|  | Francotte, Eric / Lindner, Wolfgang (Hrsg.)
Chirality in Drug Research
Methods and Principles in Medicinal Chemistry (Band 33)
Herausgegeben von Mannhold, Raimund / Kubinyi, Hugo / Folkers, Gerd
 1. Auflage September 2006
182,- Euro
2006. XIX, 351 Seiten, Hardcover
146 Abb. (6 Farbabb.), 22 Tab.
- Monographie -
ISBN 978-3-527-31076-0 - Wiley-VCH, Weinheim
Preis inkl. Mehrwertsteuer zzgl. Versandkosten.
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| Kurzbeschreibung
Synthesis, purification, analysis and pharmacology of chiral drugs: Current strategies for mastering the challenge of chirality in drug development. Required reading for medicinal and pharmaceutical chemists.
Aus dem Inhalt
INTRODUCTION
Chiral drugs from a historical point of view (J. Gal)
SYNTHESIS
Stereoselective synthesis of chiral drugs (H. Federsel)
Chiral drugs from natural source (F. Petersen)
Biotransformation methods for preparing chiral drugs and drug intermediates (M. Müller, M. Wubbolts)
SEPARATIONS
Resolution of chiral drugs and drug intermediates by crystallisation (K. Saigo)
Resolution of chiral drugs by preparative chromatography (E. Francotte)
ANALYSIS
Stereoselective chromatographic methods for drug analysis (W. Lindner)
CE-MS for the quantitative analysis of chiral drugs (J. Veuthey)
Spectrosopic methods for chiral drug analysis (N. Harada)
Modeling of chiral drug-receptor interactions (G. Folkers)
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