1. Edition - January 2009
149.- Euro
2009. XVIII, 543 Pages, Hardcover
483 Fig., , 12 Tab. 
- Handbook/Reference Book -
ISBN-10: 3-527-31937-9
ISBN-13: 978-3-527-31937-4 - Wiley-VCH, Weinheim







Content

Sample Chapter

Index



Short description
With a list of authors reading like a "who's who" in organic chemistry, this first comprehensive book on the topic presents the necessary information in a compact manner.
Indispensable to synthetic chemists and those working in the pharmaceutical and chemical industry.

From the contents
ARYLATION REACTIONS: A HISTORICAL PERSPECTIVE
Structure and Bonding of Benzene
Syntheses of Substituted (Hetero)Arenes, and the Contents of this Book
METAL-CATALYZED COUPLING REACTIONS WITH ARYL CHLORIDES, TOSYLATES AND FLUORIDES
Introduction
Coupling Reactions of Aryl Chlorides
Coupling Reactions Aryl Fluorides
Coupling Reactions of Aryl Tosylates
PALLADIUM-CATALYZED ARYLATIONS OF AMINES AND ALPHA-C-H ACIDIC COMPOUNDS
Introduction
Palladium-Catalyzed Arylations of Amines
Palladium-Catalyzed Arylations of Alpha-C-H Acidic Compounds
COPPER-CATALYZED ARYLATIONS OF AMINES AND ALCOHOLS WITH BORON-BASED ARYLATING REAGENTS
Introduction
Discovery and Development of a New O-H Bond Arylation Reaction: From Stoichiometric to Catalytic in Copper
Mechanistic Considerations
Miscellaneous Applications
Development of a New N-H Bond Arylation Reaction
Development of a New N-H Bond Arylation Reaction: Catalytic in Copper
METAL-CATALYZED ARYLATIONS OF NONACTIVATED ALKYL (PSEUDO)HALIDES VIA CROSS-COUPLING REACTIONS
Introduction
Palladium-Catalyzed Arylations of Alkyl (Pseudo)Halides
Nickel-Catalyzed Arylations of Alkyl (Pseudo)Halides
Iron-Catalyzed Arylations of Alkyl (Pseudo)Halides
Copper- and Cobalt-Catalyzed Arylations of Alkyl (Pseudo)Halides
ARYLATION REACTIONS OF ALKYNES: THE SONOGASHIRA REACTION
Introduction
Palladium-Catalyzed Reactions: Ligands and Reaction Protocols
Alternative Metal Catalysts
Mechanism of the Sonogashira Reaction
PALLADIUM-CATALYZED ARYLATION REACTIONS OF ALKENES (MIZOROKI-HECK REACTION AND RELATED PROCESSES)
Introduction
Mizoroki-Heck Arylations
Reductive Mizoroki-Heck-Type Arylations
Oxidative Mizoroki-Heck-Type Arylations
MODERN ARYLATIONS OF CARBONYL COMPOUNDS
Introduction
Enantioselective Arylation of Aldehydes
Enantioselective Arylation of Ketones
Enantioselective Arylation of Imines
Conjugate Asymmetric Arylation
Tandem Processes
Enantioselective Friedel-Crafts Arylation
METAL-CATALYZED DIRECT ARYLATIONS (EXCLUDING PALLADIUM)
Introduction
Rhodium-Catalyzed Direct Arylations
Ruthenium-Catalyzed Direct Arylations
Iridium-, Copper- and Iron-Catalyzed Direct Arylations
PALLADIUM-CATALYZED DIRECT ARYLATION REACTIONS
Introduction
Intermolecular Arylation of Functionalized Arenes
Intramolecular Reaction of Haloaryl-Linked Arenes
Intermolecular Arylation Reactions of Heteroaromatic Compounds
MECHANISTIC ASPECTS OF TRANSITION METAL-CATALYZED DIRECT ARYLATION REACTIONS
Introduction
Palladium-Catalyzed Intramolecular Direct Arylation
Intermolecular Metal-Catalyzed Direct Arylation of Arenes
Metal-Catalyzed Heteroaryl-Aryl and Heteroaryl-Heteroaryl Bond Formation
Direct Arylation via Metallacycles
Cross-Dehydrogenative Couplings
ARYLATION REACTIONS INVOLVING THE FORMATION OF ARYNES
Introduction
Generation of Arynes
Electrophilic Coupling of Arynes
Pericyclic Reactions of Arynes
Transition Metal-Catalyzed Reactions Arynes
RADICAL-BASED ARYLATION METHODS
Introduction
SRN1-Type Radical Arylations
Homolytic Aromatic Substitutions
Arylations Using Aryl Radicals
PHOTOCHEMICAL ARYLATION REACTIONS
Introduction
Photochemical Formation of Aryl-C Bonds
Photochemical Formation of Aryl-N Bonds