1. Edition - April 2010
112.- Euro
2010. 466 Pages, Hardcover
- Monograph -
ISBN-10: 0-470-19514-2
ISBN-13: 978-0-470-19514-7 - John Wiley & Sons






Sample Chapter

Short description
Evolutionary Genomics and Systems Biology focuses on the field of evolutionary genomics, an emergent area in post-genomic science. Three key aspects of evolutionary genomics are covered: the study of genomic history, the study of macromolecular complements, and the study of evolutionary aspects of systems biology. An ideal book for students and professionals in genomics, this book melds concepts in bioinformatics, evolution, genomics, structural biology, and network biology, and describes aspects of a complicated field that is attempting to understand the biocomplexity of the living world.

From the contents
Preface.

Contributors.

Part I. Evolution of Life.

1. Evolutionary Genomics Leads the Way (David Penny and Lesley J. Collins).

2. Current Approaches to Phylogenomic Reconstruction (Denis Baurain and Hervé Philippe).

3. The Universal Tree of Life and the Last Universal Cellular Ancestor: Revolution and Counterrevolutions (Patrick Forterre).

4. Eukaryote Evolutions: The Importance of the Stem Group (Anthony M. Poole).

5. The Role of Information in Evolutionary Genomics of Bacteria (Antoine Danchin and Agnieszka Sekowska).

6. Evolutionary Genomics of Yeasts (Bernard Dujon).

Part II. Evolution of Molecular Repertoires.

7. Genotypes and Phenotypes in the Evolution of Molecules (Peter Schuster).

8. Genome Evolution Studies Through Protein Structure (Philip E. Bourne, Kristine Briedis, Christopher Dupont, Ruben Valas, and Song Yang).

9. Chromosomal Rearrangements in Evolution (Hao Zhao and Guillaume Bourque).

10. Molecular Structure and Evolution of Genomes (Todd A. Castoe, A. P. Jason de Koning, and David D. Pollock).

11. The Evolution of Protein Material Costs (Jason G. Bragg and Andreas Wagner).

12. Protein Domains as Evolutionary Units (Andrew D. Moore and Erich Bornberg-Bauer).

13. Domain Family Analyses to Understand Protein Function Evolution (Adam James Reid, Sarah Addou, Robert Rentzsch, Juan Ranea, and Christine Orengo).

14. Noncoding RNA (Alexander Donath, Sven Findei², Jana Hertle, Manja Marz, Wolfgang Otto, Christine Schulz, Peter F. Stadler, and Stefan Wirth).

15. Evolutionary Genomics of microRNAs and Their Relatives (Andrea Tanzer, Markus Reister, Jana Hertel, Clara Isabel Bermudez-Santana, Jan Gorodkin, Ivo L. Hofacker, and Peter F. Stadler).

16. Phylogenetic Utility of RNA Structure: Evolution's Arrow and Emergence of Early Biochemistry and Diversified Life (Feng-Jie Sun, Ajith Harish, and Gustavo Caetano-Anollés).

Part III. Evolution of Biological Networks.

17. A Hitchhiker's Guide to Evolving Networks (Charles G. Kurland and Otto G. Berg).

18. Evolution of Metabolic Networks (Eivind Almaas).

19. Single-Gene and Whole-Genome Duplications and the Evolution of Protein-Protein Interaction Networks (Grigoris Amoutzias and Yves Van de Peer).

20. Modularity and Dissipation in Evolution of Macromolecular Structures, Functions, and Networks (Gustavo Caetano-Anollés, Liudmila Yafremava, and Jay E. Mittenthal).

Index.