Autoimmune Diseases and Treatment

Only in very recent times have therapies been developed that are
specific to a particular manifestation of autoimmune disease, and
these have begun to replace the all-purpose remedies of the past 30
years. This volume, which draws on the principles of immunology
presented in Volume 1050 (Autoimmunity: Concepts and Diagnosis
at the Cutting Edge), extends these concepts to the realm of
clinical findings and current therapy for many autoimmune and
connective tissue disorders.



Both organ-specific and organ-nonspecific diseases are covered,
and one section is entirely focused on treatment. Treatments using
cytokines, chemokines, cognate receptors, and genetic interactions
are particularly prominent in these reports, and attention is also
paid to the increasing use of intravenous imunoglobulins and both
monoclonal and imunosuppressive agents. A therapeutic void remains,
but the work reported on here contributes considerably to the
effort to fill that void.

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