Bannwarth, Willi / Hinzen, Berthold (eds.)
Combinatorial Chemistry
From Theory to Application
Methods and Principles in Medicinal Chemistry (Volume 26)
Edited by Mannhold, Raimund / Kubinyi, Hugo / Folkers, Gerd
  2., revised and expanded Edition - February 2006
212.- Euro
2006. XXII, 672 Pages, Hardcover
85 Fig., 31 Tab.
- Handbook/Reference Book -
ISBN-10: 3-527-30693-5
ISBN-13: 978-3-527-30693-0 - Wiley-VCH, Weinheim
Sample Chapter
Short description
The new edition of this practice-oriented handbook features thoroughly updated contents, including recent developments in parallel synthesis.
A new chapter on screening complements the overview of combinatorial strategy and synthetic methods.
From the contents
Purification Principles in High-Speed Solution Phase Synthesis
(S. Weinbrenner, C. Tzschucke)
Linkers for Solid-Phase Organic Synthesis (SPOS) and Combinatorial Approaches on Solid Support
(W. Bannwarth)
Cyclative Cleavage - A Versatile Concept in Solid-Phase Organic Chemistry
(J. Pernerstorfer)
C-C Bond Forming Reactions
(W. Brill, G. Papeo)
Combinatorial Synthesis of Heterocycles
(E. Felder, A. Marzinzik)
Polymer-Supported Reagents: Preparation and Use in Parallel Organic Synthesis
(B. Hinzen, M. Hahn)
Encoding Strategies for Combinatorial Libraries
(B. Hinzen)
Automation and Devices for Combinatorial Chemistry and Parallel Organic Synthesis
(C. Zechel)
Computer-Assisted Library Design
(A. Dominik)
Assays for High Throughput Screening in Drug Discovery
(C. Apfel, T. Enderle)
Appendix: Cheminformatics and Web Resources for Combinatorial Chemistry
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