1. Auflage - April 2009
99,90 Euro
2009. XXXIII, 481 Seiten, Hardcover
67 Abb. (7 Farbabb.), 11 Tab. 
- Lehrbuch -
ISBN-10: 3-527-31925-5
ISBN-13: 978-3-527-31925-1 - Wiley-VCH, Weinheim

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Inhalt

Probekapitel

Index



Langtext
Einen Schritt weiter als herkömmliche Lehrbücher geht diese Einführung in die Biochemie und Zellbiologie intrazellulärer Redoxprozesse. Die Autoren erklären komplizierte wissenschaftliche Zusammenhänge gut verständlich, sogar unterhaltsam, und lassen den Stoff in vielen Anwendungsbeispielen lebendig werden.

Aus dem Inhalt
Introduction
Biological Systems Relevant for Redox Signaling and Control
Cellular Generation of Oxidants: Relation to Oxidative Stress
The Chemical Basis of Biological Redox Control
Protein Glutathiolation
Structure and Function of the Human Peroxiredoxin-Based Antioxidant System: the Interplay between Peroxiredoxins, Thioredoxins, Thioredoxin Reductases, Sulfiredoxins and Sestrins
Hydrogen Peroxide and Cysteine Protein Signaling Pathways
Protein Tyrosine Phosphatases as Mediators of Redox Signaling
Hypoxia-Induced Gene Regulation through Hypoxia Inducible Factor-1a
Eicosanoid-Based Signaling
Redox-Controlled Transcription Factors and Gene Expression
Nitric Oxide Regulation in Redox Signaling
Is Hydrogen Sulfide a Regulator of Nitric Oxide Bioavailability in the Vasculature?
Aspects of Nox/Duox Signaling
Photodynamic Therapy with Aminolevulinic Acid and Iron Chelators: A Clinical Example of Redox Signaling
Oxidative Stress and Apoptosis
Redox Regulation of Apoptosis in Immune Cells
Redox Control in Human Disease with a Special Emphasis on the Peroxiredoxin-Based Antioxidant System
Free Radicals and Mammalian Aging