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Kukhar, Valery P. / Hudson, Harry R. (eds.)
Aminophosphonic and Aminophosphinic Acids
Chemistry and Biological Activity

1. Edition - March 2000
525.- Euro
2000. XXVI, 634 Pages, Hardcover
ISBN-10: 0-471-89149-5
ISBN-13: 978-0-471-89149-9 - John Wiley & Sons



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Short description
Aminophosphinic and aminoposphonic acids, synthetic analogs to natural amino acids, have attained a position of prominence in research--particularly in research involving the modification of physiological processes in living organisms.

From the contents
Naturally Occurring Aminophosphonic and Aminophosphinic Acids (P. Mastalerz & P. Kafarski).

Synthesis of -Aminoalkanephosphonic and -Aminoalkanephosphinic Acids (P. Kafarski & J. Zo).

Synthesis of Aminoalkanephosphonic and Aminoalkanephosphinic Acids with the Amino Substituent in Other than the -Position (V. Kukhar).

-Amino Acid Analogues Bearing Side-Chain C-P Linkages (S. Lall and R. Engel).

Asymmetric Synthesis of Aminophosphonic and Aminophosphinic Acids (V. Kukhar).

Synthesis of Phosphono- and Phosphinopeptides (P. Kafarski & B. Lejczak).

Column Chromatography of Aminophosphonic Acids and Phosphonopeptides (S. Galushko).

Physical Properties and NMR-Spectroscopic Characterization of Aminophosphonates and Aminophosphinates (G. Hägele).

Structure and Stability Constants of Metal Complexes in Solution (T. Kiss & I. Lázár).

X-Ray Crystallographic Studies (N. Choi & M. McPartlin).

Mass Spectrometry and Gas Chromatography-Mass Spectrometry of Aminoalkanephosphonic Acids (Z. Kudzin & M. Sochaki).

The Biological Activity of Phosphono- and Phosphinopeptides (P. Kafarski & B. Lejezak).

Aminophosphonic and Aminophosphinic Acids and their Derivatives as Agrochemicals (H. Hudson).

Neuroactive Aminophosphonic and Aminophosphinic Acid Derivatives (D. Jane).

Aminophosphonic and Aminophosphinic Acid Derivatives in the Design of Transition State Analogue Inhibitors: Biomedical Opportunities and Limitations (J. Oleksyszyn).

Aminophosphonic and Aminophosphinic Acids in the Design and Synthesis of HIV Protease Inhibitors (A. Peyman).

Aminophosphonic Acid Derivatives as Antithrombotic Agents (D. Green, et al.).

Aminophosphonic and Aminophosphinic Acid Derivatives as Inhibitors of Human Collagenase (R. Markwell).

Index.


 
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