The Design of Studies for Medical Research
1. Auflage Februar 2005
286 Seiten, Softcover
Wiley & Sons Ltd
Kurzbeschreibung
Properly conducted medical studies, following the principles of scientific experimentation, provide the only reliable basis for evaluating the efficacy and safety of new treatments. It is vital that these be based on carefully formulated research protocols. The Design of Studies for Medical Research describes what principles can be used to structure research effectively and to allow for the necessary degree of accuracy. With the increased emphasis on evidence-based medicine, this book will be an essential resource for any group conducting studies at the interface of clinical and laboratory research.
Essential Reading for Medical Research
Good design is a pre-requisite for successful medical research and The Design of Studies for Medical Research shows just how this can be achieved. The book focuses on how to effectively design studies and covers all key aspects of the process:
* How to take samples
* How to randomise
* Questionnaire and form design
* Sample size determination
* Design of laboratory experiments
* Design of clinical trials
* Design of epidemiological studies
This book is for anyone working in medical research, from the laboratory through to general practice and public health. It will be ideal for anyone embarking upon research for the first time or submitting a research proposal for funding, but is of relevance to all health and allied health professionals
* Includes examples from the medical literature
* Highlights and summarises key concepts
Chapter 1. What is Evidence.
Chapter 2. Measurement, Forms and Questionnaires.
Chapter 3. Principles of Study Size Calculation.
Chapter 4. Randomisation.
Chapter 5. Cross-sectional Longitudinal Studies.
Chapter 6. Surveys, Cohort and Case-Control Studies.
Chapter 7. Clinical Trails - General Issues.
Chapter 8. Early Clinical Trials.
Chapter 9. Phase III Trials.
Chapter 10. Diagnosis.
Chapter 11. Prognostic Factor Studies.
References.
Tables.
Index.
"...a very good attempt to discuss various aspects of clinical research..." (Journal of Biopharmaceutical Statistics, July/August 2006)
"This is a well researched, well written, thoughtful, and...easy to read primer...a valuable addition to books for research physicians, medical students, and others..." (Doody's Health Services)
"...this book is surprisingly refreshing...could be used in any number of situations with equality utility..." (Canadian Journal of Medical Laboratory Science, 2005)
Michael J. Campbell, Medical Statistics Group, Institute of General Practice and Primary Care, School of Health and Related Sciences, University of Sheffield, UK