The Handbook of Homogeneous Hydrogenation

Historic introduction and mechanism of homogeneous hydrogenation
Hydrogenation kinetics
Spectroscopic techniques in homogeneous hydrogenation
Homogeneous hydrogenation of alkenes, alkynes and dienes
Homogeneous hydrogenation of aldehydes, ketones, esters and anhydrides
Aromatic and heteroaromatic hydrogenation
Homogeneous hydrogenation of CO2
(Aromatic) Dehalogenation reactions
Homogeneous polymer hydrogenation
Transfer hydrogenation
Diastereoselective hydrogenations
Dehydrogenations of alkanes and alcohols
Asymmetric olefin hydrogenation
Asymmetric ketone and beta-ketoester hydrogenations (including mechanism)
Asymmetric hydrogenation of alpha-ketoesters
Asymmetric C=N hydrogenation
Asymmetric transfer hydrogenation
High throughput experimentation and ligand libraries
Industrial applications
Two-phase aqueous hydrogenations
Homogeneous hydrogenations in neoteric solvents
Immobilisation techniques
Hydrogen activation in biological systems and model systems
Transition metal catalysed regeneration of hydrogenase cofactors
Catalyst deactivation
Chemical engineering aspects

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Kees Elsevier was born in 1957 in Den Haag, The Netherlands. He obtained his masters and PhD in chemistry at Utrecht University (1984) with Dr P. Vermeer and Professor H.J.T. Bos, on the topic of "transition-metal mediated synthesis of chiral allenes". Subsequently he moved to the University of Amsterdam, where he has developed his interests in organometallic chemistry and catalysis employing late-transition-metal compounds. He became associate professor in 1991, and then occupied the John van Geuns chair for developing transition-metal-NMR spectroscopy from 1995 till 1999. Since 1999 he holds the chair of Molecular Inorganic Chemistry at the University of Amsterdam. He has been visiting professor twice at the Weizmann Institute of Science, Israel, and at the Universities of Strasbourg and Toulouse (France). He is co-author of about 180 scientific papers on various topics in organometallic chemistry, homogeneous catalysis, and (transition metal) NMR spectroscopy, including contributions to several books. He has lately focused on Pd-catalyzed hydrogenations, involving N-ligands and N-heterocyclic carbenes, as well as catalysis involving aggregates (micelles and vesicles) of metallo-amphiphiles. He has supervised 20 PhD graduations. Kees serves on the advisory board of several scientific journals and he is scientific director of the Holland Research School of Molecular Chemistry.

Hans de Vries was born in Amsterdam, the Netherlands (1951). In 1979 he received his Ph.D from the University of Groningen, were he worked under the guidance of Richard M. Kellogg on chiral, bridged dihydropyridines as NADH-mimetics. After a postdoctoral stint at Brandeis University, Waltham, USA with Jim Hendrickson (total synthesis of Methoxatin or PQQ) from 79-81 he moved back to Europe. From 1982-1988 he worked as medicinal chemist for Sandoz, first in Vienna, afterwards in London. Being more interested in chemistry than drugs he moved back to the Netherlands, were he took up employment with DSM, a multinational specialty chemicals company. His current job is Principal Scientist Homogeneous Catalysis for Fine Chemicals. Since 1998 he has been appointed as part-time professor at the University of Groningen. In 2000 he was appointed visiting industrial professor at the Univeristy of Bristol. During 2005 he was a visiting professor at the Université Louis Pasteur, Strasbourg. His research interests are in the area of asymmetric hydrogenation (MonoPhos), aromatic substitution ("homeopathic" palladium), hydroformylation, metathesis, combinations of enzymes with transition metal catalysis, HTS, combinatorial catalysis and process intensification. He is (co-)author of 20 patents and over 100 publications. He is married and has three children.

J. G. de Vries, DSM Research, Department of Fine Chemicals, The Netherlands; C. J. Elsevier, University of Amsterdam, The Netherlands