Short description The only topical book to focus on optimization, this volume addresses the needs of users wishing to improve their methods in particular in terms of throughput, accuracy and cost-effectiveness. Written by bestseller authors and scientists working for major international companies.
From the contents ESSENTIAL ASPECTS OF OPTIMIZATION Principles of HPLC Optimization Illustrated by RP-Chromatography Fast Gradient Separations pH and Selectivity in Reversed-Phase Chromatography Selecting the Correct pH-Value for HPLC Optimization of Data Evaluation in Chromatography Calibration Characteristics and Uncertainty indicating Starting-Points for Method Optimization OPTIMIZATION IN DIFFERENT LC-MODI Comparison and Choice of Columns for RP-HPLC Column Selectivity in Reversed-Phase Chromatography The Use of Principal Component Analysis for the Characterisation of Reversed-Phase Liquid Chromatographic Stationary Phases Chemometrics - A Powerful Tool for Handling a Large Number of Data Linear Free Energy Relations - Tools for Column Characterization and Method Optimization in HPLC? Column Selectivity in Reversed-Phase Liquid Chromatography Understanding Selectivity by Use of Suspended-State High Resolution Magic Angle Spinning NMR Spectroscopy Optimization in Normal-Phase HPLC Optimization of GPC/SEC Separations by Proper Selection of Stationary Phase and Detection Gel Filtration - Size Exclusion Chromatography of biopolymers Optimization in Affinity Chromatography Optimization of Chiral Separations in HPLC μLC/nano LC - Optimization and Troubleshooting Microchip-Based Liquid Chromatography - Techniques and Possibilities Ultra-Performance Liquid Chromatography HYPHENATED TECHNIQUES Immunochromatographic Techniques Enhanced Characterization and Comprehensive Analyses by 2-dimensional Chromatography LC/MS - Hints and Recommendations for Optimization and Troubleshooting LC-NMR-Coupling COMPUTER-AIDED OPTIMIZATION Computer-Facilitated HPLC Method Development Using DryLab Software ChromSword Software for Automated and Computer-Assisted Development of HPLC Methods Multifactorial Systematic Method Development and Optimization in Reversed Phase HPLC USER REPORTS NanoLC-MS/MS in Proteomics Ways for the Verification of the Robustness in RP-HPLC Separation of Complex Sample Mixtures Evaluation of an integrated procedure for the characterization of chemical libraries on the basis of HPLC-UV/MS/CLND
