Working in Biosafety Level 3 and 4 Laboratories
A Practical Introduction
1. Auflage Oktober 2013
152 Seiten, Softcover
46 Abbildungen (21 Farbabbildungen)
The first training manual for new staff working in BSL3/4 labs, this book is based on a course which has been adopted as a standard throughout the EU. This book will be a much welcomed tool worldwide to train staff and prevent accidents in BSL3/4 settings.
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The first training manual for staff working in BSL3/4 labs, this book is based on a course that has been approved as a standard throughout the EU.
It covers bio-containment, hazard criteria, the categorization of microbes, technical specifications for BSL-3 and ABSL-3 laboratories, personal protective gear, and shipping BSL-3 and BSL-4 organisms according to UN and IATA regulations. It also examines the efficacy of inactivation procedures, fumigation, learning from a history of lab accidents, handling samples submitted for diagnostic testing, and bridging the gap between the requirements of bio-containment and diagnostics.
The result is a welcome tool for training new personnel, as well as a useful reference for all permanent staff working in BSL3/4 labs.
Introduction (Manfred Weidmann)
Laboratory Biosafety in Containment Laboratories (Annette A Kraus and Ali Mirazimi)
Hazard criteria and categegoisation of microbes: Classification systems (Nigel J. Silman)
Technical and practical aspects of BSL-3 laboratories (Frank T. Hufert and Manfred Weidmann)
Animal biosafety level 3 facility - enhancements when dealing with large animals (Abad F.X., Solanes D., Domingo M.)
Personal Protective Equipment (Nigel J Silman)
Shipping of infectious substances according IATA DGR regulations (Mandy Elschner and Martin Heller)
Disinfection and decontamination (Patrick Butaye)
Fumigation of Spaces (Nigel J. Silman)
Learning from a history of laboratory accidents (Manfred Weidmann)
Bridging the gap between requirements of bio-containment and diagnostics (Manfred Weidmann, Frank T.Hufert, Nigel Silman)
Risk Assessment Procedures (Asa Szekely Björndal)
Biosecurity (Juergen Mertsching)
Patrick Butaye is a senior researcher active at the Veterinary and Agrochemical Research center and a professor at the University of Ghent, Faculty of Veterinary medicine. He obtained his academic degrees at the University of Ghent. He authored and co-authored in more than 70 international scientific publications.
Manfred Weidmann is a senior scientist at the Department of Virology of the University Medical Center Göttingen Germany. He obtained his degree from the Johannes-Gutenberg University of Mainz working on the pathogenesis of Clostridium difficille. Ever since he has worked on developing rapid diagnostic tools for the detection of arboviruses and haemorrhagic fever viruses in cooperation with partners from third world countries. He obtained the 2003 Abbot Diagnostic Award. He authored and co-authored 28 international scientific publications.
Nigel Silman is the Strategic Coordinator for Research & Development at the Health Protection Agencys' Centre for Emergency Preparedness & Response at Porton Down in the UK. He is the HPA research lead for Diagnostics and Detection and also responsible for the scientific overview of specialist reference and contract microbiology services for a range of exotic & emerging infectious diseases. He has authored and co-authored 26 international scientific publications.