The Art of Process Chemistry
1. Auflage Oktober 2010
XVI, 282 Seiten, Hardcover
296 Abbildungen (31 Farbabbildungen)
38 Tabellen
Handbuch/Nachschlagewerk
Kurzbeschreibung
Providing vital knowledge for the pharmaceutical industry and process chemists, this ready reference presents successful strategies for the hottest drug candidates, showing how to manufacture valuable products in an economical, sustainable and robust way.
ISBN:
978-3-527-32470-5
Wiley-VCH, Weinheim
Aus diesem Band bezieht der Verfahrenschemiker in der pharmazeutischen Industrie unentbehrliche Informationen zur Weiterentwicklung viel versprechender Leitstrukturen. Demonstriert wird Planung und Umsetzung ökonomisch sinnvoller, nachhaltiger und belastbarer Herstellungsverfahren.
Preface
Efavirenz®, a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI), and a Previous Structurally Related Development Candidate
CCR5 Receptor Antagonist
5a-Reductase Inhibitors - The Finasteride Story
Rizatriptan (Maxalt®): A 5-HT1D Receptor Agonist
SERM: Selective Estrogen Receptor Modulator
HIV Integrase Inhibitor: Raltegravir
Cyclopentane-Based NK1 Receptor Antagonist
Glucokinase Activator
CB1R Inverse Agonist - Taranabant
Efavirenz®, a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI), and a Previous Structurally Related Development Candidate
CCR5 Receptor Antagonist
5a-Reductase Inhibitors - The Finasteride Story
Rizatriptan (Maxalt®): A 5-HT1D Receptor Agonist
SERM: Selective Estrogen Receptor Modulator
HIV Integrase Inhibitor: Raltegravir
Cyclopentane-Based NK1 Receptor Antagonist
Glucokinase Activator
CB1R Inverse Agonist - Taranabant
Nobuyoshi Yasuda received his bachelor from Tokyo Institute of Technology under the direction of Professor Teruaki Mukaiyama and Professor Hisashi Takei and his mater degree from the same university under the direction of Professor Hisashi Takei. After working at Fujisawa Pharmaceutical Company, Japan as a Medicinal Chemist, he received Ph. D. from Tokyo Institute of Technology in 1987. After spend one year as a postdoctoral fellow under Professor Robert M. Williams at Colorado State University from 1988 to 1989, he joined in Process Chemistry, Merck Research Laboratories in 1990. He has over 60 publications and over 50 patents.