Neuroendocrine and Immune Crosstalk, Volume 1088
Annals of the New York Academy of Sciences
1. Auflage Februar 2007
436 Seiten, Softcover
Wiley & Sons Ltd
Crosstalk between the neuroendocrine and immune systems plays an
essential role in inflammatory, autoimmune, and allergic diseases.
An international group of scientists from the fields of
neurobiology, neuroendocrinology, immunology, and behavioral
sciences reports here on recent advances in our understanding of
the communication and modulation taking place between the
neuroendocrine and immunological systems.
In an effort to incorporate all recent knowledge in this field,
broad aspects of endocrinology and neuropsychiatric and autoimmune
disorders is included, with special attention given to recent
progress in molecular biology and genetics.
In particular, the volume focuses on diseases of the nervous
system and their modulation by the immune and endocrine systems, as
well as on the neuroimmunomodulation of inflammatory, autoimmune,
and allergic diseases with an emphasis on the female gender.
Special care has been taken by the editors to balance basic and
clinical information. The volume is divided into sections: the
cytokine and neuropeptide signal transduction systems and their
immunomodulatory properties, the neuroendocrine immune basis of
rheumatic disease, models of inflammation, the immunology of
neuropsychiatric and allergic disorders, neuroendocrine and
autoimmune adaptations in aging, neuroimmune interactions in
chronic pain disorders and infectious diseases, and finally a
structural and functional overview of the stress system.
Clinical applications have been extrapolated from the basic
knowledge and physiology of neuroimmune interactions, so this
volume will provide a useful update for both researchers and
clinicians.
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An Overview of the Volume: Chrousos.
1. Molecular Understanding of Cytokine-Steroid Hormones
Dialogue: Implications for Human Diseases: Artz.
2. Chronology of Advances in Neuroendocrine Immunomodulation:
McCann.
3. Regulation of Dendritic Cell Differentiation by Vasoactive
Intestinal Peptide: Therapeutic Applications on Autoimmunity and
Transplantation: Delgado.
4. alpha2-Adrenergic Receptors Decrease DNA Replication and
Cell Proliferation and Induce Neurite Outgrowth in Transfected Rat
Pheochromocytoma Cells: Flordelis.
5. Thymus-Dependent T Cell Tolerance of Neuroendocrine
Functions: Principles, Reflections and Implications for
Tolerogenic/Negative Self-Vaccination: Geenen.
6. Neuroendocrine Regulation of Skin Dendritic Cells:
Granstein.
7. The Mitochondrion as a Primary Site of Action of Regulatory
Agents Involved in Neuroimmunomodulation: Sekeris.
8. The Role of Stress in the Clinical Expression of Thyroid
Autoimmunity: Tsatsoulis.
9. Neural correlates of IgE-mediated allergy: Neto.
10. Pheochromocytoma: Physiopathologic Implications and
Diagnostic Evaluation: Zapanti.
11. Adrenocortical Tumorigenesis: Reinke.
12. Participation of the EndoCannabinoid System in the Effect of
TNF-a on Hypothalamic Release of Gonadotropin-Releasing Hormone
(LHRH): Rettori.
13. Role of Thymulin or its Analogue as a New Analgesic
Molecule: Dardenne.
14. Immunoneuroendocrine Interactions in Chagas Disease:
Savino.
15. Roles of Glia-Derived Cytokines on Neuronal Degeneration and
Regeneration: Suzumura.
16. PPARg, a Lipid Activated Transcription Factor as a Regulator
of Dendritic Cell Function: Nagy.
17. Brain Cytokines and the 5-HT System During Poly I:C-Induced
Fatigue: Katafuchi.
18. Hypothalamic-Pituitary-Adrenal Axis Function in
Sjogren's Syndrome: Mechanisms of Neuroendocrine and Immune
System Homeostasis: Johnston.
19. Immunomodulation: The Future Cure for Allergic Diseases:
Tsitoura.
20. The Role of Chaperone Proteins in Autoimmunity:
Tzioufas.
21. Therapeutic Management of Chronic Neuropathic Pain Under the
Magnifying Glass: Vadaluka.
22. The Role of Stress in Asthma: Insight from Studies on the
Effect of Acute and Chronic Stressors in Models of Airway
Inflammation: Vlagoftis.
23. Interleukin-6: A Cytokine and/or a Major Modulator of the
Response to Somatic Stress: Mastorakos.
24. Annexin 1, Glucocorticoids and the Neuroendocrine-Immune
Interface: Buckingham.
25. The Role of Toll-like Receptors in the Immune-Adrenal
Crosstalk: Bornstein.
26. Title TBA: Chrousos.
27. Neurosteroids as Endogenous Inhibitors of Neuronal Cell
Apoptosis in Aging: Gravanis.
28. Local Amplification of Glucocorticoids: Seckl.
29. Beyond Heart Rate Variability: Vagal Regulation of
Allostatic Systems: Thayer.
30. Title TBA: Madianos.
31. Immunomodulatory Properties of Substance P: Gastrointestinal
System as a Model: Pothoulakis.
32. Critical Role of Mast Cells in Allergy and Inflammation.
33. Dialogue between the Brain and the Immune System in
Inflammatory Arthritis: Vassilopoulos.
Index of Contributors
Gregory A. Kaltsas, MD, FRCP, teaches at the Division of Endocrinology, Department of Pathophysiology, Medical School, National and Kapodistrian University of Athens, Greece.
