4., updated Edition - August 2009
59.90 Euro
2009. X, 114 Pages, Hardcover
84 Fig. (84 Colored Fig.), 32 Tab. 
- Practical Approach Book -
ISBN-10: 3-527-32307-4
ISBN-13: 978-3-527-32307-4 - Wiley-VCH, Weinheim






Content

Sample Chapter



Short description
This 4th, updated edition covers the latest developments in assuring the quality of diagnostic samples. An international team of respected authors summarizes the information on the variables affecting the collection, transport, storage and preparation of medical samples.

From the contents
Dream and reality - An introductory case - The importance of the preanalytical phase
BIOLOGICAL INFLUENCES
Something unavoidable - Influences of age, gender, race and pregnancy
Changing habits - Influences that can vary (diet, starvation, exercise, altitude)
May I take coffee, smoke or drink before blood sampling? - Stimulants and addictive drugs as biological influence factors
What if I take herbs? - Effects of herbs on laboratory results
COLLECTION OF SPECIMEN
When to test? - Timing of sampling
Sampling during infusion therapy? - Sequence of diagnostic and therapeutic procedures
Sampling in the supine or upright position? - Effects of posture and tourniquet
What site for sampling blood? - Phlebotomy, arterial puncture and sampling from catheters
Blood from the skin - Capillary sampling
Did the lab mix up my sample? - Techniques of sample identification
A precious sample - Cerebrospinal fluid (CSF)
A sample that is nearly always available - Urine and saliva as diagnostic probes
Plasma or serum? - Differences to be considered
Take a lavender tube! - Additives and colour codes
TRANSPORT AND STORAGE
Fax me a sample - Effects of time and temperature during transport
Samples in transit - Legal standardization for mailing samples
How to keep a sample "fresh" - Storage of samples in the laboratory
PREPARATION OF SAMPLES FOR ANALYSIS
What has to be done on specimen arrival? - Specimen processing, centrifugation, distribution
Continuous or batchwise? - Preanalytical workflow and robotics
Safety aspects during the preanalytical phase - Disposal of specimens, needles, tubes and chemicals
SPECIAL ASPECTS WITH EACH ANALYTE
What is needed before blood transfusion? - Special aspects in immuno-haematology
Why a separate tube for the coagulation test? - Special aspects in haemostaseology
Blood cells are sensitive! - Special aspects in haematological analysis
Everything from a drop of blood? - Special aspects in clinical chemistry
Special tubes for hormones and proteomics? - Preanalytical factors in immunoassays
Blood cells can provide important information - Special aspects in cellular analysis
How to handle genes - Special aspects in molecular biology
When gases evaporate - Special aspects for blood gases and ionized calcium
The right time for drugs? - Special aspects in therapeutic drug monitoring (TDM)
Bacteria, fungi, parasites and viruses - Special aspects in microbiology
ENDOGENOUS AND EXOGENOUS INTERFERENCES
Can turbid samples be used? - Effects of lipaemia
A difficult case - Pitfalls with endogenous antibodies
The serum sample looks reddish - Effects of haemolysis
Does the laboratory have to know all my drugs? - Mechanisms and treatment of drug interference
Everything under control? - Quality assurance in the preanalytical phase
References
Glossary
Index