1. Edition - July 2008
48.90 Euro
2008. 410 Pages, Softcover
- Monograph -
ISBN-10: 0-470-02551-4
ISBN-13: 978-0-470-02551-2 - John Wiley & Sons








Short description
Incorporating the many recent developments in the field, Structure and Function in Cell Signalling is a concise and accessible introduction to the dynamic field of signal transduction. The book demystifies cell signaling through a nuts and bolts approach by illustrating the way signaling pathways are made up from common components. This active learning approach help readers understand and apply their knowledge. The book addresses the issue of variation in the numbering of key amino acids as well as featuring an accompanying website, interaction with RasMol (molecular rendering software), and exercises to aid understanding.

From the contents
Acknowledgments

Preface

1 The components and foundations of signalling

References

2 Enzymes and receptors - quantitative aspects

References

3 Modules and motifs in transduction

References

4 Protein kinase enzymes - activation and auto-inhibition

References

5 7-pass receptors and the catabolic response

References

6 Single pass growth factor receptors

References

7 G proteins (I) - monomeric G proteins

References


8 G proteins (II) - heterotrimeric G proteins

References

9 The insulin receptor and the anabolic response

References

10 Mitogens and cell cycle progression

References

Appendix 1: Worked examples

Appendix 2: RasMol: installation and use

Index