1. Edition - June 2004 420.- Euro 2004. XX, 679 Pages, 2 Volumes, Hardcover 467 Fig., 94 Tab. - Handbook/Reference Book - ISBN-10: 3-527-30714-1 ISBN-13: 978-3-527-30714-2 - Wiley-VCH, Weinheim
Short description The complete spectrum of the aldol reaction is presented in this two-volume handbook. Top authors cover the fundamentals before moving on to enolates and catalytic reactions. Further sections are devoted to enzymatic as well as related reactions. A comprehensive overview of this important topic, removing the need for time-consuming research among the widely dispersed literature. With a foreword by Professor D. A. Evans.
From the contents Fundamentals and Transition State Models The Development of Titanium Enolate Based Aldol Reactions Boron and Silicon Enolates in Crossed Aldol Reaction Silver, Gold and Palladium Lewis-Acids Boron and Silicon Lewis Acids for Mukaiyama Aldol Reactions Copper Lewis Acids Tin-promoted Aldol Reactions and Their Applications to Total Syntheses of Natural Products Zirconium Alkoxides as Lewis Acids Direct Catalytic Asymmetric Aldol Reaction Using Chiral Metal Complexes Catalytic Enantioselective Aldol Additions with Chiral Lewis Bases Amine-Catalyzed Aldol Reactions Enzyme Catalyzed Aldol Additions Antibody-Catalyzed Aldol Reactions The Aldol-Tishchenko Reaction The Aldol Reaction in Natural Product Synthesis: The Epothilone Story