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Schleef, Martin (ed.)
DNA-Pharmaceuticals
Formulation and Delivery in Gene Therapy, DNA Vaccination and Immunotherapy

1. Edition August 2005
145.- Euro
2005. XXII, 253 Pages, Hardcover
37 Fig. (6 Colored Fig.), 11 Tab. 
- Practical Approach Book -
ISBN 978-3-527-31187-3 - Wiley-VCH, Weinheim




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Short description
Focusing on a completely new class of pharmaceuticals, this book collates the hitherto scarce literature on DNA drug formulation much desired by biotechnologists, molecular biologists and pharmacists, as well as those working in the biotechnological and pharmaceutical industries.

From the contents
Preface
DNA Vaccines: an Overview
DNA as a Pharmaceutical: Regulatory Aspects
From Bulk to Delivery: Plasmid Manufacturing and Delivery
Minimized, CpG-Depleted and Methylated DNA Vectors: Towards Perfection in Nonviral Gene Therapy
Localized Nucleic Acid Delivery: a Discussion of Selected Methods
DNA Needle Injection
Needleless Jet Injection of Naked DNA von Nonviral in vivo Gene Transfer
Plasmid Inhalation: Delivery to the Airways
Hydrodynamic Gene Delivery
DNA Pharmaceuticals for Skin Diseases
Electrotransfection: an Overview
Electrogenetransfer in Clinical Applications
Cancer Inhibition in Mice after Systematic Application of Plasmid Driven Expression of Small Interfering RNAs
Index


 





 

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