|  | Gad, Shayne Cox (ed.) Preclinical Development Handbook 2-Volume Set Pharmaceutical Development
  1. Edition - April 2008 255.- Euro 2008. 2432 Pages, Hardcover - Handbook/Reference Book - ISBN-10: 0-471-21383-7 ISBN-13: 978-0-471-21383-3 - John Wiley & Sons

Short description This book brings together in one resource an overview of the preclinical process along with a compendium of methods and techniques that need to be considered when developing a new drug. The book details steps in the preclinical process including: prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, toxicity, modeling, and regulations. It includes problems that are encountered, solutions to these problems, and limitations of various methods and techniques used in determining the safety and efficacy of a drug at this stage.
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