1. Edition - February 2009
129.- Euro
2009. 608 Pages, Hardcover
- Professional Book -
ISBN-10: 0-470-03394-0
ISBN-13: 978-0-470-03394-4 - John Wiley & Sons






Sample Chapter

Short description
The Heck reaction has experienced ever-increasing importance in several areas of organometallic and organic chemistry. The first dedicated volume on this pivotal reaction, The Heck Reaction provides a comprehensive summary of Heck chemistry, including: current mechanistic understanding; catalyst development and ligand design; inter- and intramolecular Heck reactions; and regio-, diastereo-, and enantioselective variants. Readers will discover details on how to create carbon-carbon bonds and complex carbon skeletons in a highly controlled way, making this a key resource for organic chemists and advanced undergraduate and postgraduate organic chemistry students.

From the contents
Foreword by Professor Richard F. Heck


1 Mechanisms of the Mizoroki-Heck Reaction

Anny Jutand


2 Focus on Catalyst Development and Ligand Design

Irina P. Beletskaya and Andrei V. Cheprakov


3 Focus on Regioselectivity and Product Outcome in Organic Synthesis

Peter Nilsson, Kristofer Olofsson and Mats Larhed


4 Waste-Minimized Mizoroki-Heck Reactions

Lukas Gooßen and Käthe Gooßen


5 Formation of Carbocycles

Axel B. Machotta and Martin Oestreich


6 Formation of Heterocycles

Thierry Muller and Stefan Bräse


7 Chelation-Controlled Mizoroki-Heck Reactions

Kenichiro Itami and Jun-ichi Yoshida


8 The Mizoroki-Heck Reaction in Domino Processes

Lutz F. Tietze and Laura M. Levy


9 Oxidative Heck-Type Reactions (Fujiwara-Moritani Reactions)

Eric M. Ferreira, Haiming Zhang and Brian M. Stoltz


10 Mizoroki-Heck Reactions with Metals Other than Palladium

Lutz Ackermann and Robert Born


11 Ligand Design for Intermolecular Asymmetric Mizoroki-Heck Reactions

Anthony G. Coyne, Martin O. Fitzpatrick and Patrick J. Guiry


12 Intramolecular Enantioselective Mizoroki-Heck Reactions

James T. Link and Carol K. Wada


13 Desymmetrizing Heck Reactions

Masakatsu Shibasaki and Takashi Ohshima


14 Combinatorial and Solid-Phase Syntheses

Thierry Muller and Stefan Bräse


15 Mizoroki-Heck Reactions: Modern Solvent Systems and Reaction Techniques

Werner Bonrath, Ulla L´etinois, Thomas Netscher and Jan Schütz


16 The Asymmetric Intramolecular Mizoroki-Heck Reaction in Natural Product Total Synthesis

Amy B. Dounay and Larry E. Overman