The genetic dissection of human primary immunodeficiency is
expanding at full speed, in at least two directions. Some
investigators pursue the dissection of well-known clinical
phenotypes, for which the count of genetic etiologies seems to be
endless, whereas others begin the search for inborn errors
underlying new phenotypes, infectious and otherwise. The field of
primary immunodeficiency is also expanding in other ways, with new
therapeutic approaches, and with the care of patients in regions of
the world where these diseases were unheard of less than a decade
ago. The volume provides an overview of the field of medical
genetics and its progress in 2011.



Volume I opens with a dialog between the volume editors on the
definition of "primary immunodeficiencies (PIDs);"
additional papers in this volume focus on PIDs in Latin America,
Eastern and Central Europe, North Africa, Turkey, Asia, Iran, and
the South Pacific. Volume II focuses on new developments in
PIDs, insights into PID pathophysiology, and PIDs in India and the
Middle East.

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