|  | Ottow, Eckhard / Weinmann, Hilmar (Hrsg.)
Nuclear Receptors as Drug Targets
Methods and Principles in Medicinal Chemistry (Band 39)
Herausgegeben von Mannhold, Raimund / Kubinyi, Hugo / Folkers, Gerd
 1. Auflage August 2008
189,- Euro
2008. XXIV, 498 Seiten, Hardcover
90 Abb. (12 Farbabb.), 32 Tab.
- Handbuch/Nachschlagewerk -
ISBN 978-3-527-31872-8 - Wiley-VCH, Weinheim
Preis inkl. Mehrwertsteuer zzgl. Versandkosten.
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| Kurzbeschreibung
Drug development aspects of all human nuclear receptors are systematically treated here, including recently characterized receptors such as PPAR, FXR and LXR. Authors from leading pharma companies present examples and real-life data from their work.
Aus dem Inhalt
Nuclear Receptors as Modern Drug Targets - a Historic Perspective
Targeting the Nuclear Receptor - Cofactor Interaction
Untangling the Estrogen Receptor Web
Subtype Selective Estrogens
Estrogen Receptors as Therapeutic Targets in Breast Cancer
Progesterone Receptor and Progestines
Progesterone Receptor Antagonists
Nonsteroidal Tissue Selective Androgen Receptor Modulators
The Glucocorticoid Receptor as Target for Classic and Novel Anti-inflammatory Therapy and Novel Glucocorticoid Receptor Ligands
Vitamin D Analogs as Modulators of Vitamin D Receptor Action
PPARs: Therapeutic Targets for Metabolic Disease and Type 2 Diabetes
Retinoids in Clinical Use
Nuclear Receptors as Targets in Cardiovascular Diseases
NURR77 Family of Nuclear Receptors and its Modulators
Induction of Drug Metabolism: The Role of Nuclear Receptors
Nuclear Receptor Targeted Screening Libraries and Chemogenomics Approaches
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