|  | Warren, Stuart / Wyatt, Paul
Organic Synthesis
The Disconnection Approach
 2. Edition - November 2008
105.- Euro
2008. 342 Pages, Hardcover
- Textbook -
ISBN-10: 0-470-71237-6
ISBN-13: 978-0-470-71237-5 - John Wiley & Sons
Sample Chapter
Short description
In retrosynthetic analysis, a chemist will start with the structure of their target molecule and progressively cut bonds to create simpler molecules. This disconnection approach to synthesis is now a fundamental part of every organic synthesis course. Brimming with new examples, synthetic pathways, and updated material to reflect 25 years of advances in organic synthesis, this fully revised and updated second edition of the classic textbook introduces this important technique to help final year undergraduates and postgraduate organic chemistry students design their own organic syntheses.
From the contents
1. Introduction: Planning Organic Syntheses..
2. Synthons and Reagents: Aromatic Compounds.
3. Strategy I: The Order of Events.
4. One-Group C-X Disconnections.
5. Chemoselectivity.
6. Two-Group C-X Disconnections.
7. Strategy III.
8. Amine Synthesis.
9. Protecting Groups.
10. One Group C-C Disconnections I: Alcohols.
11. General Strategy A: Choosing Disconnections.
12. Stereoselectivity A.
13. One Group C-C Disconnections II: Carbonyl Compounds.
14. Regioselectivity.
15. Alkene Synthesis.
16. Strategy VII: Use of Acetylenes.
17. Diels-Alder.
18. Strategy VIII: Carbonyl Condensations.
19. 1,3-diCO Compounds.
20. Control in C=O Condensations.
21. 1,5-diCO Compounds.
22. Nitro Groups.
23. 1,2-diCO Compounds.
24. Radicals.
25. 1,4-diCO Compounds.
26. Reconnection.
27. 1,6-diCO Compounds.
28. Strategy of C=O Disconnections.
29. Saturated Heterocycles.
30. Cyclopropanes.
31. Rearrangements.
32. Four-Membered Rings.
33. Ketenes.
34. Five-Membered Rings.
35. Pericyclic Reactions.
36. Six-Membered Rings.
37. Strategy of Ring Synthesis.
38. Stereoselectivity B.
39. Aromatic Heterocycles.
40: Advanced Strategy.
|
|
|
|
