Kurzbeschreibung The only topical book to focus on optimization, this volume addresses the needs of users wishing to improve their methods in particular in terms of throughput, accuracy and cost-effectiveness. Written by bestseller authors and scientists working for major international companies.
Aus dem Inhalt ESSENTIAL ASPECTS OF OPTIMIZATION Principles of HPLC Optimization Illustrated by RP-Chromatography Fast Gradient Separations pH and Selectivity in Reversed-Phase Chromatography Selecting the Correct pH-Value for HPLC Optimization of Data Evaluation in Chromatography Calibration Characteristics and Uncertainty indicating Starting-Points for Method Optimization OPTIMIZATION IN DIFFERENT LC-MODI Comparison and Choice of Columns for RP-HPLC Column Selectivity in Reversed-Phase Chromatography The Use of Principal Component Analysis for the Characterisation of Reversed-Phase Liquid Chromatographic Stationary Phases Chemometrics - A Powerful Tool for Handling a Large Number of Data Linear Free Energy Relations - Tools for Column Characterization and Method Optimization in HPLC? Column Selectivity in Reversed-Phase Liquid Chromatography Understanding Selectivity by Use of Suspended-State High Resolution Magic Angle Spinning NMR Spectroscopy Optimization in Normal-Phase HPLC Optimization of GPC/SEC Separations by Proper Selection of Stationary Phase and Detection Gel Filtration - Size Exclusion Chromatography of biopolymers Optimization in Affinity Chromatography Optimization of Chiral Separations in HPLC μLC/nano LC - Optimization and Troubleshooting Microchip-Based Liquid Chromatography - Techniques and Possibilities Ultra-Performance Liquid Chromatography HYPHENATED TECHNIQUES Immunochromatographic Techniques Enhanced Characterization and Comprehensive Analyses by 2-dimensional Chromatography LC/MS - Hints and Recommendations for Optimization and Troubleshooting LC-NMR-Coupling COMPUTER-AIDED OPTIMIZATION Computer-Facilitated HPLC Method Development Using DryLab Software ChromSword Software for Automated and Computer-Assisted Development of HPLC Methods Multifactorial Systematic Method Development and Optimization in Reversed Phase HPLC USER REPORTS NanoLC-MS/MS in Proteomics Ways for the Verification of the Robustness in RP-HPLC Separation of Complex Sample Mixtures Evaluation of an integrated procedure for the characterization of chemical libraries on the basis of HPLC-UV/MS/CLND
