1. Edition - August 2010
132.- Euro
2010. 424 Pages, Hardcover
- Practical Approach Book -
ISBN-10: 0-470-47996-5
ISBN-13: 978-0-470-47996-4 - John Wiley & Sons








Short description
Biofilm Eradication and Prevention presents the basics of biofilm formation on medical devices, diseases related to this formation, and approaches pharmaceutical researchers can take to limit this problem. The book first covers the development and characterization of biofilm on the surfaces of implanted or inserted medical devices. Then the book discusses biofilm-mediated chronic infections occurring in various organs and pharmaceutical and drug delivery knowledge gained from research in these areas. Finally, the book explores pharmaceutical approaches like lipid-and polymer-based drug delivery carriers for eradicating biofilm on device-related infections.

From the contents
PREFACE.

ACKNOWLEDGMENTS.

PART I. DEVELOPMENT AND CHARACTERIZATION OF BIOFILMS.

1. INTRODUCTION AND OVERVIEW OF BIOFILM.

2. RATIONALE FOR BIOFILM ERADICATION FROM MODERN MEDICAL DEVICES.

3. PATHOGENESIS OF DEVICE-RELATED NOSOCOMIAL INFECTIONS.

4. BIOFILM RESISTANCE-TOLERANCE TO CONVENTIONAL ANTIMICROBIAL AGENTS.

5. ANALYTICAL TECHNIQUES USEFUL TO STUDY BIOFILMS.

PART II. BIOFILM-RELATED INFECTIONS IN VARIOUS HUMAN ORGANS (NONDEVICE-RELATED CHRONIC INFECTIONS).

6. BIOFILM-RELATED INFECTIONS IN OPHTHALMOLOGY.

7. BIOFILM-RELATED INFECTIONS IN THE ORAL CAVITY.

8. IMPLICATIONS OF BIOFILM FORMATION IN CHRONIC WOUNDS AND IN CYSTIC FIBROSIS.

PART III. DRUG DELIVERY CARRIERS TO ERADICATE BIOFILM FORMATION ON MEDICAL DEVICES.

9. STRATEGIES FOR PREVENTION OF DEVICE-RELATED NOSOCOMIAL INFECTIONS.

10. LIPOSOMES AS DRUG DELIVERY CARRIERS TO BIOFILMS.

11. POLYMER-BASED ANTIMICROBIAL DELIVERY CARRIERS.

INDEX.