multifaceted roles of glycans and lectins in
the immune system." (European Journal of
Immunology, 1 December 2012)
Gabriel Rabinovich and Brian Cobb are the authors of Glycobiology of the Immune Response, Volume 1253, published by Wiley.